Protein kinase C: biochemical characteristics and role in melanocyte biology

Journal of Dermatological Science

Volumn 6, Issue 3, 1993, Pages 185-193

  Park, Hee Young ^a   Gilchrest, Barbara A ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Melanocytes; Melanogenesis; Phorbol esters; Protein kinase C

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; PHORBOL ESTER; PROTEIN KINASE C; PROTEIN KINASE INHIBITOR; SPHINGOSINE; STAUROSPORINE;

CELL PROLIFERATION; HUMAN; MELANOCYTE; MELANOGENESIS; PRIORITY JOURNAL; REVIEW;

ANIMAL; HUMAN; ISOMERISM; MELANOCYTES; PROTEIN KINASE C; SIGNAL TRANSDUCTION; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0027716024     PISSN: 09231811     EISSN: None     Source Type: Journal    
DOI: 10.1016/0923-1811(93)90037-P     Document Type: Review

References (68)

1. Selective proliferation of normal human melanocytes in vitro in the presence of phorbol ester and cholera toxin
2. Selective cultivation of human melanocytes from newborn and adult epidermis
3. The stimulation of normal human melanocyte proliferation in vitro by melanocyte growth factor from bovine brain
4. Induction of nerve growth factor receptors on cultured human melanocytes
5. Tumor-promoting activity of phorbol and four diesters of phorbol in mouse skin
6. The phorbol ester receptor: a phospholipid-regulated protein kinase
7. Differential down regulation of epidermal protein kinase C by 12-O-tetradecanoylphorbol-13-acetate and diacylglycerol: association with epidermal hyperplasia and tumor promotion
8. Human melanogenesis is stimulated by diacylglycerol
9. 4-induced human melanocyte growth are inhibited by different isoquinolinesulfonamides
10. The β isoform of protein kinase C stimulates human melanogenesis by activating tyrosinase in pigment cells
11. Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues
12. Turnover of inositol phospholipids and signal transduction
13. Phorbol diester receptor copurifies with protein kinase C
14. Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C
15. The molecular heterogeneity of protein kinase C and its implications for cellular regulation
16. Lipid activation of protein kinase C
17. Purification and characterization of a calcium-unresponsive, phorbol ester/phospholipid-activated protein kinase from porcine spleen
18. Isolation and characterization of δ-subspecies of protein kinase C from rat brain
19. Protein kinase C group B members PKC-delta, -epsilon, -zeta and PKC-L(eta). Comparison of properties of recombinant proteins in vitro and in vivo
20. Protein kinase C ξ subspecies from rat brain: its structure, expression, and properties
21. A phorbol ester receptor/protein kinase, nPKCη, a new member of the protein kinase C family predominantly expressed in lung and skin
22. Transmembrane signaling by interferon α involves diacylglycerol production and activation of the ϵ isoform of protein kinase C in Daudi cells
23. Altered growth regulation and enhanced tumorigenicity of NIH 3T3 fibroblasts transfected with protein kinase C-1 cDNA
24. Overexpression of protein kinase C β1 enhances phospholipase D activity and diacylglycerol formation in phorbol ester-stimulated rat fibroblasts
25. Cells that overproduce protein kinase C are more susceptible to transformation by an activated H-ras oncogene
26. Overexpression of protein kinase C in HT29 colon cancer cells causes growth inhibition and tumor suppression
27. Diacylglycerol modulates binding and phosphorylation of the epidermal growth factor receptor
28. 3 cells treated with phorbol 12-myristate 13-acetate
29. Protein kinase C activation by diacylglycerol second messengers
30. Proteolytic activation of protein kinase C: a physiological reaction
31. Structural basis of protein kinase C activation by diacyglycerols and tumor promoters
32. Early signals in the mitogenic response
33. Quantitation of protein kinase C by immunoblot-expression in different cell lines and response to phorbol esters
34. Immunological evidence for two physiological forms of protein kinase C
35. Differential down-regulation of protein kinase C isozymes
36. Protein serine/threonine kinases
37. The MARCKS family of cellular protein kinase C substrates
38. The MARCKS brothers: A family of protein kinase C substrates
39. Protein kinase C stimulates melanogenesis through phosphorylation of tyrosinase
40. Protein kinase C phosphorylation of the EGF receptor at a threonine residue close to the cytoplasmic residue close to the cytoplasmic face of the plasma membrane
41. Protein kinase C directly phosphorylates the insulin receptor in vitro and reduces its protein-tyrosinase kinase activity
42. Phosphorylation of ras oncogene product by protein kinase C
43. Antigen-induced secretion of histamine and the phosphorylation of myosin by protein kinase C in rat basophilic leukemia cells
44. Isolation and characterization of protein kinase C from Y-1 adrenal cell cytoskeleton
45. Intermediate filament reconstitution in vitro. The role of phosphorylation on the assembly-disassembly of desmin
46. Differential expression of protein kinase C and cAMP-dependent protein kinase in normal human melanocytes and malignant melanomas
47. Growth of human melanocyte cultures supported by 12-O-tetradecanoylphorbol-13-acetate is mediated through protein kinase C activation
48. A culture system for the study of human melanocyte physiology
49. Protein kinase C down-regulation, and not transient activation, correlates with melanocyte growth
50. bFGF is the putative natural growth factor for human melanocytes
51. Isolation of brain fibroblast growth factor by heparin-sepharose affinity chromtography: identity with pituitary fibroblast growth factor
52. FGF inactivates myogenic helix-loop-helix proteins through phosphorylation of a conserved protein kinase C site in their DNA-binding domains
53. Cytoskeletal events underlying dendrite formation by cultured pigment cells
54. 1 cells
55. Protein kinase C in rat brain synaptosomes
56. Association of the β isoform of protein kinase C with vimentin filaments
57. Activation of protein kinase C results in the displacement of its myristoylated, alanine-rich substrate from punctate structures in macrophage filopodia
58. Regulation of tyrosinase in human melanocytes grown in culture
59. Enzymatic control of pigmentation in mammals
60. Mammalian tyrosinase: Biosynthesis, processing, and modulation by melanocyte stimulating hormone
61. Induction of protein kinase C in mouse melanoma cells by retinoic acid
62. Increased expression of protein kinase Cα plays a key role in retinoic acid-induced melanoma differentiation
63. Ultraviolet radiation directly induces pigment production by cultured human melanocytes
64. Selective increase of the α subspecies of protein kinase C and inhibition of melanogenesis induced by retinoic acid in melanoma cells
65. Depletion of protein kinase C blocks alpha-melanocyte stimulating hormone-induced melanogenesis
66. Induction of c-fos but not c-myc in S-91 cells by melanization signals
67. Ultraviolet stimulated melanogenesis by human melanocytes is augmented by Di-Acyl glycerol but not TPA