메뉴 건너뛰기




Volumn 5, Issue 6, 1993, Pages 431-441

Neurotrophic factors and neural grafts: A growing field

Author keywords

Intracerebral grafts; Neurotrophic factors

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; FIBROBLAST GROWTH FACTOR; NERVE GROWTH FACTOR; NEUROTROPIC AGENT;

EID: 0027730561     PISSN: 10445765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1044-5765(05)80015-6     Document Type: Article
Times cited : (10)

References (114)
  • 1
    • 0038565781 scopus 로고
    • Pathology of Parkinson’s disease; the importance of the substantia nigra and Lewy bodies
    • Stern G, Chapman and Hall, London
    • Forno LS (1990) Pathology of Parkinson’s disease; the importance of the substantia nigra and Lewy bodies, in Parkinson’s disease (Stern G, ed), pp 185-238. Chapman and Hall, London
    • (1990) Parkinson’s Disease , pp. 185-238
    • Forno, L.S.1
  • 2
    • 0022876328 scopus 로고
    • Huntington’s disease. Pathogenesis and management
    • Martin JB, Gusella JF (1986) Huntington’s disease. Pathogenesis and management. New Engl J Med 315:1267-1276
    • (1986) New Engl J Med , vol.315 , pp. 1267-1276
    • Martin, J.B.1    Gusella, J.F.2
  • 3
    • 0024369761 scopus 로고
    • The neuroanatomy of Alzheimer’s disease
    • Pearson RCA, Powell TPS (1989) The neuroanatomy of Alzheimer’s disease. Rev Neurosci 2:101-121
    • (1989) Rev Neurosci , vol.2 , pp. 101-121
    • Pearson, R.1    Powell, T.2
  • 4
    • 0023869802 scopus 로고
    • Amyotrophic lateral sclerosis. Recent advances in pathogenesis and therapeutic trials
    • Mitsumoto H, Hanson MR, Chad DA (1988) Amyotrophic lateral sclerosis. Recent advances in pathogenesis and therapeutic trials. Arch Neurol 45:189-202
    • (1988) Arch Neurol , vol.45 , pp. 189-202
    • Mitsumoto, H.1    Hanson, M.R.2    Chad, D.A.3
  • 5
    • 0027480960 scopus 로고
    • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington’s disease chromosomes
    • Huntington’s Disease Collaborative Research Group (1993) A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington’s disease chromosomes. Cell 72:971-983
    • (1993) Cell , vol.72 , pp. 971-983
  • 6
    • 0026603230 scopus 로고
    • Anatomy and connectivity of intrastriatal striatal transplants
    • Wictorin K (1992) Anatomy and connectivity of intrastriatal striatal transplants. Prog Neurobiol 38:611-639
    • (1992) Prog Neurobiol , vol.38 , pp. 611-639
    • Wictorin, K.1
  • 7
    • 0027487866 scopus 로고
    • Huntington’s disease: Animal models and transplantation repair
    • Dunnett SB, Svendsen CN (1993) Huntington’s disease: Animal models and transplantation repair. Curr Opin Neuriobiol, in press
    • (1993) Curr Opin Neuriobiol
    • Dunnett, S.B.1    Svendsen, C.N.2
  • 8
    • 0026939784 scopus 로고
    • Dopaminergic transplants in experimental parkinsonism: Cellular mechanisms of graft induced functional recovery
    • Björklund A (1992) Dopaminergic transplants in experimental parkinsonism: Cellular mechanisms of graft induced functional recovery Curr Opin Neurobiol 2:683-689
    • (1992) Curr Opin Neurobiol , vol.2 , pp. 683-689
    • Björklund, A.1
  • 9
    • 0023688111 scopus 로고
    • What, if anything, is a neurotrophic factor?
    • Barde Y-A (1988) What, if anything, is a neurotrophic factor? Trends Neurosci 11:343-346
    • (1988) Trends Neurosci , vol.11 , pp. 343-346
    • Barde, Y.-A.1
  • 10
    • 0025877704 scopus 로고
    • The changing scene of neurotrophic factors
    • Thoenen H (1991) The changing scene of neurotrophic factors. Trends Neurosci 14:165-170
    • (1991) Trends Neurosci , vol.14 , pp. 165-170
    • Thoenen, H.1
  • 11
    • 0019781601 scopus 로고
    • A unifying hypothesis for the cause of amyotrophic lateral sclerosis, parkinsonism and Alzheimer’s disease
    • Appel SH (1981) A unifying hypothesis for the cause of amyotrophic lateral sclerosis, parkinsonism and Alzheimer’s disease. Ann Neurol 10:499-505
    • (1981) Ann Neurol , vol.10 , pp. 499-505
    • Appel, S.H.1
  • 12
    • 0025727691 scopus 로고
    • Parkinson’s disease management
    • Clough CG (1991) Parkinson’s disease management. Lancet 337:1324-1327
    • (1991) Lancet , vol.337 , pp. 1324-1327
    • Clough, C.G.1
  • 13
    • 0027319917 scopus 로고
    • The biology and behaviour of intracerebral adrenal transplants in animals and man
    • Barker RA, Dunnett SB (1993) The biology and behaviour of intracerebral adrenal transplants in animals and man Rev Neurosci 4:113-146
    • (1993) Rev Neurosci , vol.4 , pp. 113-146
    • Barker, R.A.1    Dunnett, S.B.2
  • 14
    • 0025912187 scopus 로고
    • Substantia nigra grafts and Parkinson’s disease: From animal experiments to human therapeutic trials
    • Freed WJ (1991) Substantia nigra grafts and Parkinson’s disease: From animal experiments to human therapeutic trials. Restor Neurol Neurosci 3:109-134
    • (1991) Restor Neurol Neurosci , vol.3 , pp. 109-134
    • Freed, W.J.1
  • 15
    • 0022243842 scopus 로고
    • Immunohistochemical and biochemical study on the noradrenaline and adrenaline storing cells of the adrenal medulla of the rat
    • Verhofstad AAJ, Coupland RE, Parker TR, Goldstein M (1985) Immunohistochemical and biochemical study on the noradrenaline and adrenaline storing cells of the adrenal medulla of the rat. Cell Tiss Res 242:233-243
    • (1985) Cell Tiss Res , vol.242 , pp. 233-243
    • Verhofstad, A.1    Coupland, R.E.2    Parker, T.R.3    Goldstein, M.4
  • 16
    • 0019828712 scopus 로고
    • High performance liquid chromatography with electrochemical detection as a highly efficient tool for studying catecholaminergic systems I. Quantification of noradrenaline, adrenaline and dopamine in cultured adrenal medullary cells
    • Müller TH, Unsicker K (1981) High performance liquid chromatography with electrochemical detection as a highly efficient tool for studying catecholaminergic systems I. Quantification of noradrenaline, adrenaline and dopamine in cultured adrenal medullary cells. J Neurosci Methods 4:39-52
    • (1981) J Neurosci Methods , vol.4 , pp. 39-52
    • Müller, T.H.1    Unsicker, K.2
  • 18
    • 84911258511 scopus 로고
    • Adrenal medulla grafts in hemiparkinsonian rats: Mechanisms mediating recovery of function
    • Becker JB, Curran EJ (1992) Adrenal medulla grafts in hemiparkinsonian rats: Mechanisms mediating recovery of function Restor Neurol Neurosci 4:174
    • (1992) Restor Neurol Neurosci , vol.4 , pp. 174
    • Becker, J.B.1    Curran, E.J.2
  • 19
    • 0023152420 scopus 로고
    • Open microsurgical autograft of adrenal medulla to the right caudate nucleus in two patients with intractable Parkinson’s disease
    • Madrazo I, Drucker-Colin R, Diaz V, Martinez-Mata J, Torres C, Beccerrill JJ (1987) Open microsurgical autograft of adrenal medulla to the right caudate nucleus in two patients with intractable Parkinson’s disease. N Engl J Med 316:831-834
    • (1987) N Engl J Med , vol.316 , pp. 831-834
    • Madrazo, I.1    Drucker-Colin, R.2    Diaz, V.3    Martinez-Mata, J.4    Torres, C.5    Beccerrill, J.J.6
  • 20
    • 0025935786 scopus 로고
    • United Parkinson Foundation Neurotransplantation registry on adrenal medullary transplants: Presurgical and 1 and 2 year follow up
    • Goetz CG, Stebbins GT, Klawans HL, Koller WC, Grossman MD, Bakay RAE, Penn RD, United Parkinson Foundation Neural Transplantation Registry (1992) United Parkinson Foundation Neurotransplantation registry on adrenal medullary transplants: Presurgical and 1 and 2 year follow up. Neurology 41:1719-1722
    • (1992) Neurology , vol.41 , pp. 1719-1722
    • Goetz, C.G.1    Stebbins, G.T.2    Klawans, H.L.3    Koller, W.C.4    Grossman, M.D.5    Bakay, R.6    Penn, R.D.7
  • 21
    • 0027411599 scopus 로고
    • The role of positron emission tomography in the assessment of human neurotransplantation
    • Sawle GV, Myers R (1993) The role of positron emission tomography in the assessment of human neurotransplantation. Trends Neurosci 16:172-176
    • (1993) Trends Neurosci , vol.16 , pp. 172-176
    • Sawle, G.V.1    Myers, R.2
  • 22
    • 0019124289 scopus 로고
    • Restoration of dopaminergic function by grafting of fetal rat substantia nigra to the caudate nucleus: Long term behavioral, biochemical and histochemical studies
    • Freed WJ, Perlow MJ, Karoum F, Seiger A, Olson L, Hoffer BJ, Wyatt RJ (1980) Restoration of dopaminergic function by grafting of fetal rat substantia nigra to the caudate nucleus: Long term behavioral, biochemical and histochemical studies. Ann Neurol 8:510-519
    • (1980) Ann Neurol , vol.8 , pp. 510-519
    • Freed, W.J.1    Perlow, M.J.2    Karoum, F.3    Seiger, A.4    Olson, L.5    Hoffer, B.J.6    Wyatt, R.J.7
  • 23
    • 0023281057 scopus 로고
    • Synaptic input and local output of dopaminergic neurons in grafts that functionally reinnervate the host neostriatum
    • Bolam JP, Freund TF, Björklund A, Dunnett SB, Smith AD (1987) Synaptic input and local output of dopaminergic neurons in grafts that functionally reinnervate the host neostriatum. Exp Brain Res 68:131-146
    • (1987) Exp Brain Res , vol.68 , pp. 131-146
    • Bolam, J.P.1    Freund, T.F.2    Björklund, A.3    Dunnett, S.B.4    Smith, A.D.5
  • 24
    • 0021916279 scopus 로고
    • Efferent synaptic connections of grafted dopaminergic neurons reinnervating the host neostriatum: A tyrosine hydroxylase immunocytochemical study
    • Freund TF, Bolam JP, Björklund A, Stenevi U, Dunnett SB, Powell JF, Smith AD (1985) Efferent synaptic connections of grafted dopaminergic neurons reinnervating the host neostriatum: A tyrosine hydroxylase immunocytochemical study. J Neurosci 5:603-616
    • (1985) J Neurosci , vol.5 , pp. 603-616
    • Freund, T.F.1    Bolam, J.P.2    Björklund, A.3    Stenevi, U.4    Dunnett, S.B.5    Powell, J.F.6    Smith, A.D.7
  • 25
    • 0019855516 scopus 로고
    • Grafts of embryonic substantia nigra reinnervating the ventrolateral striatum ameliorate sensorimotor impairments and akinesia in rats with 6-OHDA lesions of the nigrostriatal pathway
    • Dunnett SB, Björklund A, Stenevi U, Iversen SD (1981) Grafts of embryonic substantia nigra reinnervating the ventrolateral striatum ameliorate sensorimotor impairments and akinesia in rats with 6-OHDA lesions of the nigrostriatal pathway. Brain Res 229:209-217
    • (1981) Brain Res , vol.229 , pp. 209-217
    • Dunnett, S.B.1    Björklund, A.2    Stenevi, U.3    Iversen, S.D.4
  • 27
    • 0026448258 scopus 로고
    • Fetal tissue transplants in Parkinson’s disease
    • Fahn S (1992) Fetal tissue transplants in Parkinson’s disease. N Engl J Med 327:1589-1590
    • (1992) N Engl J Med , vol.327 , pp. 1589-1590
    • Fahn, S.1
  • 28
    • 0021821916 scopus 로고
    • Environmental influences in the development of neural crest derivatives: Glucocorticoids, growth factors and chromaffin cell plasticity
    • Doupe AJ, Landis SC, Patterson PH (1985) Environmental influences in the development of neural crest derivatives: Glucocorticoids, growth factors and chromaffin cell plasticity. J Neurosci 5:2119-2142
    • (1985) J Neurosci , vol.5 , pp. 2119-2142
    • Doupe, A.J.1    Landis, S.C.2    Patterson, P.H.3
  • 29
    • 0022258341 scopus 로고
    • Small intensely fluorescent cell in culture: Role of glucocorticoids and growth factors in their development and interconversions with other neural crest derivatives
    • Doupe AJ, Patterson PH, Landis SC (1985) Small intensely fluorescent cell in culture: Role of glucocorticoids and growth factors in their development and interconversions with other neural crest derivatives. J Neurosci 5:2143-2160
    • (1985) J Neurosci , vol.5 , pp. 2143-2160
    • Doupe, A.J.1    Patterson, P.H.2    Landis, S.C.3
  • 30
    • 0021874786 scopus 로고
    • Nerve fibre production by intraocular adrenal medullary grafts: Stimulation by nerve growth factor or by sympathetic denervation of the host iris
    • Stromberg I, Ebendal T, Seiger A, Olson L (1985) Nerve fibre production by intraocular adrenal medullary grafts: Stimulation by nerve growth factor or by sympathetic denervation of the host iris. Cell Tiss Res 241:241-249
    • (1985) Cell Tiss Res , vol.241 , pp. 241-249
    • Stromberg, I.1    Ebendal, T.2    Seiger, A.3    Olson, L.4
  • 31
    • 0022380380 scopus 로고
    • Chronic implants of chromaffin tissue into the dopamine denervated striatum. Effects of NGF on graft survival, fiber outgrowth and rotational behavior
    • Stromberg I, Herrera-Marschitz M, Ungerstedt U, Ebendal T, Olson L (1985) Chronic implants of chromaffin tissue into the dopamine denervated striatum. Effects of NGF on graft survival, fiber outgrowth and rotational behavior. Exp Brain Res 60:335-349
    • (1985) Exp Brain Res , vol.60 , pp. 335-349
    • Stromberg, I.1    Herrera-Marschitz, M.2    Ungerstedt, U.3    Ebendal, T.4    Olson, L.5
  • 32
    • 0025947311 scopus 로고
    • The use of genetically altered astrocytes to provide nerve growth factor to adrenal chromaffin cells grafted to the striatum
    • Cunningham LA, Hansen JT, Short MP, Bohn MC (1991) The use of genetically altered astrocytes to provide nerve growth factor to adrenal chromaffin cells grafted to the striatum. Brain Res 561:192-202
    • (1991) Brain Res , vol.561 , pp. 192-202
    • Cunningham, L.A.1    Hansen, J.T.2    Short, M.P.3    Bohn, M.C.4
  • 33
    • 0027050888 scopus 로고
    • Peripheral nerve segments promote consistent long-term survival of adrenal medulla transplants in the brain
    • Doering LC (1992) Peripheral nerve segments promote consistent long-term survival of adrenal medulla transplants in the brain. Exp Neurol 118:253-260
    • (1992) Exp Neurol , vol.118 , pp. 253-260
    • Doering, L.C.1
  • 34
    • 84911218507 scopus 로고
    • Early experience with intrastriatal adrenal medulla/nerve cografting in Parkinson’s disease
    • Watts RL, Freeman A, Graham S, Bakay RAE (1992) Early experience with intrastriatal adrenal medulla/nerve cografting in Parkinson’s disease. Restor Neurol Neurosci 4:194
    • (1992) Restor Neurol Neurosci , vol.4 , pp. 194
    • Watts, R.L.1    Freeman, A.2    Graham, S.3    Bakay, R.4
  • 36
    • 85027641998 scopus 로고
    • Fibroblast growth factors: What’s in a name?
    • Barid A (1993) Fibroblast growth factors: What’s in a name? Endocrinol 132:487-488
    • (1993) Endocrinol , vol.132 , pp. 487-488
    • Barid, A.1
  • 39
    • 0024521368 scopus 로고
    • Basic fibroblast growth factor promotes the survival and development of mesencephalic neurons in culture
    • Ferrari G, Minozzi M-C, Toffano G, Leon A, Skaper SD (1989) Basic fibroblast growth factor promotes the survival and development of mesencephalic neurons in culture. Dev Biol 133:140-147
    • (1989) Dev Biol , vol.133 , pp. 140-147
    • Ferrari, G.1    Minozzi, M.-C.2    Toffano, G.3    Leon, A.4    Skaper, S.D.5
  • 40
    • 0026042368 scopus 로고
    • The neurotrophic effects of fibroblast growth factors on dopaminergic neurons in vitro are mediated by mesencephalic glia
    • Engele J, Bohn MC (1991) The neurotrophic effects of fibroblast growth factors on dopaminergic neurons in vitro are mediated by mesencephalic glia. J Neurosci 11:3070-3078
    • (1991) J Neurosci , vol.11 , pp. 3070-3078
    • Engele, J.1    Bohn, M.C.2
  • 41
    • 0027407368 scopus 로고
    • Mitogenic effects of bFGF on embryonic mesencephalic dopaminergic neurones
    • Mayer E, Dunnett SB, Fawcett JW (1993) Mitogenic effects of bFGF on embryonic mesencephalic dopaminergic neurones. Dev Brain Res 72:253-258
    • (1993) Dev Brain Res , vol.72 , pp. 253-258
    • Mayer, E.1    Dunnett, S.B.2    Fawcett, J.W.3
  • 43
    • 0011386910 scopus 로고
    • Organisation of septo-hippocampal neurons and their regulation by trophic factors produced by astrocytes
    • Hunter AJ, Clark M, Academic Press, London
    • Patel AJ, Kiss J, Gray G (1992) Organisation of septo-hippocampal neurons and their regulation by trophic factors produced by astrocytes, in Neurodegeneration (Hunter AJ, Clark M, eds), pp 59-80. Academic Press, London
    • (1992) Neurodegeneration , pp. 59-80
    • Patel, A.J.1    Kiss, J.2    Gray, G.3
  • 44
    • 0027285510 scopus 로고
    • GDNF: A glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons
    • Lin L-FH, Doherty DH, Lile JD, Bektesh S, Collins F (1993) GDNF: A glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 260:1130-1132
    • (1993) Science , vol.260 , pp. 1130-1132
    • Lin, L.-F.1    Doherty, D.H.2    Lile, J.D.3    Bektesh, S.4    Collins, F.5
  • 45
    • 0025025025 scopus 로고
    • Basic fibroblast growth factor enhances survival and sprouting of fetal dopaminergic cells implanted in the denervated rat caudate-putamen: Preliminary observations
    • Steinbusch HWM, Vermeulen RJ, Tonnaer JADM (1990) Basic fibroblast growth factor enhances survival and sprouting of fetal dopaminergic cells implanted in the denervated rat caudate-putamen: Preliminary observations. Prog Brain Res 82:81-86
    • (1990) Prog Brain Res , vol.82 , pp. 81-86
    • Steinbusch, H.1    Vermeulen, R.J.2    Tonnaer, J.3
  • 46
    • 0027236053 scopus 로고
    • Basic FGF promotes the survival of embryonic ventral mesencephalic dopaminergic neurones. II. Effects on nigral transplants in vivo
    • Mayer E, Fawcett JW, Dunnett SB (1993) Basic FGF promotes the survival of embryonic ventral mesencephalic dopaminergic neurones. II. Effects on nigral transplants in vivo. Neurosci, in press
    • (1993) Neurosci
    • Mayer, E.1    Fawcett, J.W.2    Dunnett, S.B.3
  • 47
    • 0025034302 scopus 로고
    • MPTP- treated young mice but not aging mice show partial recovery of the nigrostriatal dopaminergic system by stereotaxic injection of acidic fibroblast growth factor (AFGF)
    • Date I, Notter MFD, Felten SY, Felten DL (1990) MPTP- treated young mice but not aging mice show partial recovery of the nigrostriatal dopaminergic system by stereotaxic injection of acidic fibroblast growth factor (aFGF). Brain Res 526:156-160
    • (1990) Brain Res , vol.526 , pp. 156-160
    • Date, I.1    Notter, M.2    Felten, S.Y.3    Felten, D.L.4
  • 48
    • 0025440265 scopus 로고
    • Basic FGF reverses chemical and morphological deficits in the nigrostriatal system of MPTP-treated mice
    • Otto D, Unsicker K (1990) Basic FGF reverses chemical and morphological deficits in the nigrostriatal system of MPTP-treated mice. J Neurosci 10:1912-1921
    • (1990) J Neurosci , vol.10 , pp. 1912-1921
    • Otto, D.1    Unsicker, K.2
  • 49
    • 0027081071 scopus 로고
    • Protection from l-methyl-4- phenyl pyridium (MPP +) toxicity and stimulation of regrowth of MPP+ -damaged dopaminergic fibers by treatment of mesencephalic cultures with EGF and basic FGF
    • + -damaged dopaminergic fibers by treatment of mesencephalic cultures with EGF and basic FGF. Brain Res 599:83-97
    • (1992) Brain Res , vol.599 , pp. 83-97
    • Park, T.H.1
  • 50
    • 0026766860 scopus 로고
    • The nerve growth factor family of receptors
    • Meakin SO, Shooter EM (1992) The nerve growth factor family of receptors. Trends Neurosci 15:323-331
    • (1992) Trends Neurosci , vol.15 , pp. 323-331
    • Meakin, S.O.1    Shooter, E.M.2
  • 51
    • 0026578776 scopus 로고
    • Brain- derived neurotrophic factor and neurotrophin-3 mRNAs are expressed in ventral midbrain regions containing dopaminergic neurons
    • Gall CM, Gold SJ, Isackson PJ, Seroogy KB (1992) Brain- derived neurotrophic factor and neurotrophin-3 mRNAs are expressed in ventral midbrain regions containing dopaminergic neurons. Mol Cell Neurosci 3:56-63
    • (1992) Mol Cell Neurosci , vol.3 , pp. 56-63
    • Gall, C.M.1    Gold, S.J.2    Isackson, P.J.3    Seroogy, K.B.4
  • 52
    • 0025838347 scopus 로고
    • Effect of CNTF on low affinity NGF receptor expression by cultured neurons from different rat brain regions
    • Magal E, Burnham P, Varon S (1991) Effect of CNTF on low affinity NGF receptor expression by cultured neurons from different rat brain regions. J Neurosci Res 30: 560-566
    • (1991) J Neurosci Res , vol.30 , pp. 560-566
    • Magal, E.1    Burnham, P.2    Varon, S.3
  • 53
    • 0026022504 scopus 로고
    • Promotion of central cholinergic and dopaminergic neuron differentiation by brain-derived neurotrophic factor but not neurotrophin-3
    • Knüsel B, Winslow JW, Rosenthal A, Burton LE, Seid DP, Nikolics K, Hefti F (1991) Promotion of central cholinergic and dopaminergic neuron differentiation by brain-derived neurotrophic factor but not neurotrophin-3. Proc Natl Acad Sci USA 88:961-965
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 961-965
    • Knüsel, B.1    Winslow, J.W.2    Rosenthal, A.3    Burton, L.E.4    Seid, D.P.5    Nikolics, K.6    Hefti, F.7
  • 54
    • 0027389046 scopus 로고
    • The nature of the trophic action of brain-derived neurotrophic factor, des(1-3)- insulin-like growth factor-1 and basic fibroblast growth factor on mesencephalic dopaminergic neurons developing in culture
    • Beck KD, Kniisel B, Hefti F (1993) The nature of the trophic action of brain-derived neurotrophic factor, des(1-3)- insulin-like growth factor-1 and basic fibroblast growth factor on mesencephalic dopaminergic neurons developing in culture. Neurosci 52:855-866
    • (1993) Neurosci , vol.52 , pp. 855-866
    • Beck, K.D.1    Kniisel, B.2    Hefti, F.3
  • 55
    • 0026689954 scopus 로고
    • Brain derived neurotrophic factor protects dopamine neurons against 6-hydroxydopamine and N-methyl-4- phenylpyridium ion toxicity: Involvement of the glutathione system
    • Spina MB, Squinto SP, Miller J, Lindsay RM, Hyman C (1992) Brain derived neurotrophic factor protects dopamine neurons against 6-hydroxydopamine and N-methyl-4- phenylpyridium ion toxicity: Involvement of the glutathione system. J Neurochem 59:99-106
    • (1992) J Neurochem , vol.59 , pp. 99-106
    • Spina, M.B.1    Squinto, S.P.2    Miller, J.3    Lindsay, R.M.4    Hyman, C.5
  • 56
    • 0026574673 scopus 로고
    • Brain derived neurotrophic factor administration protects basal forebrain cholinergic but not nigral dopaminergic neurons from degenerative changes after axotomy in the adult rat brain
    • Knüsel B, Beck KD, Winslow JW, Rosenthal A, Burton LE, Widner HR, Nikolics K, Hefti F (1992) Brain derived neurotrophic factor administration protects basal forebrain cholinergic but not nigral dopaminergic neurons from degenerative changes after axotomy in the adult rat brain. J Neurosci 12:4391-4402
    • (1992) J Neurosci , vol.12 , pp. 4391-4402
    • Knüsel, B.1    Beck, K.D.2    Winslow, J.W.3    Rosenthal, A.4    Burton, L.E.5    Widner, H.R.6    Nikolics, K.7    Hefti, F.8
  • 57
  • 59
    • 0027407015 scopus 로고
    • Chronic intranigral administration of brain-derived neurotrophic factor produces striatal dopaminergic hypofunction in unlesioned adult rats and fails to attenuate the decline of striatal dopaminergic function following medial forebrain bundle transection
    • Lapchak PA, Beck KD, Araujo DM, Irwin I, Langston JW, Hefti F (1993) Chronic intranigral administration of brain-derived neurotrophic factor produces striatal dopaminergic hypofunction in unlesioned adult rats and fails to attenuate the decline of striatal dopaminergic function following medial forebrain bundle transection. Neurosci 53:639-650
    • (1993) Neurosci , vol.53 , pp. 639-650
    • Lapchak, P.A.1    Beck, K.D.2    Araujo, D.M.3    Irwin, I.4    Langston, J.W.5    Hefti, F.6
  • 60
    • 0025265681 scopus 로고
    • Selective and non-selective stimulation of central cholinergic and dopaminergic development in vitro by nerve growth factor, basic fibroblast growth factor, epidermal growth factor, insulin and insulin-like growth factors I and II
    • Knüsel B, Michel PP, Schwaber JS, Hefti F (1990) Selective and non-selective stimulation of central cholinergic and dopaminergic development in vitro by nerve growth factor, basic fibroblast growth factor, epidermal growth factor, insulin and insulin-like growth factors I and II. J Neurosci 10:558-570
    • (1990) J Neurosci , vol.10 , pp. 558-570
    • Knüsel, B.1    Michel, P.P.2    Schwaber, J.S.3    Hefti, F.4
  • 61
    • 0021954503 scopus 로고
    • Monitoring of cell viability in suspensions of embryonic CNS tissue and its use as a criterion for intracerebral graft survival
    • Brundin P, Isacson O, Björklund A (1985) Monitoring of cell viability in suspensions of embryonic CNS tissue and its use as a criterion for intracerebral graft survival. Brain Res 331.251-259
    • (1985) Brain Res , vol.331 , pp. 251-259
    • Brundin, P.1    Isacson, O.2    Björklund, A.3
  • 62
    • 0023148062 scopus 로고
    • Afferent and efferent connections of striatal grafts implanted into ibotenic acid lesion striatum in adult rats
    • Pritzel M, Isacson O, Brundin P, Wiklund L, Björklund A (1986) Afferent and efferent connections of striatal grafts implanted into ibotenic acid lesion striatum in adult rats. Exp Brain Res 65:112-126
    • (1986) Exp Brain Res , vol.65 , pp. 112-126
    • Pritzel, M.1    Isacson, O.2    Brundin, P.3    Wiklund, L.4    Björklund, A.5
  • 64
    • 0025292905 scopus 로고
    • Effect of basic fibroblast growth factors on neurons cultured from various regions of postnatal rat brain
    • Matsuda S, Saito H, Nishiyama N (1990) Effect of basic fibroblast growth factors on neurons cultured from various regions of postnatal rat brain. Brain Res 520:310-316
    • (1990) Brain Res , vol.520 , pp. 310-316
    • Matsuda, S.1    Saito, H.2    Nishiyama, N.3
  • 65
    • 0022550672 scopus 로고
    • Differential regulation of cholinergic and peptidergic development in the rat striatum in culture
    • Kessler JA (1986) Differential regulation of cholinergic and peptidergic development in the rat striatum in culture. Dev Biol 113-77-89
    • (1986) Dev Biol , vol.113 , pp. 77-89
    • Kessler, J.A.1
  • 66
    • 0026486342 scopus 로고
    • Dopaminergic stimulation up-regulates the in vivo expression of brain-derived neurotrophic factor (BDNF) in the striatum
    • Okazawa H, Murata M, Watanabe M, Kamei M, Kanazawa I (1992) Dopaminergic stimulation up-regulates the in vivo expression of brain-derived neurotrophic factor (BDNF) in the striatum. FEBS 313:138-142
    • (1992) FEBS , vol.313 , pp. 138-142
    • Okazawa, H.1    Murata, M.2    Watanabe, M.3    Kamei, M.4    Kanazawa, I.5
  • 67
    • 0025790094 scopus 로고
    • Intracerebral implantation of nerve growth factor-producing fibroblasts protect striatum against neurotoxic levels of excitatory amino acids
    • Schumacher JM, Short MP, Hyman BT, Breakefield XO, Isacson O (1991) Intracerebral implantation of nerve growth factor-producing fibroblasts protect striatum against neurotoxic levels of excitatory amino acids. Neurosci 45:561-570
    • (1991) Neurosci , vol.45 , pp. 561-570
    • Schumacher, J.M.1    Short, M.P.2    Hyman, B.T.3    Breakefield, X.O.4    Isacson, O.5
  • 69
    • 0025911018 scopus 로고
    • Advances in Alzheimer’s disease
    • Katzman R, Saitoh T (1991) Advances in Alzheimer’s disease. FASEB J 5:278-286
    • (1991) FASEB J , vol.5 , pp. 278-286
    • Katzman, R.1    Saitoh, T.2
  • 70
    • 0026705242 scopus 로고
    • Treatment for Alzheimer’s disease?
    • Growdon JH (1992) Treatment for Alzheimer’s disease? N Engl J Med 327:1306-1308
    • (1992) N Engl J Med , vol.327 , pp. 1306-1308
    • Growdon, J.H.1
  • 71
    • 0025938569 scopus 로고
    • The basal forebrain-cortical cholinergic system: Interpreting the functional consequences of excitotoxic lesions
    • Dunnett SB, Everitt BJ, Robbins TW (1992) The basal forebrain-cortical cholinergic system: Interpreting the functional consequences of excitotoxic lesions. Trends Neurosci 14:494-501
    • (1992) Trends Neurosci , vol.14 , pp. 494-501
    • Dunnett, S.B.1    Everitt, B.J.2    Robbins, T.W.3
  • 72
    • 0020370303 scopus 로고
    • Septal transplants restore maze learning in rats with fimbria-fornix lesions
    • Dunnett SB, Low WC, Iversen SD, Stenevi U, Björklund A (1982) Septal transplants restore maze learning in rats with fimbria-fornix lesions. Brain Res 251:335-348
    • (1982) Brain Res , vol.251 , pp. 335-348
    • Dunnett, S.B.1    Low, W.C.2    Iversen, S.D.3    Stenevi, U.4    Björklund, A.5
  • 73
    • 0025266166 scopus 로고
    • Acetylcholine release from intrahippocampal septal grafts is under control of the host brain
    • Nilsson OG, Kalen P, Rosengren E, Björklund A (1990) Acetylcholine release from intrahippocampal septal grafts is under control of the host brain. Proc Natl Acad Sci USA 87:2647-2651
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 2647-2651
    • Nilsson, O.G.1    Kalen, P.2    Rosengren, E.3    Björklund, A.4
  • 74
    • 0026355994 scopus 로고
    • Neural transplants as a treatment for Alzheimer’s disease?
    • Dunnett SB (1991) Neural transplants as a treatment for Alzheimer’s disease? Psychol Med 21:825-830
    • (1991) Psychol Med , vol.21 , pp. 825-830
    • Dunnett, S.B.1
  • 75
    • 85027654203 scopus 로고
    • NGF withdrawal results in the death of developing but not mature septal cholinergic neurons in vitro: Protection by protein synthesis inhibition
    • Svendsen CN, Kew JNC, Staley K, Sofroniew MV (1993) NGF withdrawal results in the death of developing but not mature septal cholinergic neurons in vitro: Protection by protein synthesis inhibition. J Neurosci, in press
    • (1993) J Neurosci
    • Svendsen, C.N.1    Kew, J.2    Staley, K.3    Sofroniew, M.V.4
  • 77
    • 0026008812 scopus 로고
    • Recombinant human nerve growth factor infusions prevent cholinergic neuronal degeneration in the adult primate brain
    • Tuszynski MH, Sang H, Yoshida K, Gage FH (1991) Recombinant human nerve growth factor infusions prevent cholinergic neuronal degeneration in the adult primate brain. Ann Neurol 30:625-636
    • (1991) Ann Neurol , vol.30 , pp. 625-636
    • Tuszynski, M.H.1    Sang, H.2    Yoshida, K.3    Gage, F.H.4
  • 78
    • 0023643241 scopus 로고
    • Amelioration of cholinergic neuron atrophy and spatial memory in aged rat by nerve growth factor
    • Fischer W, Wictorin K, Björklund A, Williams LR, Varon S, Gage FH (1987) Amelioration of cholinergic neuron atrophy and spatial memory in aged rat by nerve growth factor. Nature 329:65-68
    • (1987) Nature , vol.329 , pp. 65-68
    • Fischer, W.1    Wictorin, K.2    Björklund, A.3    Williams, L.R.4    Varon, S.5    Gage, F.H.6
  • 79
    • 0025331508 scopus 로고
    • Nerve growth factor infusions combined with fetal hippocampal grafts enhance reconstruction of the lesioned septohippocampal projection
    • Tuszynski MH, Buzsaki G, Gage FH (1990) Nerve growth factor infusions combined with fetal hippocampal grafts enhance reconstruction of the lesioned septohippocampal projection. Neurosci 36:33-44
    • (1990) Neurosci , vol.36 , pp. 33-44
    • Tuszynski, M.H.1    Buzsaki, G.2    Gage, F.H.3
  • 80
    • 0026593442 scopus 로고
    • Neural transplants: Prospects for Alzheimer’s disease
    • Gage FH, Chen KS (1992) Neural transplants: Prospects for Alzheimer’s disease Curr Opin Neurol Neurosurg 5:94-99
    • (1992) Curr Opin Neurol Neurosurg , vol.5 , pp. 94-99
    • Gage, F.H.1    Chen, K.S.2
  • 81
    • 0026438936 scopus 로고
    • Does loss of nerve growth factor receptors precede loss of cholinergic neurons in Alzheimer’s Disease? An autoradiographic study in human striatum and basal forebrain
    • Strada O, Hirsch EC, Javoy-Agid F, Lehericy S, Ruberg M, Hauw J-J, Agid Y (1992) Does loss of nerve growth factor receptors precede loss of cholinergic neurons in Alzheimer’s Disease? An autoradiographic study in human striatum and basal forebrain J Neurosci 12:4766-4774
    • (1992) J Neurosci , vol.12 , pp. 4766-4774
    • Strada, O.1    Hirsch, E.C.2    Javoy-Agid, F.3    Lehericy, S.4    Ruberg, M.5    Hauw, J.-J.6    Agid, Y.7
  • 82
    • 0024990331 scopus 로고
    • Widespread expression of BDNF but not NT3 by target areas of basal forebram cholinergic neurons
    • Phillips HS, Hains JM, Laramee GR, Rosenthal A, Winslow JW (1990) Widespread expression of BDNF but not NT3 by target areas of basal forebram cholinergic neurons. Science 250:290-294
    • (1990) Science , vol.250 , pp. 290-294
    • Phillips, H.S.1    Hains, J.M.2    Laramee, G.R.3    Rosenthal, A.4    Winslow, J.W.5
  • 83
    • 0025168085 scopus 로고
    • Brain derived neurotrophic factor increase survival and differentiated functions of rat septal cholinergic neurons in culture
    • Alderson RF, Alterman AL, Barde Y-A, Lindsay RM (1990) Brain derived neurotrophic factor increase survival and differentiated functions of rat septal cholinergic neurons in culture Neuron 5:297-306
    • (1990) Neuron , vol.5 , pp. 297-306
    • Alderson, R.F.1    Alterman, A.L.2    Barde, Y.-A.3    Lindsay, R.M.4
  • 84
    • 0026378719 scopus 로고
    • The synthesis of nerve growth factor and brain derived neurotrophic factor in hippocampal and cortical neurons is regulated by specific transmitter systems
    • Thoenen H, Zafra F, Hengerer B, Lindholm D (1991) The synthesis of nerve growth factor and brain derived neurotrophic factor in hippocampal and cortical neurons is regulated by specific transmitter systems. Ann NY Acad Sci 638:86-90
    • (1991) Ann NY Acad Sci , vol.638 , pp. 86-90
    • Thoenen, H.1    Zafra, F.2    Hengerer, B.3    Lindholm, D.4
  • 85
    • 0026573196 scopus 로고
    • Septal cholinergic afferents regulate expression of brain derived neurotrophic factor and β-nerve growth factor mRNA in rat hippocampus
    • Lindefors N, Ernfors P, Falkenberg T, Persson H (1992) Septal cholinergic afferents regulate expression of brain derived neurotrophic factor and β-nerve growth factor mRNA in rat hippocampus. Exp Brain Res 88:78-90
    • (1992) Exp Brain Res , vol.88 , pp. 78-90
    • Lindefors, N.1    Ernfors, P.2    Falkenberg, T.3    Persson, H.4
  • 87
    • 0026625201 scopus 로고
    • BDNF and NGF treatment in lesioned rats: Effects on cholinergic function and weight gain
    • Lapchak PA, Hefti F (1992) BDNF and NGF treatment in lesioned rats: Effects on cholinergic function and weight gain. NeuroReport 3:405-408
    • (1992) Neuroreport , vol.3 , pp. 405-408
    • Lapchak, P.A.1    Hefti, F.2
  • 88
    • 0027537224 scopus 로고
    • BDNF protection of basal forebrain cholinergic neurons after axotomy: Complete protection of p75 NGFR-positive cells
    • Widmer HR, Knüsel B, Hefti F (1993) BDNF protection of basal forebrain cholinergic neurons after axotomy: Complete protection of p75 NGFR-positive cells. NeuroReport 4:363-366
    • (1993) Neuroreport , vol.4 , pp. 363-366
    • Widmer, H.R.1    Knüsel, B.2    Hefti, F.3
  • 89
    • 0027461725 scopus 로고
    • Did radicals strike Lou Gehrig?
    • McNamara JO, Fridovich I (1993) Did radicals strike Lou Gehrig? Nature 362:20-21
    • (1993) Nature , vol.362 , pp. 20-21
    • McNamara, J.O.1    Fridovich, I.2
  • 91
    • 0025931715 scopus 로고
    • Grafts of embryonic tissue into spinal cord: A possible strategy for treating neuromuscular disorders
    • Clowry G, Sieradzan K, Vrbová G (1991) Grafts of embryonic tissue into spinal cord: A possible strategy for treating neuromuscular disorders. Neuromusc Disord 1:87-92
    • (1991) Neuromusc Disord , vol.1 , pp. 87-92
    • Clowry, G.1    Sieradzan, K.2    Vrbová, G.3
  • 92
    • 0025306812 scopus 로고
    • Spinal cord transplants enhance the recovery of locomotor function after spinal cord injury at birth
    • Kunkel-Bagden E, Bregman BS (1990) Spinal cord transplants enhance the recovery of locomotor function after spinal cord injury at birth. Exp Brain Res 81:25-34
    • (1990) Exp Brain Res , vol.81 , pp. 25-34
    • Kunkel-Bagden, E.1    Bregman, B.S.2
  • 93
    • 0026507555 scopus 로고
    • Dependence of postnatal motoneurones on their targets: Review and hypothesis
    • Lowrie MB, Vrbová G (1992) Dependence of postnatal motoneurones on their targets: Review and hypothesis. Trends Neurosci 15:80-84
    • (1992) Trends Neurosci , vol.15 , pp. 80-84
    • Lowrie, M.B.1    Vrbová, G.2
  • 94
    • 84911223712 scopus 로고
    • The ability of isolated embryonic motoneurones grafted into rat spinal cord to express cholinergic markers and innervate skeletal muscle
    • Sieradzan K, Clowry G, Haynes L, Vrbová G (1992) The ability of isolated embryonic motoneurones grafted into rat spinal cord to express cholinergic markers and innervate skeletal muscle. Restor Neurol Neurosci 4:220
    • (1992) Restor Neurol Neurosci , vol.4 , pp. 220
    • Sieradzan, K.1    Clowry, G.2    Haynes, L.3    Vrbová, G.4
  • 96
    • 0027113861 scopus 로고
    • High hopes of a trophic factor
    • Oppenheim RW (1992) High hopes of a trophic factor. Nature 358:451-452
    • (1992) Nature , vol.358 , pp. 451-452
    • Oppenheim, R.W.1
  • 97
    • 0027067035 scopus 로고
    • Brain derived neurotrophic factor rescues spinal motor neurons after axotomy-induced cell death
    • Yan Q, Elliott J, Snider WD (1992) Brain derived neurotrophic factor rescues spinal motor neurons after axotomy-induced cell death. Nature 360:753-755
    • (1992) Nature , vol.360 , pp. 753-755
    • Yan, Q.1    Elliott, J.2    Snider, W.D.3
  • 98
    • 0027070473 scopus 로고
    • Brain derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section
    • Sendtner M, Holtman B, Kolbeck R, Thoenen H, Barde Y-A (1992) Brain derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section. Nature 360:757-759
    • (1992) Nature , vol.360 , pp. 757-759
    • Sendtner, M.1    Holtman, B.2    Kolbeck, R.3    Thoenen, H.4    Barde, Y.-A.5
  • 99
    • 0025514410 scopus 로고
    • Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: Comparison with other neurotrophic factors and cytokines
    • Arakawa Y, Sendtner M, Thoenen H (1990) Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: Comparison with other neurotrophic factors and cytokines. J Neurosci 10:3507-3515
    • (1990) J Neurosci , vol.10 , pp. 3507-3515
    • Arakawa, Y.1    Sendtner, M.2    Thoenen, H.3
  • 101
    • 0026667103 scopus 로고
    • Induction of motor neuron sprouting in vivo by ciliary neurotrophic factor and basic fibroblast growth factor
    • Gurney ME, Yamamoto H, Kwon Y (1992) Induction of motor neuron sprouting in vivo by ciliary neurotrophic factor and basic fibroblast growth factor. J Neurosci 12:3241-3247
    • (1992) J Neurosci , vol.12 , pp. 3241-3247
    • Gurney, M.E.1    Yamamoto, H.2    Kwon, Y.3
  • 102
    • 0027467471 scopus 로고
    • Neuronal differentiation factors/cytokines and synaptic plasticity
    • Patterson PH, Nawa H (1993) Neuronal differentiation factors/cytokines and synaptic plasticity. Cell 72 (Suppl):123-137
    • (1993) Cell , vol.72 , pp. 123-137
    • Patterson, P.H.1    Nawa, H.2
  • 103
    • 0026480188 scopus 로고
    • Neurotransmitters as neurotrophic factors: A new set of functions
    • Schwartz JP (1992) Neurotransmitters as neurotrophic factors: A new set of functions. Int Rev Neurobiol 34:1-23
    • (1992) Int Rev Neurobiol , vol.34 , pp. 1-23
    • Schwartz, J.P.1
  • 105
    • 0023865447 scopus 로고
    • Development and survival of neurons in dissociated fetal mesencephalic serum-free cell cultures: II. Modulatory effects of gangliosides
    • Leon A, Dal Toso R, Presti D, Benevegnù D, Facci L, Kirschner G, Tettamanti G, Toffano G (1988) Development and survival of neurons in dissociated fetal mesencephalic serum-free cell cultures: II. Modulatory effects of gangliosides. J Neurosci 8:746-753
    • (1988) J Neurosci , vol.8 , pp. 746-753
    • Leon, A.1    Dal Toso, R.2    Presti, D.3    Benevegnù, D.4    Facci, L.5    Kirschner, G.6    Tettamanti, G.7    Toffano, G.8
  • 106
    • 0026024226 scopus 로고
    • Interleukin-6 improves the survival of mesencephalic catecholaminergic and septal cholinergic neurons from postnatal, two-week-old rats in cultures
    • Hama T, Kushima Y, Miyamoto M, Kubota M, Takei N, Hatanaka H (1991) Interleukin-6 improves the survival of mesencephalic catecholaminergic and septal cholinergic neurons from postnatal, two-week-old rats in cultures. Neurosci 40:445-452
    • (1991) Neurosci , vol.40 , pp. 445-452
    • Hama, T.1    Kushima, Y.2    Miyamoto, M.3    Kubota, M.4    Takei, N.5    Hatanaka, H.6
  • 108
    • 0019864818 scopus 로고
    • Specific stimulation of in vitro maturation of mesencephalic dopaminergic neurones by striatal membranes
    • Prochiantz A, Daguet M-C, Herbet A, Glowinski J (1981) Specific stimulation of in vitro maturation of mesencephalic dopaminergic neurones by striatal membranes. Nature 293:570-572
    • (1981) Nature , vol.293 , pp. 570-572
    • Prochiantz, A.1    Daguet, M.-C.2    Herbet, A.3    Glowinski, J.4
  • 109
    • 0023854328 scopus 로고
    • Development and survival of neurons in dissociated mesencephalic serumfree cell cultures: I. Effects of cell density and of an adult mammalian striatal-derived neuronotrophic factor (SDNF)
    • Dal Toso D, Georgi O, Soranzo C, Kirschner G, Ferrari G, Favaron M, Benevegnù D, Presti D, Vicini S, Toffano G, Azzone GF, Leon A (1988) Development and survival of neurons in dissociated mesencephalic serumfree cell cultures: I. Effects of cell density and of an adult mammalian striatal-derived neuronotrophic factor (SDNF) J Neurosci 8:733-745
    • (1988) J Neurosci , vol.8 , pp. 733-745
    • Dal Toso, D.1    Georgi, O.2    Soranzo, C.3    Kirschner, G.4    Ferrari, G.5    Favaron, M.6    Benevegnù, D.7    Presti, D.8    Vicini, S.9    Toffano, G.10    Azzone, G.F.11    Leon, A.12
  • 110
    • 0026773316 scopus 로고
    • Mesencephalic type I astrocytes mediate the survival of substantia nigra dopaminergic neurons in culture
    • O’Malley EK, Sieber B-A, Black IB, Dreyfus CF (1992) Mesencephalic type I astrocytes mediate the survival of substantia nigra dopaminergic neurons in culture. Brain Res 582:65-70
    • (1992) Brain Res , vol.582 , pp. 65-70
    • O’Malley, E.K.1    Sieber, B.-A.2    Black, I.B.3    Dreyfus, C.F.4
  • 111
    • 0023719528 scopus 로고
    • Basic and acidic fibroblast growth factors have trophic effects on neurons from multiple CNS regions
    • Walicke PA (1988) Basic and acidic fibroblast growth factors have trophic effects on neurons from multiple CNS regions. J Neurosci 8:2618-2627
    • (1988) J Neurosci , vol.8 , pp. 2618-2627
    • Walicke, P.A.1
  • 113
    • 0025785581 scopus 로고
    • Acidic and basic fibroblast growth factors augment growth of fetal brain tissue grafts
    • Giacobini MMJ, Hoffer BJ, Zerbe G, Olson L (1991) Acidic and basic fibroblast growth factors augment growth of fetal brain tissue grafts. Exp Brain Res 86:73-81
    • (1991) Exp Brain Res , vol.86 , pp. 73-81
    • Giacobini, M.1    Hoffer, B.J.2    Zerbe, G.3    Olson, L.4
  • 114
    • 0026531499 scopus 로고
    • Ciliary neurotrophic factor prevents neuronal degeneration and promotes low affinity NGF receptor expression in the adult rat CNS
    • Hagg T, Quon D, Higaki J, Varon S (1992) Ciliary neurotrophic factor prevents neuronal degeneration and promotes low affinity NGF receptor expression in the adult rat CNS. Neuron 8:145-148
    • (1992) Neuron , vol.8 , pp. 145-148
    • Hagg, T.1    Quon, D.2    Higaki, J.3    Varon, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.