The effect of the chemotherapeutic drug vp-16 on poly(adp-ribosylation) in apoptotic hela cells

Carcinogenesis

Volumn 14, Issue 12, 1993, Pages 2559-2564

  Negri, C ^a   Bernardi, R ^a   Braghetti, A ^a   Ricotti, G C B Astaldi ^a   Scovassi, A I ^a  

^a CNR   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOHEXIMIDE; DNA FRAGMENT; ETOPOSIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE;

ADENOSINE DIPHOSPHATE RIBOSYLATION; AGAR GEL ELECTROPHORESIS; APOPTOSIS; ARTICLE; CHROMATIN; CONTROLLED STUDY; DNA CLEAVAGE; HELA CELL; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; PRIORITY JOURNAL;

APOPTOSIS; CELL SURVIVAL; CHROMATOGRAPHY, AFFINITY; DNA; DNA, NEOPLASM; ELECTROPHORESIS, AGAR GEL; ETOPOSIDE; HELA CELLS; HUMAN; POLY ADENOSINE DIPHOSPHATE RIBOSE; SUPPORT, NON-U.S. GOV'T;

EID: 0027769836     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/14.12.2559     Document Type: Article

References (28)

1. Liu, L.F. (1989) DNA topoisomerase poisons as antitumor drugs. Anna. Rev. Biochan., 58, 351-375.
2. Minocha, A. and Long, B.H. (1984) Inhibition of the DNA catenation activity of type II topoisomerase by VP16-213 and VM26. Biochan. Biophys. Res. Common., 122, 165-170.
3. Kaufmarui, S.H. (1991) DNA topoisomerases in chemotherapy. Cancer Cells, 3, 24-27.
4. Zhang, H., D’Arpa, P. and Liu, L.F. (1990) A model for tumor cell killing by topoisomerase poisons. Cancer Cells, 2, 23-27.
5. Roy, C., Brown, D.L., Little, L. Valentine, B.K., Walker, P.R., Sikorska, M. and Chaly, N. (1992) The topoisomerase n inhibitor teniposide (VM-26) induces apoptosis in unstimulated mature murine lymphocytes. Exp. CelL Res., 200, 416-424.
6. Walker, P.R., Smith, C., Yoodale, T., Leblanc, L., Whitefield JF. and Sikorska, M. (1991) Topoisomerase D-reactive chemotherapeutic drugs induce apoptosis in thymocytes. Cancer Res., 51, 1078-1085.
7. Tepper, C.G. and Studzinsld, G.P. (1992) Teniposide induces mjclear but not mitochondrial DNA degradation. Cancer Res., 52, 3384-3390.
8. WiUiams, G.T., Smith, C.A., McCarthy, N.J. and Grimes, L.A. (1992) Apoptosis: final control point in cell biology. Trends Cell Biol., 2, 263-267.
9. Kaufinann, S. (1989) Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic antkancer drugs: a cautionary note. Cancer Res., 49, 5870-5878.
10. Katifmann, S.H. (1991) Antagonism between camptothecin and topoisomerase n-directed chemotherapeutic agents in a human leukemia cell line. Cancer Res., 51, 1129-1136.
11. Shimizu, T., Kubota, M., Tanizawa, A., Sano, H., Kasai, Y., Hashimoto, H., Akiyama, Y. and Mikawa, H. (1990) Inhibition of both etoposide-induced fragmentation and activation of poly(ADP-ribose)synthesis by zinc ion. Biochem. Biophys. Res. Common., 169, 1172-1177.
12. Tanizawa A., Kubota, M., Hashimoto, H., Shimizu, T., Taldmoto, T., Kitoh, T., Akiyama, Y. and Mikawa, H. (1989) VP-16-induced nucleotide pool changes and poly(ADP-ribose) synthesis: the role of VP-16 in interphase death. Exp. Cell Res., 185, 237-246.
13. Tanizawa, A., Kubota, M., Taldmoto, T., Akiyma, Y., Seto, S., Kiriyama, Y. and Mikawa, H. (1987) Prevention of adriamycin-induced interphase death by 3-aminobenzamide and nicotinamide in a human promyelocytic leukemia cell line. Biochem. Biophys. Res. Common., 144, 1031-1036.
14. Shall, S. (1984) ADP-ribose in DNA repair a new component of DNA excision repair. Adv. Radial. BioL, 11, 1-69.
15. Carson, D.A., Seto, S., Wasson, B. and Carrera, J. (1986) DNA strand breaks, NAD metabolism, and programmed cell death. Exp. Cell Res., 164, 273-281.
16. Negri, C., Chiesa, R., Cerino, A., Bestagno, M., Sala, C., Zini, N., Maraldi, N.M. and Astaldi Ricotti, G.C.B. (1992) Monoclonal antibodies to human DNA topoisomerase I and the two isoforms of DNA topoisomerase II: 170-and 180-kDa isozymes. Exp. Cell Res., 200, 452-459.
17. Negri, C., Scovassi AI., Braghetti, A., Guano, F. and Astaldi Ricotti, G.C.B. (1993) DNA topoisomerase n 0: stability and distribution in different animal cells in comparison to DNA topoisomerase I and II a. Exp. Cell Res., 206, 128-133.
18. Simonin, F., Mfnissier-de Murcia, L., Poch, O., Muller, S., Gradwohl, G., Molinete, M., Penning, C., Keith, G. and de Murcia, G. (1990) Expression and site directed mutagenesis of the catalytic domain of human poly(ADP-ribose)polymerase in E.coli\ lysine-893 is critical to activity. J. BioL Chem., 265, 19249-19256.
19. Scovassi VL, Steferrini, M., Lagomarsini J., Izzo, R. and Bertazzoni, U. (1987) Response of mammalian ADP-ribosyl transferase to lymphocyte stimulation, mutagen treatment and cell cycling. Carcinogenesis, 9, 1295-1300.
20. Bradford, M.M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem., 72, 248-254.
21. Surowy, C.S. and Berger, N.A. (1983) Unique acceptors for po)y(ADP-ribose) in resting, proliferating and DNA-damaged human lymphocytes. Biochim. Biophys. Ada, 740, 8-18.
22. Adamietz, P. and Hilz, H. (1984) Purification and characterization of (ADP-ribosyl)n proteins. Methods Enzymol., 106, 461-471.
23. Scovassi, A.I., Mariani, C., Negroni, M., Negri, C. and Bertazzoni, U. (1993) ADP-ribosylation of non-histone proteins in HeLa cells: modification of DNA topoisomerase n. Exp. Cell Res., 206, 177-181.
24. Towbin, H., Staehelin, T. and Gordon, J. (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. NatL Acad. Sd. USA, 76, 4350-4354.
25. Scovassi, A.I., Stefanini, M. and Bertazzoni, U. (1984) Catalytic activities of human poly(ADP-ribose)polyroerase from normal and mutagenized cells detected after sodium dodecyl sulfate-polyacrylamide gel electrophoresis. J. BioL Chem., 259, 10973-10977.
26. Hotz, M.A., Traganos, F. and Darzynlriewicz, Z. (1992) Changes in nuclear chromatin related to apoptosis or necrosis by the DNA topoisomerase II inhibitor fostriecin in MOLT-4 and HL-60 cells are revealed by altered DNA sensitivity to denaturation. Exp. Cell Res., 201, 184-191.
27. Betger, N.A. (1985) Poly(ADP-ribose) in the cellular response to DNA damage. Radial. Res., 101, 4-15.
28. Wintersberger, U. and Wintersberger, E. (1985) Poly(ADP-ribosyl)ation. Cellular emergency reactions? FEBS Lett., 188, 189-191.