Quantification of myocardium at risk and detection of reperfusion by dynamic vectorcardiographic ST segment monitoring in a pig occlusion-reperfusion model

Cardiovascular Research

Volumn 27, Issue 12, 1993, Pages 2170-2178

  Näslund, Ulf ^a,b   Häggmark, Sören ^a,b   Johansson, Göran ^a,b   Reiz, Sebastian ^a,b  

^a UMEÅ UNIVERSITY HOSPITAL   (Sweden)

^b Department of Anaesthesiology ^*  (Canada)

Author keywords

Computerised; Myocardial ischaemia; Myocardium at risk; Pig; Reperfusion; ST segment; ST vector; Vectorcardiography

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY OBSTRUCTION; HEART INFARCTION; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEMODYNAMICS; NONHUMAN; PRIORITY JOURNAL; RISK ASSESSMENT; ST SEGMENT DEPRESSION; SWINE; VECTORCARDIOGRAPHY;

ANIMAL; AUTOMATIC DATA PROCESSING; AUTORADIOGRAPHY; DISEASE MODELS, ANIMAL; HEART; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; ORGAN WEIGHT; RISK; SUPPORT, NON-U.S. GOV'T; SWINE; VECTORCARDIOGRAPHY;

EID: 0027769716     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1093/cvr/27.12.2170     Document Type: Article

References (37)

1. Schaper W, Remijsen P, Xhonneux R. The size of myocardial infarction after experimental coronary artery ligation. Z Kreislaufforsch 1969;58:904-9.
2. Lowe JE, Reimer KA, Jennings RB. Experimental infarct size as a function of the amount of myocardium at risk. Am J Pathol 1978;90:363-79.
3. Lee JT, Ideker RE, Reimer KA. Myocardial infarct size and location in relation to the coronary vascular bed at risk in man. Circulation 1981;64:526-34.
4. von Essen R, Schmidt W, Uebis R, et al. Myocardial infarction and thrombolysis. Electrocardiographic short term and long term results using precordial mapping. Br Heart J 1985;54:6-10.
5. Krucoff MW, Green CE, Satler LF, et al. Noninvasive detection of coronary artery patency using continuous ST-segment monitoring. Am J Cardiol 1986;57:916-22.
6. Kircher BJ, Topol EJ, O’Neill WW, Pitt B. Prediction of infarct coronary artery recanalization after intravenous thrombolytic therapy. Am J Cardiol 1987;59:513-5.
7. Hogg KJ, Hornung RS, Howie CA, Hockings N, Dunn FG, Hillis WS. Electrocardiographic prediction of coronary artery patency after thrombolytic treatment in acute myocardial infarction; use of the ST segment as a non-invasive marker. Br Heart J 1988;60:275-80.
8. Califf RM, O’Neill W, Stack RS, et al. Failure of simple clinical measurement to predict perfusion status after intravenous thrombolysis. Ann Intern Med 1988;108:658-62.
9. Richardson SG, Morton P, Murtagh JG, Scott ME, O’Keefe DB. Relation of coronary arterial patency and left ventricular function to electrocardiographic changes after streptokinase treatment during acute myocardial infarction. Am J Cardiol 1988; 61:961-5.
10. Saran RK, Been M, Furniss SS, Hawkins T, Reid DS. Reduction in ST segment elevation after thrombolysis predicts either coronary reperfusion or preservation of left ventricular function. Br Heart J 1990;64:113-7.
11. Blanke H, von Hardenberg D, Cohen M, et al. Patterns of creatine kinase release during acute myocardial infarction after nonsurgical reperfusion: comparison with conventional treatment and correlation with infarct size. J Am Coli Cardiol 1984;3:675-80.
12. Zabel M, Hohnloser SH, Parussel A, Just H. ST segment analysis for assessment of coronary artery patency; comparison of surface ECG and Holter recordings. Eur Heart J 1992;13:1619-25.
13. Frank E. Accurate, clinically practical system for spatial vectorcardiography. Circulation 1956;13:737-44.
14. Näslund U, Häggmark S, Johansson G, Marklund SL, Reiz S. A closed-chest myocardial occlusion-reperfusion model in the pig: techniques, morbidity and mortality. Eur Heart J 1992; 13:1282-9.
15. Näslund U, Häggmark S, Johansson G, Reiz S. Ischemia and reperfusion induced transient QRS vector changes: relationship to size of the ischaemic territory. Cardiovasc Res 1993:27:327-33.
16. DeBoer LWV, Strauss HW, Kloner RA, et al. Autoradiographic method for measuring the ischemic myocardium at risk: effects of verapamil on infarct size after experimental coronary artery occlusion. Proc Natl Acad Sci USA 1980:77:6119-23.
17. Downey JM, Chambers D, Wilkerson RD. The inability of isoproterenol or propranolol to alter the lateral dimensions of experimentally induced myocardial infarcts. Basic Res Cardiol 1982;77:486-98.
18. Boor PJ, Reynolds ES. A simple planimetrie method for determination of left ventricular mass and necrotic myocardial mass in postmortem hearts. Am J Clin Pathol 1977;68:387-92.
19. Sederholm M, Erhardt L, Sjögren A. Continuous vectorcardiography in acute myocardial infarction. Natural course of ST and QRS vectors. Int J Cardiol 1983;4:53-63.
20. Wohl H. The CuSum plot: its utility in the analysis of clinical data. N Engl J Med 1977;296:1044-5.
21. Gröttum P, Mohr P, Kjekshus JK. Evolution of vectorcardiographic QRS changes during myocardial infarction in dogs and their relation to infarct size. Cardiovasc Res 1986;20:108-16.
22. Dellborg M, Riha M, Swedberg K. Dynamic QRS- and ST-segment changes in myocardial infarction monitored by continuous on-line vectorcardiography. J Electrocardiol 1991; 23(suppl): 11-19.
23. Dellborg M, Emanuelsson H, Riha M, Swedberg K. Dynamic QRS-complex and ST-segment monitoring by continuous vectorcardiography during coronary angioplasty. Coronary Artery Dis 1991;2:43-53.
24. White FC, Bloor CM. Coronary collateral circulation in the pig: correlation of collateral flow with coronary bed size. Basic Res Cardiol 1981;76:189-96.
25. Maroko PR, Kjekshus JK, Sobel BE, et al. Factors influencing infarct size following experimental coronary artery occlusions. Circulation 1971:43:67-82.
26. Maroko PR. Libby P. Covell JW. Sobel BE, Ross J, Braunwald E. Precordial ST-segment elevation mapping: an atraumatic method for assessing alterations in the extent of myocardial ischemic injury. Am J Cardiol 1972:29:223-39.
27. Muller JE, Maroko PR, Braunwald E. Evaluation of precordial electrocardiographic mapping as a means of assessing changes in myocardial ischemic injury. Circulation 1975:52:16-27.
28. Capone RJ, Most AS, Sydlik PA. Precordial ST segment mapping. A sensitive technique for the evaluation of myocardial injurv? Chest 1975:67:577-82.
29. Askenazi J, Maroko PR, Lesen M, Braunwald E. Usefulness of ST segment elevations as predictors of electrocardiographic signs of necrosis in patients with acute myocardial infarction. Br Heart J 1977;39:764-70.
30. Sederholm M, Gröttum P, Erhardt L, Kjekshus J. Quantitative assessment of myocardial ischemia and necrosis by continuous vectorcardiography and measurement of creatine kinase release in patients. Circulation 1983:68:1006-12.
31. Aldrich HR, Wagner NB, Boswick J, et al. Use of initial ST-segment deviation for prediction of final electrocardiographic size of acute myocardial infarcts. Am J Cardiol 1988;61:749-53.
32. Mauri F, Gasparini M, Barbonaglia L, et al. Prognostic significance of the extent of myocardial injury in acute myocardial infarction treated by streptokinase (the GISSI trial). Am J Cardiol 1989;63:1291-5.
33. Chou TC. When is the vectorcardiogram superior to the scalar electrocardiogram? J Am Coll Cardiol 1986;8:791-9.
34. Bailey JJ, Berson AS, Garson A, et al. Recommendations for standardization and specifications in automated electrocardiography: bandwidth and digital signal processing. A report for health professionals by an ad hoc writing group of the Committee on Electrocardiography and Cardiac Electrophysiology of the Council on Clinical Cardiology, American Heart Association. Circulation 1990;81:730-9.
35. Dellborg M, Topol EJ, Swedberg K. Dynamic QRS-complex and ST-segment vectorcardiographic monitoring can identify vessel patency in patients with acute myocardial infarction treated with reperfusion therapy. Am Heart J 1991;122:943-8.
36. Dissman R, Goerke M, von Amelin H, Schröder J, Linderer T, Schröder R. Do transient ST-segment elevations immediately following reperfusion indicate reperfusion injury? (Abstract) Circulation 1990;82(suppl 3):279A.
37. Shechter M, Hod H, Modan M, Kaplinsky E, Rabonowitz B. New electrocardiographic sign during the first hour of thrombolysis: its significance in relation to ejection fraction. (Abstract) Eur Heart J 1990;11 (suppl 3):354A.