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Current Opinion in Immunology
Volumn 6, Issue 5, 1994, Pages 715-721
Recent developments in the radioimmunotherapy of cancer
Author keywords

[No Author keywords available]
Indexed keywords

MONOCLONAL ANTIBODY; RADIOISOTOPE;
EID: 0027937851     PISSN: 09527915     EISSN: None     Source Type: Journal    
DOI: 10.1016/0952-7915(94)90074-4     Document Type: Article
Times cited : (24)
References (37)
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    • Physiological Barriers to Delivery of Monoclonal Antibodies and Other Macromolecules in Tumors
    • (suppl)
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  • 4
    • 0026501316 scopus 로고
    • Spatial Distribution of Tumor-Specific Monoclonal Antibodies in Human Melanoma Xenografts
    • (1992) Cancer Res , vol.52 , pp. 367-376
    • Shockley1    Lin2    Nagy3
  • 5
    • 0027484445 scopus 로고
    • Radiolabeled-Antibody Therapy of B-Cell Lymphoma with Autologous Bone Marrow Support
    • of outstanding interest, The authors examine the biodistribution of several mAbs, and then demonstrate the feasibility and efficacy of a single high dose of radioimmunotherapy with autologous marrow rescue.
    • (1993) New Engl J Med , vol.329 , pp. 1219-1224
    • Press1    Eary2    appelbaum3    Martin4    Badger5    Nelp6    Glenn7    Butchko8    Fisher9    Porter10
  • 9
    • 0026599425 scopus 로고
    • A Quantitative Analysis of Tumor Specific Monoclonal Antibody Uptake by Human Melanoma Xenografts: Effects of Antibody Immunological Properties and Tumor Antigen Expression Levels
    • (1992) Cancer Res , vol.52 , pp. 357-366
    • Shockley1    Lin2    Sung3
  • 12
    • 0026527930 scopus 로고
    • Improved Delivery of Radiolabeled Anti-Bt Monoclonal Antibody to Raji Lymphoma Xenografts by Predosing with Unlabeled Anti-B1 Monoclonal Antibody
    • (1992) Cancer Res , vol.52 , pp. 637-642
    • Buchsbaum1    Wahl2    Glenn3    Normolle4    Kaminski5
  • 13
    • 0020694773 scopus 로고
    • Kinetic and Catabolic Considerations of Monoclonal Antibody Targeting in Erythroleukemic Mice
    • (1983) Cancer Res , vol.43 , pp. 265-272
    • Scheinberg1    Strand2
  • 15
    • 0026442158 scopus 로고
    • Plasmapheresis in Radioimmunotherapy of Micrometastases: A Mathematical Modeling and Dosimetrical Analysis
    • (1992) J Nucl Med , vol.33 , pp. 2167-2179
    • Sgouros1
  • 25
    • 0027284849 scopus 로고
    • Experimental Radioimmunotherapy
    • of interest, This paper extensively reviews pre-clinical radioimmunotherapy studies with human tumor spheroids and human tumor xenografts in experimental animals.
    • (1993) Med Phys , vol.20 , pp. 551-567
    • Buchsbaum1    Langmuir2    Wessels3
  • 30
    • 0027219075 scopus 로고
    • Adjuvant Therapy of Ovarian Cancer with Radioactive Monoclonal Antibody
    • of interest, This study suggests that ovarian cancer patients who achieve a complete remission with conventional therapy may benefit from further treatment with intraperitoneal radiolabeled mAbs.
    • (1993) Br J Cancer , vol.68 , pp. 403-406
    • Hird1    Maraveyas2    Snook3    Dhokia4    Soutter5    Meares6    Stewart7    Mason8    Lambert9    Epenetos10
  • 32
    • 0028344048 scopus 로고
    • Effect of Lym-1 Radioimmunoconjugate on Refractory Chronic Lymphocytic Leukemia
    • of interest, This study shows that treatment with a radiolabeled mAb, Lym-1, reative with B-cells, is able to reduce adenopathy and circulating lymphocytes in patients with chronic lymphocytic leukemia.
    • (1994) Cancer , vol.73 , pp. 1425-1432
    • De Nardo1    Lewis2    DeNardo3    O'Grady4
  • 33
    • 0027443336 scopus 로고
    • Phase 1 Dose-Escalation Trial of Iodine 131-Labeled Monoclonal Antibody OKB7 in Patients With Non-Hodgkin's Lymphoma
    • of interest, Although tumors could be visualized in only 45% of patients, a significant number of mixed tumor responses were observed with minimal toxicity after treatment with this radioiodinated restricted B-cell mAb.
    • (1993) J Clin Oncol , vol.11 , pp. 2021-2029
    • Czuczman1    Straus2    Divgi3    Graham4    Garin-Chesa5    Finn6    Myers7    Old8    Larson9    Scheinberg10
  • 36
    • 0027499283 scopus 로고
    • Dose-Escalation Trial of M195 Labeled With Iodine 131 for Cytoreduction and Marrow Ablation in Relapsed or Refractory Myeloid Leukemias
    • 131I-labeled anti-CD33 mAb could specifically target bone marrow and kill up to 1 kg of myeloid leukemia cells without significant extramedullary toxicity.
    • (1993) J Clin Oncol , vol.11 , pp. 294-303
    • Schwartz1    Lovett2    Redner3    Finn4    Graham5    Divgi6    Dantis7    Gee8    Andreeff9    Old10
  • 37
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    • A Phase IB Trial of Humanized Monoclonal Antibody M195 (Anti-CD33) in Myloid Leukemia: Specific Targeting Without Immunogenicity
    • of outstanding interest, This is the first trial in leukemia using a fully humanized mAb, anti-CD33 M195. Specific bone marrow targeting was seen with minimal toxicity, as had been observed with murine M195. Immunogenicity was not demonstrated.
    • (1994) Blood , vol.83 , pp. 1760-1768
    • Caron1    Jurcic2    Scott3    Finn4    Divgi5    Graham6    Jureidini7    Sgouros8    Tyson9    Old10

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.