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Volumn 35, Issue 31, 1994, Pages 5621-5624

Diastereoselective cathodic reduction of chiral phenylglyoxylamides

Author keywords

[No Author keywords available]

Indexed keywords

2 PYRROLIDONE DERIVATIVE; 4 ISOPROPYL 2 OXAZOLIDINONE; 5 METHYL 2 PYRROLIDONE; PHENYLGLYOXYLIC ACID; UNCLASSIFIED DRUG;

EID: 0027958897     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(00)77263-7     Document Type: Article
Times cited : (12)

References (19)
  • 5
    • 84913061229 scopus 로고    scopus 로고
    • d S. Torii, Electroorganic Synthesis, Methods and Applications, VCH Verlagsgesellschaft mbH, Weinheim
  • 9
    • 84913037820 scopus 로고    scopus 로고
    • For the preparation of amide 1 phenylglyoxylic acid 3 was activated by conversion into its mixed anhydride by reaction with pivaloyl chloride. Without isolation this anhydride was then treated with 4 in the presence of dimethylaminopyridine to afford amide 1 in 70% yield. 2 was obtained in 66% yield using phenylglyoxylic chloride, which was prepared from 3 and oxalyl chloride, and treating this with the lithium salt of 5, obtained from 5 and butyl lithium.
  • 14
    • 84913034491 scopus 로고    scopus 로고
    • 20 = −23.4 (c = 1 in ethanol)
  • 16
    • 84913034783 scopus 로고    scopus 로고
    • Optimizations of the geometry were carried out using the PM3 method in the MOPAC 7.0 program with the keywords PRECISE and GNORM = 0.1. Dr. J.J.P. Stewart, MOPAC 7.0, F.J. Seiler Research Laboratory, U.S. Airforce Academy, Colorado Springs.We thank T. Löhl, Organisch-Chemisches Institut der Universität Münster, for the PM3 calculations.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.