Arachidonic acid stimulates interleukin-6 release from rat peritoneal macrophages in vitro: Evidence for a prostacyclin-dependent mechanism

Prostaglandins, Leukotrienes and Essential Fatty Acids

Volumn 49, Issue 6, 1993, Pages 915-922

  Holladay, C S ^a   Wright, R M ^a   Spangelo, B L ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONIC ACID; INTERLEUKIN 6; PROSTACYCLIN; THROMBOXANE B2;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; RAT;

ANIMAL; ARACHIDONIC ACID; EPOPROSTENOL; ILOPROST; IN VITRO; INTERLEUKIN-6; KINETICS; MACROPHAGES, PERITONEAL; MALE; PROSTAGLANDINS, SYNTHETIC; PYRIDINES; RATS; SUPPORT, U.S. GOV'T, P.H.S.; THROMBOXANE A2; THROMBOXANE-A SYNTHASE;

ANIMALIA;

EID: 0027764488     PISSN: 09523278     EISSN: None     Source Type: Journal    
DOI: 10.1016/0952-3278(93)90176-W     Document Type: Article

References (25)

1. IL-6 receptor and mechanism of signal transduction
2. The biology of interleukin-6
3. Circulating cytokines: the tip of the iceberg?
4. Secretory products of macrophages
5. The expression of interleukin-6 by a rat macrophage derived cell line
6. Differential regulation of interleukin-6, macrophage inflammatory protein-1, and JE/MCP-1 cytokine expression in macrophage cell lines
7. Arachidonic acid stimulates interleukin-6 release from rat anterior pituitary cells in vitro: comparison with peritoneal macrophages
8. The complex pattern of cytokines in sepsis
9. Signal paths and regulation of superoxide, eicosanoid and cytokine formation in macrophages of rat liver
10. Kupffer Cells May Autoregulate Interleukin 1 Production by Producing Interleukin 1 Inhibitor and Prostaglandin E2
11. 4 enhances interleukin-6 (IL-6) production and IL-6 messenger RNA accumulation in human monocytes in vitro: transcriptional and posttranscriptional mechanisms
12. Altered responses to modulators of guanine nucleotide binding protein activity in endotoxin tolerance
13. Production of interleukin-6 by anterior pituitary cells is stimulated by increased intracellular adenosine 3′,5′-monophosphate and vasoactive intestinal peptide
14. Rapid colormetric assay for cell viability: application to the quantitation of cytotoxic and growth inhibitory lymphokines
15. CGS 12970: a novel: long acting thromboxane synthetase inhibitor
16. Pharmacokinetics of CGS 12970 and inhibition of thromboxane synthesis after oral administration in healthy adults
17. Synthesis of ciloprost (ZK 36 374): a chemically stable and biologically potent prostacyclin analog
18. Comparison of iloprost, cicaprost and prostacyclin effects on cyclic AMP metabolism in intact platelets
19. 2-receptors in human platelets
20. Effects of thromboxane synthetase inhibition on arachidonate metabolism and platelet behaviour.
21. Synthesis of interleukin-6 (interferon-β2/B cell stimulatory factor 2) in human fibroblasts is triggered by an increase in intracellular cyclic AMP
22. Involvement of prostaglandins and leukotrienes in the pathogenesis of endotoxemia and sepsis
23. Regulation of the acute phase response an neuroendocrine function by interleukin-6
24. 2 production in cultured bovine vascular endothelial cells