Specific Autoantibodies Directed Against Interferon-α in Pharmaceutically Prepared Human Immunoglobulin Preparations

Journal of Interferon Research

Volumn 14, Issue 4, 1994, Pages 159-160

  Ross, C ^a   Svenson, M ^a   Hansen, M B ^a   Veijlsgaard, G L ^a   Bendtzen, K ^a  

^a Rigshospitalet   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; ALPHA2A INTERFERON; IMMUNOGLOBULIN G; INTERFERON ANTIBODY;

ANTIBODY DETECTION; ANTIBODY TITER; ANTIGEN BINDING; AUTOIMMUNITY; COMPETITIVE INHIBITION; CONFERENCE PAPER; DRUG SCREENING; HUMAN; PRIORITY JOURNAL;

ANTIBODY SPECIFICITY; AUTOANTIBODIES; HUMAN; IMMUNOGLOBULIN G; INTERFERON-ALPHA;

EID: 0027963411     PISSN: 01978357     EISSN: 15577465     Source Type: Journal    
DOI: 10.1089/jir.1994.14.159     Document Type: Article

References (5)

1. CARUSO, A., BONFANTI, C, COLOMBRITA, D., et al. (1990). Natural antibodies to IFN-γ in man and their increase during viral infection. J. Immunol. 144, 685–690.
2. ROSS, C, HANSEN, M.B., SCHYBERG, T., and BERG, K. (1990). Autoantibodies to crude human leucocyte interferon (IFN), native human IFN-β, recombinant IFN-α-2b and human IFN-γ in healthy blood donors. Clin. Exp. Immunol. 82, 57–62.
3. HANSEN, M.B., SVENSON, M., and BENUTZEN, K. (1992). Serum-induced suppression of interferon (IFN) activity. Lack of evidence for the presence of specific autoantibodies to IFN-α in normal human sera. Clin. Exp. Immunol. 88, 559–562.
4. SVENSON, M., HANSEN, M.B., and BENUTZEN, K. (1993). Binding of cytokines to pharmaceutically prepared human immunoglobulin. J. Clin. Invest. 92, 2533–2539.
5. HANSEN, M.B., ROSS, C, and BERG, K. (1989). A sensitive antiviral neutralisation bioassay for measuring antibodies to interferons. J. Immunol. Meth. 127, 241–246.