Doxorubicin-induced oxygen free radical formation in sensitive and doxorubicin-resistant variants of rat glioblastoma cell lines

FEBS Letters

Volumn 326, Issue 1-3, 1993, Pages 302-305

  Benchekroun, M Nabil ^a,b   Sinha, Birandra K ^b   Robert, Jacques ^a,c  

^a UNIVERSITÉ DE BORDEAUX   (France)

^b NATIONAL CANCER INSTITUTE   (United States)

^c Lab de Biochim et Pharmacologie   (France)

Author keywords

Anthracycline; Anticancer drug; Electron spin resonance spectroscopy; Free radical; Lipid peroxidation; Redox activation

Indexed keywords

5,5 DIMETHYL 1 PYRROLINE 1 OXIDE; 5,5-DIMETHYL-1-PYRROLINE-1-OXIDE; AMINE OXIDE; CATALASE; DOXORUBICIN; FREE RADICAL; HYDROXIDE; HYDROXYL RADICAL; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE;

ANIMAL; ARTICLE; CELL CULTURE; DRUG RESISTANCE; ELECTRON SPIN RESONANCE; GLIOMA; METABOLISM; RAT; SPIN LABELING;

ANIMALS; CATALASE; CYCLIC N-OXIDES; DOXORUBICIN; DRUG RESISTANCE; ELECTRON SPIN RESONANCE SPECTROSCOPY; FREE RADICALS; GLIOMA; HYDROXIDES; HYDROXYL RADICAL; RATS; REACTIVE OXYGEN SPECIES; SPIN LABELS; SUPEROXIDE DISMUTASE; TUMOR CELLS, CULTURED;

EID: 0027915281     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-5793(93)81815-H     Document Type: Article

References (15)

1. An Electron Spin Resonance Study of the Spin Adducts of OH and HO2Radicals with Nitrones in the Ultraviolet Photolysis of Aqueous Hydrogen Peroxide Solutions