Risk and benefit of low systemic heparinization during open heart operations

The Annals of Thoracic Surgery

Volumn 58, Issue 2, 1994, Pages 391-398

  Segesser, Ludwig K von ^a   Weiss, Branko M ^a   Pasic, Miralem ^a   Garcia, Eligio ^a   Turina, Marko I ^a  

^a University Hospital ^*  (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

HEPARIN;

ADULT; AGED; ARTICLE; BLEEDING; CORONARY ARTERY SURGERY; HUMAN; MAJOR CLINICAL STUDY; OPEN HEART SURGERY; PRIORITY JOURNAL; RISK; THROMBOSIS;

BLOOD COAGULATION; BLOOD LOSS, SURGICAL; BLOOD TRANSFUSION; CARDIAC SURGICAL PROCEDURES; CARDIOPULMONARY BYPASS; COMPARATIVE STUDY; FEMALE; HEPARIN; HOSPITAL MORTALITY; HUMAN; MALE; MIDDLE AGE; POSTOPERATIVE COMPLICATIONS; PROSPECTIVE STUDIES; SUPPORT, NON-U.S. GOV'T; SURFACE PROPERTIES;

EID: 0027936510     PISSN: 00034975     EISSN: None     Source Type: Journal    
DOI: 10.1016/0003-4975(94)92213-6     Document Type: Article

References (25)

1. JA Young CT Kisker DB Doty Adequate anticoagulation during cardiopulmonary bypass determined by activated clotting time and appearance of fibrin monomer Ann Thorac Surg 26 1978 231 240
2. GP Gravlee WS Haddon HK Rothberger Heparin dosing and monitoring for cardiopulmonary bypass J Thorac Cardiovasc Surg 99 1990 518 527
3. PFG Cardoso F Yamazaki S Keshavjee A reevaluation of heparin requirements for cardiopulmonary bypass J Thorac Cardiovasc Surg 101 1991 153 160
4. S Metz AS Keats Low activated coagulation time during cardiopulmonary bypass does not increase postoperative bleeding Ann Thorac Surg 49 1990 440 444
5. VL Gott JD Whiffert RC Datton Heparin bonding on colloidal graphite surface Science 142 1963 1297 1298
6. O Larm R Larson P Olsson A new non-thrombogenic surface prepared by selective covalent binding heparin via a modified reducing terminal residue Biomater Med Devices Artif Organs 11 1983 161 173
7. SW Kim CD Ebert JY Lin JC McRen Nonthrombogenic polymers—pharmaceutical approaches ASAIO J 6 1985 76 87
8. LK Von Segesser MI Turina Heparin coated hollow-fiber oxygenetor without systemic heparinization in comparison to classic bubble and membrane oxygenators AmSECT Proceedings Anaheim, CA March 11–14, 1988 76 83
9. LK Von Segesser MI Turina Cardiopulmonary bypass without systemic heparinization: performance of heparin coated oxygenators in comparison to classic membrane and bubble oxygenators J Thorac Cardiovasc Surg 98 1989 386 396
10. LK Von Segesser BM Weiss MI Turina Perfusion with heparin coated equipment: potential for clinical use 1st ed Semin Thorac Cardiovasc Surg 2 1990 373 380
11. L Bindslev J Eklund O Norlander Treatment of acute respiratory failure by extracorporeal carbon dioxide elimination performed with a surface heparinized artificial lung Anesthesiology 67 1987 117 120
12. LK Von Segesser BM Weiss F Garcia Reduced blood loss and transfusion requirements with low systemic heparinization: preliminary clinical results in coronary artery revascularization Eur J Thorac Cardiovasc Surg 4 1990 639 643
13. LK Von Segesser BM Weiss E Garcia MI Turina Reduction and elimination of systemic heparinization during cardiopulmonary bypass J Thorac Cardiovasc Surg 103 1992 790 799
14. TE Mollnes V Videm O Götze Formation of C5a during cardiopulmonary bypass: Inhibition by precoating with heparin Ann Thorac Surg 52 1991 92 97
15. MJ P'radhan JS Fleming UU Nkere Clinical experience with heparin-coated cardiopulmonary bypass circuits Perfusion 6 1991 233 242
16. YJ Gu W van Oeveren KWHJ van der Kamp Heparin-coating of extracorporeal circuits reduces thrombin formation in patients undergoing cardiopulmonary bypass Perfusion 6 1991 221 225
17. V Videm JL Svennevig E Fosse Reduced complement activation with heparin-coated oxygenator and tubings in coronary bypass operations J Thorac Cardiovasc Surg 103 1992 806 813
18. YJ Gu W van Oeveren C Akkerman Heparin-coated circuits reduce the inflammatory response to cardiopulmonary bypass Ann Thorac Surg 55 1993 917 922
19. LK Von Segesser E Garcia MI Turina Perfusion without systemic heparinization for rewarming in accidental deep hypothermia Ann Thorac Surg 52 1991 560 561
20. RD Dowling ME Brown RO Whittington Clinical cardiopulmonary bypass without systemic heparinization Ann Thorac Surg 56 1993 1176 1178
21. LK Von Segesser BM Weiss E von Felten MI Turina Coagulation patterns in perfusion with low systemic heparinization J Extracorp Technol 23 1992 80 85
22. Kunz M, von Segesser LK, Turina MI. Reduced coagulation disorders, blood trauma and immunologic response after cardiopulmonary bypass with heparin coated equipment. J Cardiovasc Surg (in press).
23. LH Edmunds Blood-surface interaction during cardiopulmonary bypass J Cardiovasc Surg 8 1993 404 410
24. JW Borowiec A Bylock J van der Linden S Thelin Heparin coating reduces blood cell adhesion to arterial filters during coronary bypass: A clinical study Ann Thorac Surg 55 1993 1540 1545
25. LK Von Segesser DD Gyurech JJ Schilling K Marquardt MI Turina Can protamine be used during perfusion with heparin surface coated equipment? ASAIO J 39 1993 M190 M194