Crystal structure of the DNA modifying enzyme β-glucosyltransferase in the presence and absence of the substrate uridine diphosphoglucose

EMBO Journal

Volumn 13, Issue 15, 1994, Pages 3413-3422

  Vrielink, Alice ^a,d   Rüger, Wolfgang ^b   Driessen, Huub P C ^c   Freemont, Paul S ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b RUHR UNIVERSITY BOCHUM   (Germany)

^c UNIVERSITY OF LONDON   (United Kingdom)

^d MCGILL UNIVERSITY   (Canada)

Author keywords

DNA modification; Enzyme; Glucosylation; T phage; X ray crystal structure

Indexed keywords

GLUCOSYLTRANSFERASE; RECOMBINANT PROTEIN; URIDINE DIPHOSPHATE; URIDINE DIPHOSPHATE GLUCOSE;

ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DNA MODIFICATION; ELECTRIC POTENTIAL; ENZYME BINDING; ENZYME CONFORMATION; ENZYME STRUCTURE; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; PRIORITY JOURNAL; PROTEIN DOMAIN;

T PHAGE;

EID: 0027965664     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1994.tb06646.x     Document Type: Article

References (55)

1. Adzhubei,A.A. and Sternberg,M.J.E. (1993) J. Mol. Biol., 229, 472-493.
2. Anderson,C.M., Stenkamp,R.E. and Steitz,T.A. (1978) J. Mol. Biol., 123, 15-33.
3. Bennett,W.S. and Steitz,T.A. (1978) Proc. Natl Acad. Sci. USA, 75, 4848-4852.
4. Bennett,W.S. and Steitz,T.A. (1980) J. Mol. Biol., 140, 211-230.
5. Bernards,A., VanHarten-Loosbroek,N. and Borst,P. (1984) Nucleic Acids Res., 12, 4153-4170.
6. Brünger,A.T., Kuriyan,J. and Karplus,M. (1987) Science, 235, 458-460.
7. Cheng,X., Kumar,S., Posfai,J., Pflugrath,J.W. and Roberts,R.J. (1993a) Cell, 74, 299-307.
8. Cheng,X., Kumar,S., Sha,M. and Roberts,R.J. (1993b) Acta Crystallogr., A49 (Suppl.), 61.
9. Cox,G.S. and Conway,T.W. (1973) J. Virol., 12, 1279-1287.
10. Dharmalingam,K. and Goldberg,H.B. (1979) Virology, 96, 393-403.
11. Eklund,H., Samama,J.P. and Jones,T.A. (1984) Biochemistry, 23, 5982-5996.
12. Freemont,P.S. and Rüger,W. (1988) J. Mol. Biol., 203, 525-526.
13. Freemont,P.S., Friedman,J.M., Beese,L.S., Sanderson,M.R. and Steitz,T.A. (1988) Proc. Natl Acad. Sci. USA, 85, 8924-8928.
14. Gommers-Ampt,J.H., VanLeeuwen,K. DeBeer,A.L.J., Vliegenthart, J.F.G., Dizdaroglu,M., Kowalak,J.A., Crain,P.F. and Borst,P. (1993) Cell, 75, 1129-1136.
15. Gram,H. and Rüger,W. (1985) EMBO J., 4, 257-264.
16. Jones,T.A., Zou,J.-Y., Cowan,S. and Kjeldgaard,M. (1991) Acta Crystallogr., A47, 110-119.
17. Josse,J. and Kornberg,A (1962) J. Biol. Chem., 237, 1968-1976.
18. Kabsch,W. and Sander,S. (1983) Biopolymers, 22, 2577-2637
19. Kang,C.H., Shin,W.-C., Yamagata,Y., Gokcen,S., Ames,G.F.-L. and Kim,S.-H. (1992) J. Biol. Chem., 266, 23893-23899.
20. Kornberg,S.R., Zimmerman,S.B. and Kornberg,A. (1961) J. Biol. Chem., 236, 1487-1493.
21. Kraulis,P.J. (1991) J. Appl. Crystallogr., 24, 946-950.
22. Labahn,J., Granzin,J., Schluckebier,G., Robinson,D.P., Jack,W.H., Schildkraut,I. and Saenger,W. (1994) Proc. Natl Acad. Sci. USA, in press.
23. Lamm,N., Wang,Y., Mathews,C.K. and Rüger,W. (1988) Eur. J. Biochem., 172, 553-563.
24. Lehman,I.R. and Pratt,E.A. (1960) J. Biol. Chem., 235, 3254-3259
25. Mathews,C.K., Kutter,E.M., Mosig,G. and Berget,P.B. (eds) (1983) Bacteriophage T4. American Society for Microbiology, Washington.
26. Messerschmidt,A. and Pflugrath,J.W. (1987) J. Appl. Crystallogr., 20, 306-315.
27. Mokulskaya,T.D., Gorlenko,A.M., Zumchuk,L.A., Bogdanova,E.S., Mokulskii,M.A., Goldfarb,D.M. and Khesin,R.B. (1966) Biokhimiya, 31, 749-759.
28. Moore,M.H., Gulbis,J.M., Dodson,E.J., Demple,B. and Moody,P.C.E. (1994) EMBO J., 13, 1495-1501.
29. Mosig,G. and Eiserling,F. (1988) In Calendar,R. (ed.), The Bacteriophages. Plenum Publishing Corp., New York, pp. 521-606.
30. Oh,B.-H., Pandit,J., Kang,C.-H., Nikaido,K., Goken,S., Ames,G.F.-L. and Kim,S.-H. (1993) J. Biol. Chem., 268, 11348-11355.
31. Rabussay,D. (1982) In Cohen,P. and van Heyningen,S. (eds). Molecular Action of Toxins and Viruses. Elsevier Biomedical Press, pp. 219-331.
32. Remington,S., Wiegand,G. and Huber,R. (1982) J. Mol. Biol., 158, 111-152.
33. Revel,H.R. (1983) In Mathews,C.K., Kutter,E.M., Mosig,G. and Berget,P.B. (eds), Bacteriophage T4. American Society for Microbiology, Washington, DC, pp. 156-165.
34. Rossmann,M.G., Liljas,A., Bränden,C-I. and Bansazak,L.J. (1975) In Boyer,P.D. (ed.), The Enzymes. Academic Press, New York, Vol. II, pp. 61-102.
35. Rüger,W. (1978) Eur. J. Biochem., 88, 109-117.
36. Sack,J.S., Saper,M.A. and Quiocho,F.A. (1989a) J. Mol. Biol., 206, 17-191.
37. Sack,J.S. Trakhanov,S.D., Tsigannik,I.H. and Quiocho,F.A. (1989b) J. Mol. Biol., 206, 193-207.
38. Sharff,A.J., Rodseth,L.E., Spurlino,J.C. and Quiocho,F.A. (1992) Biochemistry, 31, 10657-10663.
39. Schultz,S.C., Shields,G.C. and Steitz,T.A. (1991) Science, 253, 1001-1007.
40. Skarzynski,T., Moody,P.C.E. and Wonacott,A.J. (1987) J. Mol. Biol., 193, 171-187.
41. Spurlino,J.C., Lu,G.-Y. and Quicho,F.A. (1991) J. Biol. Chem., 266, 5202-5219.
42. Tomaschewski,J., Gram,H., Crabb,J.W. and Rüger,W. (1985) Nucleic Acids Res., 13, 7551-7568.
43. Wang,B.C. (1985) Methods Enzymol., 115, 90-112.
44. Warner,H.R., Snustad,D.P., Jorgensen,S.E. and Koerner,J.F. (1970) J. Virol., 5, 700-708.
45. Warwicker,J. and Watson,H.C. (1982) J. Mol. Biol., 157, 671-679.
46. Westbrook,E.M. (1985) Methods Enzymol., 114, 187-196.
47. Wiegand,G. Remington,S., Deisenhofer,J. and Huber,R. (1984) J. Mol. Biol., 174, 205-219.
48. Wierenga,R.K., De Maeyer,M.C.H. and Hol,W.G.J. (1985) Biochemistry, 24, 1346-1357.
49. Wierenga,R.K. Terpstra,P. and Hol,W.G.J. (1986) J. Mol. Biol., 187, 101-107.
50. Winkler,M. and Rüger,W. (1993) Nucleic Acids Res., 21, 1500.
51. Winkler,F.K., Banner,D.W., Oefner,C., Tsernoglou,D., Brown,R.S., Heathman,S.P., Bryan,R.K., Martin,P.D., Petratos,K. and Wilson,K.S. (1993) EMBO J., 12, 1781-1795.
52. Wu,R. and Geiduschek,E.P. (1975) J. Mol. Biol., 96, 539-562.
53. Wyatt,G.R. and Cohen,S.S. (1952) Nature, 170, 1072-1073.
54. Zimmerman,S.B., Kornberg,S.R. and Kornberg,A. (1962) J. Biol. Chem., 237, 512-518.
55. Zou,J., Flocco,M.M. and Mowbray,S.L. (1993) J. Mol. Biol., 233, 739-752.