Qualitative mapping of cerebral blood flow and functional localization with echo-planar MR imaging and signal targeting with alternating radio frequency

Radiology

Volumn 192, Issue 2, 1994, Pages 513-520

  Edelman, Robert R ^a   Siewert, Bettina ^a,b   Darby, David G ^a   Thangaraj, Venketasen ^a   Nobre, Anna C ^a   Mesulam, M Marsel ^a   Warach, Steven ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b UNIVERSITY OF BONN   (Germany)

Author keywords

Cerebral blood vessels, flow dynamics; Magnetic resonance (MR), echo planar; Magnetic resonance (MR), vascular studies

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN BLOOD FLOW; HUMAN; HYPERCAPNIA; MOTOR CORTEX; NONHUMAN; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RADIOFREQUENCY; SENSORIMOTOR FUNCTION; SWINE; VISUAL CORTEX;

EID: 0027936294     PISSN: 00338419     EISSN: None     Source Type: Journal    
DOI: 10.1148/radiology.192.2.8029425     Document Type: Article

References (25)

1. Raichle ME, Grubb RL, Gado MH, Eichling JO, Ter-Pogossian EM. Correlation between regional cerebral blood flow and oxidative metabolism: in vivo studies in man. Arch Neurol 1976; 33:523-526.
2. Phelps ME, Mazziotta JC. Positron emission tomography: human brain function and biochemistry. Science 1985; 228:799-809.
3. Posner MI, Petersen SE, Fox PT, Raichle ME. Localization of cognitive operations in the human brain. Science 1988; 240: 1627-1631.
4. Neil JJ. The validation of freely diffusible tracer methods with nuclear magnetic resonance detection for measurement of blood flow. Magn Reson Med 1991; 19:299-304.
5. Ackerman JJH, Ewy CS, Becker NN, Shalwitz RA. Deuterium nuclear magnetic resonance measurements of blood flow and tissue perfusion employing 2H20 as a freely diffusible tracer. Proc Natl Acad Sci 1987; 84:4099-4102.
6. Belliveau JW, Rosen BR, Kantor HL, et al. Functional cerebral imaging by susceptibility-contrast NMR. Magn Reson Med 1990; 14:538-546.
7. Rosen BR, Belliveau JW, Chien D. Perfusion imaging by nuclear magnetic resonance. Magn Reson Q 1989; 5:263-281.
8. Detre JA, Leigh JS, Williams DS, Koretsky AP. Perfusion imaging. Magn Reson Med 1992; 23:37-45.
9. Edelman RR, Mattle HP, Atkinson DJ, et al. Cerebral blood flow: assessment with dynamic contrast-enhanced T2*-weighted MR imaging at 1.5 T. Radiology 1990; 176: 211-220.
10. Belliveau JW, Kennedy DN Jr, Mckinstry RC, et al. Functional mapping of the human visual cortex by magnetic resonance imaging. Science 1991; 254:716-719.
11. Ogawa S, Tank DW, Menon R, et al. Intrinsic signal changes accompanying sensory stimulation: functional brain mapping with magnetic resonance imaging. Proc Natl Acad Sci USA 1992; 89:5951-5955.
12. Kwong KK, Belliveau JW, Chesler DA, et al. Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation. Proc Natl Acad Sci USA 1992; 89:5675-5679.
13. Bandettini PA, Wong EC, Hinks RS, Tikofsky RS, Hyde JS. Time-course echo-planar imaging of human brain function during task activation. Magn Reson Med 1992; 25:390-397.
14. Hajnal JV, Oatridge A, Schwieso J, Cowan FM, Young IR, Bydder GM. Cautionary remarks on the role of veins in the variability of functional imaging experiments (abstr). In: Proceedings of the Society of Magnetic Resonance in Medicine 1993. Berkeley, Calif: Society of Magnetic Resonance in Medicine, 1993; 166.
15. Fox PT, Fox JM, Raichle ME, Burde RM. The role of cerebral cortex in the generation of voluntary saccades: a positron emission tomography study. J Neurophysiol 1985; 54:348-369.
16. Edelman RR, Siewert B, Adamis M, Gaa J, Laub G, Wielopolski P. Signal targeting with alternating radiofrequency (STAR) sequences: application to MR angiography. Magn Reson Med 1994; 31:233-238.
17. Sardashti M, Schwartzberg DG, Stomp GP, Dixon WT. Spin-labeling angiography of the carotids by presaturation and simplified adiabatic inversion. Magn Reson Med 1990; 15:192-200.
18. Dixon WT, Du LN, Faul DD, Gado M, Rossnick S. Projection angiograms of blood labeled by adiabatic fast passage. Magn Reson Med 1986; 3:454-462.
19. Wang SJ, Nishimura DG, Macovski A. Fast angiography using selective inversion recovery. Magn Reson Med 1992; 23:109-121.
20. Roberts DA, Detre JA, Bolinger L, Insko EK, Leigh JS. Quantitative magnetic resonance imaging of human brain perfusion at 1.5 T using steady-state inversion of arterial water. Proc Natl Acad Sci 1994; 91:33-37.
21. Wolff SD, Balaban RS. Magnetization transfer contrast (MTC) and tissue water proton relaxation in vivo. Magn Reson Med 1988; 10:135-144.
22. Gur RC, Gur RE, Obrist WD, et al. Sex and handedness in cerebral blood flow during rest and cognitive activity. Science 1982; 217:659-661.
23. Gur RC, Gur RE, Obrist WD, Skolnick BE, Reivich M. Age and regional cerebral blood flow at rest and during cognitive activity. Arch Gen Psychiatry 1987; 44:617-621.
24. Lagrèze HL, Hartmann A. Data analysis in behavioral cerebral blood flow activation studies using xenon-133 clearance. Stroke 1993; 24:387-391.
25. Hajnal JV, Myers R, Oatridge A, Bydder GM, Young IR. Evidence for stimulus-correlated motion in functional neuroimaging experiments. (abstr). JMRI 1994; 4(P):60.