Chromatin structure and the expression of globin-encoding genes

Gene

Volumn 135, Issue 1-2, 1993, Pages 119-124

  Felsenfeld, Gary ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

chromatin domain; GATA 1; locus control region; nucleosome; supercoiling; trans acting factors; Transcription

Indexed keywords

GLOBIN;

CHICKEN; CHROMATIN STRUCTURE; CONFERENCE PAPER; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GLOBIN GENE; NONHUMAN; NUCLEOSOME; PRIORITY JOURNAL;

ANIMAL; CHICK EMBRYO; CHROMATIN; DNA, SUPERHELICAL; GENE EXPRESSION REGULATION; GLOBINS;

EUKARYOTA; GALLUS GALLUS;

EID: 0027731735     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-1119(93)90056-9     Document Type: Article

References (41)

1. Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein
2. The transcriptionally active MMTV promoter is depleted of histone H1
3. The erythroid cell haemoglobins of the chicken embryo
4. A 3' enhancer is required for temporal and tissue-specific transcriptional activation of the chicken adult β-globin gene
5. Developmental regulation of β-globin gene switching
6. A 5' element of the chicken β-globin domain serves as an insulator in human erythroid cells and protects against position-effect in Drosophila
7. Formation of nucleosomes on positively supercoiled DNA
8. A nucleosome core is transferred out of the path of a transcribing polymerase
9. Specific factor conferring nuclease hypersensitivity at the 5' end of the chicken adult beta globin gene
10. Interaction of specific nuclear factors with the nuclease-hypersensitive region of the chicken adult globin gene: nature of the binding domain
11. The erythroid-specific transcription factor Eryf 1: a new finger protein
12. An erythrocyte-specific DNA binding factor recognizes a regulatory sequence common to all chicken globin genes
13. Chromatin as an essential part of the transcriptional mechanism
14. Position-independent high level expression of the human β-globin gene in transgenic mice
15. Activation of globin genes during chicken development
16. Structure and promoter activity of the gene for the erythroid transcription factor GATA-1
17. Regulated gene expression in transfected primary chicken erythrocytes
18. Erythroid transcription factor GATA-1 is abundantly transcribed in mouse testis
19. β-globin gene inactivation by DNA translocation in γ,β thalassemia
20. Identification and characterization of a chicken α-globin enhancer
21. π, the chicken embryonic α-globin gene
22. Role of nucleosomal cores and histone H1 in regulation of transcription by RNA polymerase II
23. Supercoiling of the DNA template during transcription
24. Expression of an erythroid transcription factor in megakaryocytic and mast cell lineages
25. A 200 base pair region at the 5' end of the chicken adult β-globin gene is accessible to nuclease digestion
26. The developmental switch in embryonic ρ-globin expression is correlated with erythroid lineagespecific differences in transcription factor levels
27. Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1
28. Mutational analysis of the chicken β-globin enhancer reveals two positive-acting domains
29. Developmental regulation of topoisomerase II sites and Dnase I hypersensitive sites in the chicken β-globin locus
30. a-globin gene in transgenic mice
31. An enhancer/ locus control region is not sufficient to open chromatin
32. A dominant control region from the human β-globin locus conferring integration site-independent gene expression
33. The sequence, modular structure and evolution of a human erythroid transcription factor
34. Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells
35. Transcription-driven supercoiling of DNA: direct biochemical evidence from in vitro studies
36. The β-like-globin gene domain in human erythroid cells
37. The human β-globin gene 3' enhancer contains multiple binding sites for an crythroid-specific protein
38. Chromosomal subunits in active genes have an altered conformation
39. Nucleosome core displacement in vitro via a metastable transcription factor-nucleosome complex
40. The chromatin structure of specific genes I. Evidence for higher order domains of denned DNA sequence
41. The major human erythroid DNA-binding protein (GF-1): primary sequence and localization of the gene to the X chromosome