Platelet membrane-mediated coagulation protease complex assembly

Trends in Cardiovascular Medicine

Volumn 4, Issue 6, 1994, Pages 271-278

  Ahmad, Syed S ^a   Walsh, Peter N ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; ANTICOAGULANT AGENT; BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 11; BLOOD CLOTTING FACTOR 5A; BLOOD CLOTTING FACTOR 7A; BLOOD CLOTTING FACTOR 8A; BLOOD CLOTTING FACTOR 9; BLOOD CLOTTING FACTOR 9A; CALCIMYCIN; COLLAGEN; HEPARIN; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLSERINE; PROTEASOME; PROTEIN C; PROTHROMBIN; PROTHROMBIN A; RECEPTOR PROTEIN; SEROTONIN; THROMBIN; THROMBOCYTE FACTOR 4; THROMBOCYTE RECEPTOR; THROMBOMODULIN; THROMBOPLASTIN;

ANIMAL EXPERIMENT; BLOOD CLOTTING; CORONARY ARTERY THROMBOSIS; DOSE RESPONSE; DRUG DESIGN; ENZYME INDUCTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; RECEPTOR AFFINITY; RECEPTOR DENSITY; SHORT SURVEY; THROMBOCYTE MEMBRANE;

EID: 0027939190     PISSN: 10501738     EISSN: None     Source Type: Journal    
DOI: 10.1016/1050-1738(94)90031-0     Document Type: Short Survey

References (45)

1. Platelet receptor-mediated factor X activation by factor IXa: high-affinity factor IXa receptors induced by factor VIII are deficient on platelets in Scott syndrome
2. Comparative interactions of factor IX and factor IXa with human platelets
3. Platelet receptor occupancy with factor IXa promotes factor X activation
4. Comparative platelet binding and kinetic studies with normal and variant factor IXa molecules
5. The role of first growth factor domain of human factor IXa in binding to platelets and in factor-X activation
6. Components and assembly of the factor-X activating complex
7. High-affinity, specific factor-IXa binding to platelets is indicated in part by residues 1–3
8. Active site-blocked factor IXa prevents intravascular thrombus formation in the coronary vasculature without inhibiting extravascular coagulation in a canine thrombosis model
9. Active site-blocked factor Xa prevents thrombus formation in the coronary vasculature in parallel with inhibition of extravascular coagulation in a canine thrombosis model
10. Subcellular localization and secretion of factor V from human platelets
11. Reconstitution of rabbit thrombomodulin into phospholipid vesicles
12. Factor IX
13. Blood coagulation factors at phospholipid surfaces
14. Treatment of Venous Thromboembolism
15. Factor Va-dependent binding of factor Xa to human platelets
16. Activation of coagulation factor V by a platelet protease
17. 2+ to blood coagulation factor X
18. Activation-dependent appearance of a platelet protein that recognizes factor IXa
19. The formation of thrombin on the platelet surface
20. Cofactor Proteins in the Assembly and Expression of Blood Clotting Enzyme Complexes
21. Thromboregulation: multicellular modulation of platelet reactivity in hemostasis and thrombosis
22. Thrombolytic therapy: current status
23. Functional difference between intrinsic and extrinsic coagulation pathways: kinetics of factor-X activation on human monocytes and alveolar macrophages
24. Interaction of coagulation factor Xa with human platelets
25. Properties of the factor Xa binding site on human platelets
26. 35S-labeled recombinant factor VIII to activated and inactivated human platelets
27. Kinetics of coagulation factor X activation by platelet-bound factor IXa
28. The role of γ-carboxyglutamic acid residues in the binding of factor IXa to platelets and in factor-X activation
29. The role of phospholipids and factor Va in the prothrombinase complex
30. The role of activated human platelets in prothrombin and factor X activation
31. Factor X binding site on activated human platelets [abst]
32. Appraisal of various thrombolytic agents in the treatment of acute myocardial infection
33. The binding of factor IXa to cultured bovine aortic endothelial cells
34. Protection of factor Xa from neutralization by the heparin-antithrombin complex
35. Clinical trials of platelet receptor inhibitors
36. Interaction of coagulation factor V and factor Va with platelets
37. Coordinate binding of factor Va and factor Xa to the unstimulated platelet.
38. Proteolytic alterations of factor Va bound to platelets
39. Functional prothrombinase complex assembly on isolated monocytes and lymphocytes
40. The role of phospholipid and factor VIIIa in the activation of bovine factor X
41. Different requirements for intrinsic factor Xa-forming activity and platelet factor 3 activity and their relationship to platelet aggregation and secretion
42. Platelet-mediated trigger mechanisms in the contact phase of blood coagulation
43. Platelet-coagulant protein interactions
44. The role of platelets in intrinsic factor Xa formation
45. Kinetics of factor IX activation via the extrinsic pathway dependence of Km on tissue factor