Long-term efficacy and safety of cyclosporine in renal-transplant recipients

New England Journal of Medicine

Volumn 331, Issue 6, 1994, Pages 358-363

  Burke, James F ^a   Pirsch, John D ^b   Ramos, Eleanor L ^c   Salomon, Daniel R ^d   Stablein, Donald M ^e   Van Buren, David H ^f   West, John C ^g  

^a THOMAS JEFFERSON UNIVERSITY HOSPITAL   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d UNIVERSITY OF FLORIDA   (United States)

^e EMMES CORPORATION   (United States)

^f Vanderbilt University Transplant Center   (United States)

^g GEISINGER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN;

ADULT; AGED; ARTICLE; CREATININE BLOOD LEVEL; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; FEMALE; GRAFT FAILURE; GRAFT REJECTION; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY DISEASE; KIDNEY FUNCTION; KIDNEY TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; NEPHROTIC SYNDROME; PRIORITY JOURNAL;

ADULT; CREATININE; CYCLOSPORINE; FEMALE; FOLLOW-UP STUDIES; GRAFT REJECTION; GRAFT SURVIVAL; HUMANS; KIDNEY; KIDNEY FAILURE; KIDNEY TRANSPLANTATION; MALE; RECURRENCE; RETROSPECTIVE STUDIES;

EID: 0027965108     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJM199408113310604     Document Type: Article

References (32)

1. Ponticelli C, Minetti L, Di Palo FQ, The Milan clinical trial with cyclosporine in cadaveric renal transplantation: a three-year follow-up. Transplantation 1988; 45: 908-913
2. Merion RM, White DJG, Thiru S, Evans DB, Calne RY Cyclosporine: five years' experience in cadaveric renal transplantation. N Engl J Med 1984; 310: 148-154
3. European Multicentre Trial Group. Cyclosporin in cadaveric renal transplantation: one-year follow-up of a multicentre trial. Lancet 1983; 2: 986-989
4. The Canadian Multicentre Transplant Study Group. A randomized clinical trial of cyclosporine in cadaveric renal transplantation: analysis at three years. N Engl J Med 1986; 314: 1219-1225
5. Calne RY Cyclosporin in cadaveric renal transplantation: 5-year follow-up of a multicentre trial. Lancet 1987; 2: 506-507
6. Mihatsch MJ, Thiel G, Ryffel B Histopathology of cyclosporine nephrotoxicity. Transplant Proc 1988; 20: Suppl 3: 759-771
7. Myers BD, Sibley R, Newton L, The long-term course of cyclosporine-associated chronic nephropathy. Kidney Int 1988; 33: 590-600
8. Greenberg A, Thompson ME, Griffith BJ, Cyclosporine nephrotoxicity in cardiac allograft patients — a seven-year follow-up. Transplantation 1990; 50: 589-593
9. Dieterle A, Gratwohl A, Nizze H, Chronic cyclosporine-associated nephrotoxicity in bone marrow transplant patients. Transplantation 1990; 49: 1093-1100
10. Mihatsch MJ, Bach JF, Coovadia HM, Cyclosporin-associated nephropathy in patients with autoimmune diseases. Klin Wochenschr 1988; 66: 43-47
11. Rocher LL, Milford EL, Kirkman RL, Carpenter CB, Strom TB, Tilney NL Conversion from cyclosporine to azathioprine in renal allograft recipients. Transplantation 1984; 38: 669-674
12. Versluis DJ, Wenting GJ, Derkx FHM, Schalekamp MADH, Jeekel J, Weimar W Who should be converted from cyclosporine to conventional immunosuppression in kidney transplantation, and why. Transplantation 1987; 44: 387-389
13. Delmonico FL, Conti D, Auchincloss H Jr, Long-term, low-dose cyclosporine treatment of renal allograft recipients: a randomized trial. Transplantation 1990; 49: 899-904
14. Kupin WL, Venkat KK, Norris C, Effective long-term immunosuppression maintained by low cyclosporine levels in primary cadaveric renal transplant recipients. Transplantation 1987; 43: 214-218
15. Brinker KR, Dickerman RM, Gonwa TA, A randomized trial comparing double-drug and triple-drug therapy in primary cadaveric renal transplants. Transplantation 1990; 50: 43-49
16. Lorber MI, Flechner SM, Van Buren CT, Sorensen K, Kerman RH, Kahan BD Cyclosporine toxicity: the effect of combined therapy using cyclosporine, azathioprine, and prednisone. Am J Kidney Dis 1987; 9: 476-484
17. Canafax DM, Min DI, Gruber SA, Immunosuppression for cadaveric renal allograft recipients: a risk-factor matched comparison of the Minnesota Randomized Trial with an antilymphoblast globulin, azathioprine, cyclosporine, and prednisone protocol. Clin Transplant 1989; 3: 110-119
18. Ponticelli C, Tarantino A, Montagnino G, A randomized trial comparing triple-drug and double-drug therapy in renal transplantation. Transplantation 1988; 45: 913-918
19. Wrenshall LE, Matas AJ, Canafax DM, An increased incidence of late acute rejection episodes in cadaver renal allograft recipients given azathioprine, cyclosporine, and prednisone. Transplantation 1990; 50: 233-237
20. Lewis RM, Janney RP, Golden DL, Stability of renal allograft function associated with long-term cyclosporine immunosuppressive therapy — five year follow-up. Transplantation 1989; 47: 266-272 [Erratum, Transplantation 1989;48:177.]
21. Ben-Maimon CS, Burke JF, Besarab A, Jarrell BE, Francos GC, Moyer SS Evidence against chronic progressive cyclosporine nephrotoxicity. Transplant Proc 1991; 23: 1260-1262
22. Salomon D, Brunson M, Vansickler J, A retrospective analysis of late renal graft function: correlation with mean cyclosporine levels and lack of evidence for chronic cyclosporine toxicity. Transplant Proc 1991; 23: 1018-1019
23. Amend W, Soskin T, Vincenti F, Long-term experience in primary cadaver renal transplants using cyclosporine. Clin Transplant 1990; 4: 341-346
24. Roth D, Fernandez J, Burke G, Long-term double (dbl.) vs. triple (trpl.) immunosuppressive therapy for cadaveric renal recipients (CADS). J Am Soc Nephrol 1991; 2: 815-815 abstract.
25. Salomon DR An alternative view minimizing the significance of cyclosporine nephrotoxicity and in favor of enhanced immunosuppression for long-term kidney transplant recipients. Transplant Proc 1991; 23: 2115-2118
26. Feutren G, Mihatsch MJ Risk factors for cyclosporine-induced nephropathy in patients with autoimmune diseases. N Engl J Med 1992; 326: 1654-1660
27. Almond PS, Gillingham KJ, Sibley R, Renal transplant function after ten years of cyclosporine. Transplantation 1992; 53: 316-323
28. Cecka JM, Cho YW, Terasaki PI Analyses of the UNOS Scientific Renal Transplant Registry at three years — early events affecting transplant success. Transplantation 1992; 53: 59-64
29. Cecka JM, Terasaki PI. Early rejection episodes. In: Terasaki PI, ed. Clinical transplants 1989. Los Angeles: UCLA Tissue Typing Laboratory, 1989:425-34.
30. Basadonna GP, Matas AJ, Gillingham KJ, Early versus late acute renal allograft rejection: impact on chronic rejection. Transplantation 1993; 55: 993-995
31. Almond PS, Matas A, Gillingham K, Risk factors for chronic rejection in renal allograft recipients. Transplantation 1993; 55: 752-757
32. Gulanikar AC, MacDonald AS, Sungurtekin U, Belitsky P The incidence and impact of early rejection episodes on graft outcome in recipients of first cadaver kidney transplants. Transplantation 1992; 53: 323-328