Analysis of tumor necrosis factor promoter responses to ultraviolet light

Journal of Clinical Investigation

Volumn 93, Issue 1, 1994, Pages 56-62

  Bazzoni, Flavia ^a,b   Kruys, Véronique ^a,b,d   Shakhov, Alexander ^b,c   Jongeneel, C Victor ^b,c   Beutler, Bruce ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c LUDWIG INSTITUTE FOR CANCER RESEARCH   (Switzerland)

^d UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

lipopolisaccharide; mouse; NF B; signal transduction; transcription

Indexed keywords

CHLORAMPHENICOL ACETYLTRANSFERASE; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ARTICLE; CELL FUSION; CELL STRAIN 3T3; GENE INDUCTION; KERATINOCYTE; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; TRANSGENIC MOUSE; ULTRAVIOLET RADIATION;

EID: 0027952676     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI116984     Document Type: Article

References (33)

1. Piguet, P. F., G. E. Grau, C. Hauser, and P. Vassalli. 1991. Tumor necrosis factor is a critical mediator in hapten-induced irritant and contact hypersensitivity reactions. J. Exp. Med. 173:673-679.
2. Büscher, M., H. J. Rahmsdorf, M. Litfin, M. Karin, and P. Herrlich. 1988. Activation of the c-fos gene by UV and phorbol ester: different signal transduction pathways converge to the same enhancer element. Oncogene. 3:301-311.
3. Stein, B., H. J. Rahmsdorf, A. Steffen, M. Litfin, and P. Herrlich. 1989. UV-induced DNA damage is an intermediate step in UV-induced expression of human immunodeficiency virus type 1, collagenase, c-fos, and metallothionein. Mol. Cell. Biol. 9:5169-5181.
4. Morrey, J. D., S. M. Bourn, T. D. Bunch, M. K. Jackson, R. W. Sidwell, L. R. Barrows, R. A. Daynes, and C. A. Rosen. 1991. In vivo activation of human immunodeficiency virus type 1 long terminal repeat by UV type A (UV-A) light plus psoralen and UV-B light in the skin of transgenic mice. J. Virol. 65:5045-5051.
5. Shakhov, A. N., M. A. Collart, P. Vassalli, S. A. Nedospasov, and C. V. Jongeneel. 1990. κB-type enhancers are involved in lipopolysaccharide- mediated transcriptional activation of the tumor necrosis factor α gene in primary macrophages. J. Exp. Med. 171:35-47.
6. Han, J., T. Brown, and B. Beutler. 1990. Endotoxin-responsive sequences control cachectin/tumor necrosis factor biosynthesis at the translational level. J. Exp. Med. 171:465-475.
7. Kock, A., T. Schwarz, R. Kirnbauer, A. Urbanski, P. Perry, J. C. Ansel, and T. A. Luger. 1990. Human keratinocytes are a source for tumor necrosis factor α: evidence for synthesis and release upon stimulation with endotoxin or ultraviolet light. J. Exp. Med. 172:1609-1614.
8. Kruys, V., P. Thompson, and B. Beutler. 1993. Extinction of the tumor necrosis factor locus, and of genes encoding the lipopolysaccharide signaling pathway. J. Exp. Med. 177:1383-1390.
9. Beutler, B., and T. Brown. 1991. A CAT reporter construct allows ultrasensitive estimation of TNF synthesis, and suggests that the TNF gene has been silenced in non-macrophage cell lines. J. Clin. Invest. 87:1336-1344.
10. Han, J., G. Huez, and B. Beutler. 1991. Interactive effects of the TNF promoter and 3′-untranslated regions. J. Immunol. 146:1843-1848.
11. Shakhov, A. N., R. L. Turetskaya, D. V. Kuprash, S. A. Nedospasov, M. A. Collart, C. Drouet, and C. V. Jongeneel. 1990. Sequences involved in the regulation of TNF gene expression. In Molecular and Cellular Biology of Cytokines. Wiley-Liss, Inc., New York. 25-30.
12. Giroir, B. P., T. Brown, and B. Beutler. 1992. Constitutive synthesis of tumor necrosis factor in the thymus. Proc. Natl. Acad. Sci. USA. 89:4864-4868.
13. Giroir, B. P., K. Peppel, M. Silva, and B. Beutler. 1992. The biosynthesis of tumor necrosis factor during pregnancy: studies with a CAT reporter transgene and TNF inhibitors. Eur. Cytokine Network. 3:533-538.
14. Chen, C., and H. Okayama. 1987. High-efficiency transformation of mammalian cells by plasmid DNA. Mol. Cell. Biol. 7:2745-2752.
15. Gorman, C. M., L. F. Moffat, and B. H. Howard. 1982. Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol. Cell. Biol. 2:1044-1051.
16. Kawakami, M., and A. Cerami. 1981. Studies of endotoxin-induced decrease in lipoprotein lipase activity. J. Exp. Med. 154:631-639.
17. Favaloro, J., R. Treisman, and R. Kamen. 1980. Transcription maps of polyoma virus-specific RNA: analysis by two-dimensional nuclease S1 gel mapping. Methods Enzymol. 65:718.
18. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
19. Caput, D., B. Beutler, K. Hartog, S. Brown-Shimer, and A. Cerami. 1986. Identification of a common nucleotide sequence in the 3′-untranslated region of mRNA molecules specifying inflammatory mediators. Proc. Natl. Acad. Sci. USA. 83:1670-1674.
20. Cseh, K., and B. Beutler. 1989. Alternative cleavage of the cachectin/TNF propeptide results in a larger, inactive form of secreted protein. J. Biol. Chem. 264:16256-16260.
21. Piguet, P. F. 1992. Keratinocyte-derived tumor necrosis factor and the physiopathology of the skin. Springer Semin. Immunopath. 13:345-354.
22. Yoshikawa, T., and J. W. Streilein. 1990. Genetic basis of the effects of ultraviolet light B on cutaneous immunity. Evidence that polymorphism at the TnFa and Lps loci governs susceptibility. Immunogenetics. 32:398-405.
23. Chia, J. K. S., and E. J. McManus. 1990. In vitro tumor necrosis factor induction assay for analysis of febrile toxicity associated with amphotericin B preparations. Antimicrob. Agents Chemother. 34:906-908.
24. Shennan, M. L., R. Datta, D. E. Hallahan, R. R. Wechselbaum, and D. W. Kufe. 1991. Regulation of tumor necrosis factor gene expression by ionizing radiation in human myeloid leukemia cells and peripheral blood monocytes. J. Clin. Invest. 87:1794-1997.
25. Browning, J. L., A. Ngam-ek, P. Lawton, J. DeMarinis, R. Tizard, E. P. Chow, C. Hesslon, B. O'Brine-Greco, S. F. Foley, and C. F. Ware. 1993. Lymphotoxin β, a novel member of the TNF family that forms a heteromeric complex with lymphotoxin on the cell surface. Cell. 72:847-856.
26. Jacob, C. O., and H. O. McDevitt. 1988. Tumour necrosis factor-alpha in murine autoimmune 'lupus' nephritis. Nature (Lond.). 331:356-358.
27. Satoh, J., H. Seino, T. Abo, S. Tanaka, S. Shintani, S. Ohta, K. Tamura, T. Sawai, T. Nobunaga, T. Oteki, K. Kumagai, and T. Toyota. 1989. Recombinant human tumor necrosis factor a suppresses autoimmune diabetes in nonobese diabetic mice. J. Clin. Invest. 84:1345-1348.
28. Jacob, C. O., S. Aiso, S. A. Michie, H. O. McDevitt, and H. Acha-Orbea. 1990. Prevention of diabetes in nonobese diabetes mice by tumor necrosis factor (TNF): similarities between TNF-alpha and interleukin 1. Proc. Natl. Acad. Sci. USA. 87:968-972.
29. Held, W., H. R. MacDonald, I. L. Weissman, M. W. Hess, and C. Mueller. 1990. Genes encoding tumor necrosis factor α and granzyme A are expressed during development of autoimmune diabetes. Proc. Natl. Acad. Sci. USA. 87:2239-2243.
30. Jacob, C. O., Z. Fronek, G. D. Lewis, M. Koo, J. A. Hansen, and H. O. McDevitt. 1990. Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor α: relevance to genetic predisposition to systemic lupus erythematosus. Proc. Natl. Acad. Sci. USA. 87:1233-1237.
31. Reinertsen, J. L., J. H. Klippel, A. H. Johnson, A. D. Steinberg, J. L. Decker, and D. L. Mann. 1978. B-lymphocyte alloantigens associated with systemic lupus erythematosus. N. Engl. J. Med. 299:515-518.
32. Knight, J. G., and D. D. Adams. 1978. Three genes for lupus nephritis in NZB × NZW mice. J. Exp. Med. 147:1653-1660.
33. 1 mice. J. Exp. Med. 165:1237-1251.