Structure and Modulation of Na+ and Ca2+ Channels

Annals of the New York Academy of Sciences

Volumn 707, Issue 1, 1993, Pages 1-19

  CATTERALL, WILLIAM A ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL; COMPLEMENTARY DNA; PROTEIN KINASE C; SODIUM CHANNEL; TETRODOTOXIN; VOLTAGE GATED CHANNEL FORMING PROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; BRAIN NERVE CELL; CONFERENCE PAPER; CONTROLLED STUDY; DRUG RECEPTOR BINDING; GENE EXPRESSION; GENE MUTATION; NONHUMAN; PROTEIN ANALYSIS; PROTEIN PHOSPHORYLATION; PROTEIN QUATERNARY STRUCTURE; RAT; SKELETAL MUSCLE;

ANIMALIA;

EID: 0027892935     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1993.tb38038.x     Document Type: Article

References (79)

1. Molecular properties of voltage‐sensitive sodium channels
2. Beta 2 subunits of sodium channels from vertebrate brain. Studies with subunit‐specific antibodies
3. β1 subunits of sodium channels. Studies with subunit‐specific antibodies
4. Primary structure of Electropborus electricus sodium channel deduced from cDNA sequence
5. Existence of distinct sodium channel messenger RNAs in rat brain
6. Primary structure of rat brain sodium channel III deduced from the cDNA sequence
7. Messenger RNA coding for only the α subunit of the rat brain Na channel is sufficient for expression of functional channels in Xenopus oocytes
8. + channel alpha subunit with novel gating properties
9. A neutral amino acid change in segment IIS4 dramatically alters the gating properties of the voltage‐dependent sodium channel
10. Primary structure and functional expression of the β1 subunit of the rat brain sodium channel
11. Expression of functional sodium channels from cloned cDNA
12. Functional expression of cloned cDNA encoding sodium channel III
13. Functional properties of rat brain sodium channels expressed in a somatic cell line
14. +‐channel inactivation
15. + channels, expressed in a mammalian cell line, by local anesthetic, antiarrhythmic, and anticonvulsant drugs
16. Molecular diversity of voltage‐dependent calcium channels
17. The biochemistry and molecular biology of the dihydropyridine‐sensitive calcium channel
18. Molecular properties of dihydropyridine‐sensitive calcium channels in skeletal muscle
19. Functional subunit composition of voltage‐gated calcium channels
20. Primary structure and functional expression of the cardiac dihydropyridine‐sensitive calcium channel
21. Induction of calcium currents by the expression of the alpha 1‐subunit of the dihydropyridine receptor from skeletal muscle
22. Primary structure of the receptor for calcium channel blockers from skeletal muscle
23. Subunits of purified calcium channels: a 212‐kDa form of α 1 and partial amino acid sequence of a phosphorylation site of an independent β subunit
24. Characterization of the two size forms of the α1 subunit of skeletal muscle L‐type calcium channels
25. Subunit structure and localization of dihydropyridine‐sensitive calcium channels in mammalian brain, spinal cord, and retina
26. 2+ channels at the base of major dendrites in hippocampal pyramidal neurons
27. Rat brain expresses a heterogeneous family of calcium channels
28. Molecular cloning of the α‐1 subunit of an ω‐conotoxin‐sensitive calcium channel
29. 2, and β subunits of a novel human neuronal calcium channel subtype
30. Classes of calcium channels in vertebrate cells
31. Calcium channels in vertebrate cells
32. 2+ channels in evoked release of norepinephrine from sympathetic neurons
33. Characterization of a calcium current in a vertebrate cholinergic presynaptic nerve terminal
34. Strategic location of calcium channels at transmitter release sites of frog neuromuscular synapses
35. G protein coupled mechanisms and nervous signaling
36. Purified ω‐conotoxin GVIA receptor of rat brain resembles a dihydropyridine‐sensitive L‐type calcium channel
37. Phosphorylation of an α‐like subunit of an ω‐conotoxin‐sensitive brain calcium channel by cAMP‐dependent protein kinase and protein kinase C
38. A monoclonal antibody to the β subunit of the skeletal muscle dihydropyridine receptor immunoprecipitates the brain ω‐conotoxin GVIA receptor
39. Biochemical properties and subcellular localization of an N‐type calcium channel α 1 subunit
40. Structure and functional expression of an ω‐conotoxin‐sensitive human N‐type calcium channel
41. Sodium channels and gating currents
42. The structure of the voltage‐sensitive sodium channel: inferences derived from computer aided analysis of the Electropborus electricus channel primary structure
43. Molecular model of the action potential sodium channel
44. Pursuing the structure and function of voltage‐gated channels
45. Structural parts involved in activation and inactivation of the sodium channel
46. + channel functions
47. Chemicals as tools in the study of excitable membranes
48. The receptor for tetrodotoxin and saxitoxin: a structural hypothesis
49. The binding of saxitoxin and tetrodotoxin to excitable tissue
50. A single point mutation confers tetrodotoxin and saxitoxin insensitivity on the sodium channel II
51. Mapping the site of block by tetrodotoxin and saxitoxin of sodium channel II
52. A point mutation of TTX‐resistant cardiac Na channels confers three properties of TTX‐sensitive Na channels
53. 2+ channels
54. Annus mirabilis for potassium channels
55. 5 region
56. + channels determined by an interacting pair of nonpolar amino acids
57. Calcium channel characteristics conferred on the sodium channel by single mutations
58. ++
59. Mechanism of ion permeation through calcium channels
60. Identification of an intracellular peptide segment involved in sodium channel inactivation
61. Inhibition of inactivation of single sodium channels by a site‐directed antibody
62. A voltage‐dependent gating transition induces usedependent block by tetrodotoxin of rat IIA sodium channels expressed in Xenopus oocytes
63. A phosphorylation site in a conserved intracellular loop that is required for modulation of sodium channels by protein kinase C
64. +‐channel inactivation: Charge neutralizations and deletions in the III—IV linker
65. Anatomy of a conformational change: hinged lid motion of the triosephosphate isomerase loop
66. A pro to gly mutation in the hinge of the arabinose‐binding protein enhances binding and alters specificity
67. Selective phosphorylation of the alpha subunit of the sodium channel by cAMP‐dependent protein kinase
68. Cyclic AMP‐dependent phosphorylation of the alpha subunit of the sodium channel in synaptic nerve ending particles
69. Cyclic AMP‐dependent phosphorylation of voltage‐sensitive sodium channels in primary cultures of rat brain neurons
70. Functional modulation of brain sodium channels by cAMP‐dependent phosphorylation
71. Identification of an intracellular domain of a sodium channel having multiple cyclic AMP‐dependent phosphorylation sites
72. Phosphorylation of the alpha subunit of rat brain sodium channels by cAMP‐dependent protein kinase at a new site containing Ser686 and Ser687
73. Phosphorylation of the alpha subunit of the sodium channel by protein kinase C
74. + channel reconstituted into phospholipid vesicles by protein kinase C
75. 2+ currents in mouse neuroblastoma cells
76. 2+, and γ‐aminobutyrate type A channels
77. + channel
78. Functional modulation of brain sodium channels by protein kinase C phosphorylation