Crocacin, a new electron transport inhibitor from chondromyces crocatus (myxobacteria). Production, isolation, physico-chemical and biological properties

The Journal of Antibiotics

Volumn 47, Issue 8, 1994, Pages 881-886

  Kunze, Brigitte ^a   Reichenbach, Hans ^a   Jansen, Rolf ^b   Höfle, Gerhard ^b  

^a HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^b Natural Product Chemistry   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CROCACIN; CYTOCHROME B; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ARTICLE; BACTERIAL GROWTH; CONTROLLED STUDY; DRUG ACTIVITY; DRUG ISOLATION; ELECTRON TRANSPORT; GRAM POSITIVE BACTERIUM; MOULD; MYXOCOCCALES; NONHUMAN; PRIORITY JOURNAL; SUBMITOCHONDRIAL PARTICLE; YEAST;

ANTIBIOTICS; CHEMISTRY, PHYSICAL; ELECTRON TRANSPORT; FERMENTATION; GRAM-POSITIVE BACTERIA; MICROBIAL SENSITIVITY TESTS; MYXOCOCCALES; POLYENES;

EID: 0027932849     PISSN: 00218820     EISSN: 18811469     Source Type: Journal    
DOI: 10.7164/antibiotics.47.881     Document Type: Article

References (9)

1. Jansen, R.; B. Kunze, H. Relchenbach & G. Höfle: Crocacin, a novel antibiotic from Chondromyces crocatus. Liebigs Ann. Chem., in preparation.
2. Jacobi, C.: DSM, German Collection of Microorganisms: personal communication.
3. Pfennig, N.; Rhodopseudomonas globiformis, Sp. n., a new species of the rhodospirillaceae. Arch. Microbiol. 100: 197~206, 1974.
4. Thierbach, G. & H. Reichenbach: Myxothiazol, a new inhibitor of the cytochrome bc1 segment of the respiratory chain. Biochim. Biophys. Acta 638: 282~289, 1981.
5. Thierbach, G.; B. Kunze, H. Reichenbach & G. Höfle: The mode of action of stigmatellin, a new inhibitor of the cytochrome b-c1 segment of the respiratory chain. Biochim. Biophys. Acta 765: 227~235, 1984.
6. Gerth, K.; R. Jansen, G. Reifenstahl, G. Höfle, H. Irschik, B. Kunze, H. Reichenbach & G. Thierbach: The myxalamids, new antibiotics from Myxococcus xanthus (Myxobacterales) I. Production, physico-chemical and biological properties, and mechanism of action. J. Antibiotics 36: 1150~1156, 1983.
7. Pridzun, L.; B. Kunze & H. Reichenbach: The mechanism of action of the aurachins, new electron transport inhibitors from myxobacteria. Biochim. Biophys. Acta, submitted.
8. Kunze, B.; R. Jansen, L. Pridzun, E. Jurkiewicz, G. Hunsmann, G. Höfle & H. Reichenbach: Phenoxan, a new oxazole-pyrone from myxobacteria: Production, antimicrobial activity and its inhibition of the electron transport in complex I of the respiratory chain. J. Antibiotics 45: 1549~1552, 1992.
9. Kunze, B.; R. Jansen, L. Pridzun, E. Jurkiewicz, G. Hunsmann, G. Höfle & H. Reichenbach: Thiangazole, a new thiazoline antibiotic from Polyangium spec, (myxobacteria): Production, antimicrobial activity and mechanism of action. J. Antibiotics 46: 1752~1755, 1993.