Tamoxifen in the Prevention of Breast Cancer: Are the Risks Likely to Outweigh the Benefits?

Drug Safety

Volumn 10, Issue 1, 1994, Pages 1-4

  O’Brien, Mary ^a   Powles, Trevor J ^a  

^a ROYAL MARSDEN HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIESTROGEN; ANTINEOPLASTIC AGENT; TAMOXIFEN;

BREAST CANCER; CANCER CHEMOTHERAPY; CANCER PREVENTION; EDITORIAL; EYE TOXICITY; HEADACHE; LIVER TOXICITY; MENSTRUAL IRREGULARITY; NAUSEA; PRIORITY JOURNAL; RISK BENEFIT ANALYSIS; VAGINA DISCHARGE; VOMITING;

ANIMAL; BREAST NEOPLASMS; FEMALE; HUMAN; LIVER; TAMOXIFEN;

EID: 0027955220     PISSN: 01145916     EISSN: 11791942     Source Type: Journal    
DOI: 10.2165/00002018-199410010-00001     Document Type: Article

References (19)

1. Tamoxifen and liver damage
2. Ameta-analysis of studies of dietary fat and breast cancer risk
3. Tamoxifen-associated hepatocellular damage and agranulocytosis
4. Systemic treatment of early breast cancer by hormonal, cytotoxic, or immune therapy
5. Adjuvant tamoxifen in early breast cancer: occurrence of new primary cancers
6. Antitumour actions of keoxifene and tamoxifen in the N-nitrosemethylurea-induced rat mammary carcinoma model
7. Induction of covalent DNA adducts in rodents by tamoxifen
8. Tamoxifen and liver cancer. Correspondence
9. Tamoxifen retinopathy
10. Venous thrombosis as a side effect of tamoxifen treatment
11. A controlled study of the ocular effects of tamoxifen in conventional dosage in the treatment of breast carcinoma
12. Tamoxifen therapy in primary breast cancer. Biology, efficacy and side effects
13. High-grade endometrial carcinoma in tamoxifen-treated breast cancer patients
14. Tamoxifen retinopathy
15. Animal product consumption and subsequent fatal heart cancer risk among Seventh Day Adventists
16. Clear evidence that long-term low-dose tamoxifen treatment can induce ocular toxicity
17. LHRH agonists and the prevention of breast and ovarian cancer
18. Tamoxifen and the uterus and endometrium
19. Influence of the antioestrogen tamoxifen on normal breast tissue