Dexamethasone and etoposide induce apoptosis in rat thymocytes from different phases of the cell cycle

Biochemical Pharmacology

Volumn 48, Issue 6, 1994, Pages 1073-1079

  Fearnhead, Howard O ^a   Chwalinski, Maciej ^a   Snowden, Roger T ^a   Ormerod, Michael G ^a   Cohen, Gerald M ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

bromodeoxyuridine; Percoll; proliferating and preapoptotic cells; quiescent

Indexed keywords

BROXURIDINE; DEXAMETHASONE; ETOPOSIDE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CELL TYPE; CONTROLLED STUDY; DRUG MECHANISM; FLOW CYTOMETRY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; THYMOCYTE;

ANIMAL; APOPTOSIS; BROMODEOXYURIDINE; CELL CYCLE; CELL SEPARATION; DEXAMETHASONE; ETOPOSIDE; MALE; RATS; RATS, INBRED F344; T-LYMPHOCYTES;

EID: 0027957109     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(94)90142-2     Document Type: Article

References (29)

1. Apoptosis and programmed cell death in immunity
2. Antibodies to DC3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures
3. Gene induction by γ irradiation leads to DNA fragmentation in lymphocytes
4. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation
5. Topisomerase II-reactive chemotherapeutic drugs induce apoptosis in thymocytes
6. A flow cytometric method for the separation and quantitation of normal and apoptotic thymocytes
7. Programmed cell death in the immune system
8. Hormone-induced cell death: purification and properties of thymocytes undergoing apoptosis after glucocorticoid treatment
9. Identification of a transitional preapoptotic population of thymocytes
10. Changes in nuclear chromatin precede internucleosomal DNA cleavage in the induction of apoptosis by etoposide
11. Bis(tri-n-butyltin)oxide induces programmed cell death (apoptosis) in immature rat thymocytes
12. Features of apoptotic cells measured by flow cytometry
13. Thymocyte apoptosis induced by p53-dependent and independent pathways
14. p53 is required for radiation-induced apoptosis in mouse thymocytes
15. Cyclosporin A inhibits activation induced cell death in T-cell hybridomas and thymocytes
16. Effects of the epipodophyllotoxin VP-16-213 on cell cycle traverse, DNA synthesis, and DNA strand size in cultures of human leukemic lymphoblasts
17. A new action for topoisomerase inhibitors
18. Changes in nuclear chromatin related to apoptosis or necrosis induced by the DNA topoisomerase II inhibitor fostriecin in MOLT-4 and HL-60 cells are revealed by altered DNA sensitivity to denaturation
19. Apoptotic cell death triggered by camptothecin or teniposide. The cell cycle specificity and effects of ionizing radiation
20. Camptothecin, teniposide, or 4'-(9-acridinylamino)-3methanesulfon-m-anisidide, but not mitoxantrone or doxorubicin, induces degradation of nuclear DNA in the S phase of HL-60 cells
21. Topoisomerase II in mitotic chromosome structure
22. Differential expression of DNA topoisomerases I and II during the eukaryotic cell cycle.
23. Proliferation-dependent regulation of topoisomerase II in cultured human cells
24. o cells and is prevented by inhibitors of proteases
25. A death in the life of p53
26. A mammalian cell cycle check point pathway utilizing p53 and GADD45 is defective in ataxiatelangiectasia
27. p53, guardian of the genome