Debrisoquin and mephenytoin hydroxylation phenotypes and CYP2D6 genotype in patients treated with neuroleptic and antidepressant agents

Clinical Pharmacology & Therapeutics

Volumn 54, Issue 6, 1993, Pages 606-611

  LLerena, Adrián ^a,b,c   Herraíz, Angustias G ^a,b,c   Cobaleda, Jesús ^a,b,c   Johansson, Inger ^a,b,c   Dahl, Marja‐Liisa ^a,b,c  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c Psychiatric Hospital Adolfo Díaz Ambrona ^*  (Venezuela)

Author keywords

[No Author keywords available]

Indexed keywords

AMITRIPTYLINE; ANTIDEPRESSANT AGENT; CLOMIPRAMINE; CLOZAPINE; DEBRISOQUINE; HALOPERIDOL; IMIPRAMINE; LEVOMEPROMAZINE; MAPROTILINE; MEPHENYTOIN; MIANSERIN; NEUROLEPTIC AGENT; PIMOZIDE; PIPOTIAZINE; THIORIDAZINE; TRIFLUOPERAZINE;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DRUG HYDROXYLATION; DRUG METABOLISM; FEMALE; GENOTYPE; HUMAN; HUMAN EXPERIMENT; MAJOR CLINICAL STUDY; MALE; MENTAL PATIENT; NORMAL HUMAN; PHENOTYPE; PRIORITY JOURNAL; VOLUNTEER;

ADULT; AGED; ANTIDEPRESSIVE AGENTS; ANTIPSYCHOTIC AGENTS; CYTOCHROME P-450 CYP2D6; CYTOCHROME P-450 ENZYME SYSTEM; DEBRISOQUIN; FEMALE; GENOTYPE; HUMAN; HYDROXYLATION; MALE; MEPHENYTOIN; MIDDLE AGE; MIXED FUNCTION OXYGENASES; PHENOTYPE; POLYMORPHISM (GENETICS); SUPPORT, NON-U.S. GOV'T;

EID: 0027755278     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/clpt.1993.197     Document Type: Article

References (0)