-
1
-
-
0026716204
-
Biology of Tumor Metastasis
-
of special interest, See [5of special interest].
-
(1992)
Lancet
, vol.339
, pp. 1453-1457
-
-
Hart1
Saini2
-
2
-
-
0025301851
-
The Cellular Basis of Site-Specific Tumor Metastasis
-
(1990)
N Engl J Med
, vol.322
, pp. 605-612
-
-
Zetter1
-
5
-
-
0026469519
-
Adhesion Molecules and Tumor Cell Interaction with Endothelium and Subendothelial Matrix
-
of special interest, This paper and [1of special interest] are useful and broad-ranging reviews of the biology of tumor metastasis and the role of adhesion molecules in this process.
-
(1992)
Cancer Metastasis Rev
, vol.11
, pp. 353-375
-
-
Honn1
Tang2
-
7
-
-
0026249489
-
Fibronectin/Integrin Interaction Induces Tyrosine Phosphorylation of a 120 kD Protein
-
(1991)
Cell Regul
, vol.2
, pp. 951-964
-
-
Guan1
Trevethick2
Hynes3
-
10
-
-
0026674919
-
Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin.
-
of special interest, This paper and [9of special interest] describe the cloning and characterization of FAK, a novel cytoplasmic tyrosine kinase of approximately 125 kDa that localizes at focal adhesion sites.
-
(1992)
Proceedings of the National Academy of Sciences
, vol.89
, pp. 8481-8491
-
-
Hanks1
Calalb2
Harper3
Patel4
-
11
-
-
0027055575
-
Cell Adhesion or Integrin Clustering Increases Phosphorylation of a Focal Adhesion Associated Tyrosine Kinase
-
of special interest, See [13of special interest].
-
(1992)
J Biol Chem
, vol.267
, pp. 23439-23442
-
-
Kornberg1
Earp2
Parsons3
Schaller4
Juliano5
-
13
-
-
0026445719
-
Tyrosine Phosphorylation of Paxillin and pp125FAK Accompanies Cell Adhesion to Extraellular Matrix: a Role in Cytoskeletal Assembly
-
of special interest, References [11of special interest–13of special interest] demonstrate that pp125FAK is tyrosine-phosphorylated in response to integrin-mediated cell adhesion. These reports also explore various aspects of the relationship between pp125FAK, focal contact formation and cytoskeletal assembly.
-
(1992)
J Cell Biol
, vol.119
, pp. 893-903
-
-
Burridge1
Turner2
Romer3
-
14
-
-
0026476697
-
Focal Adhesion Kinase (p125FAK): a Point of Convergence in the Action of Neuropeptides, Integrins, and Oncogenes
-
of special interest, This interesting and timely review developed the hypothesis that pp125FAK is at the nexus of signaling pathways mediated by integrins, G protein coupled receptors, and src-family kinases.
-
(1992)
Cell
, vol.71
, pp. 891-894
-
-
Zachary1
Rosengurt2
-
15
-
-
0026759309
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Regulation of Focal Adhesion Associated Protein Tyrosine Kinase by Both Cellular Adhesion and Oncogenic Transformation
-
of special interest, This article explores the relationship between expression of oncogenes and tyrosine phosphorylation of pp125FAK.
-
(1992)
Nature
, vol.358
, pp. 690-692
-
-
Guan1
Shalloway2
-
16
-
-
0027459771
-
Signal transduction from the extracellular matrix
-
of special interest, This review provides a reasonably comprehensive and up-to-date discussion of the relationship between integrin signaling pathways and the regulation of gene expression.
-
(1992)
The Journal of Cell Biology
, vol.120
, pp. 577-585
-
-
Juliano1
Haskill2
-
17
-
-
0026457798
-
Tyrosine Phosphorylation of Membrane Proteins Mediates Cellular Invasion by Transformed Cells
-
of special interest, This report shows that pseudopodia of highly invasive tumor cells are very enriched in tyrosine-phosphorylated proteins.
-
(1992)
J Cell Biol
, vol.119
, pp. 1309-1325
-
-
Mueller1
Yeh2
Chen3
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21
-
-
0026756730
-
Integrins as a Primary Signal Transduction Molecule Regulating Monocyte Immediate Early Gene Induction
-
of special interest, This report demonstrates that stimulation of β1 (but not β2) integrins is sufficient to induce a variety of immediate-early genes in monocytes.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 9034-9038
-
-
Yurochko1
Liu2
Eierman3
Haskill4
-
22
-
-
0020643475
-
Cell Surface Interactions with Extracellular Materials
-
(1983)
Annu Rev Biochem
, vol.52
, pp. 761-799
-
-
Yamada1
-
24
-
-
0025214421
-
Elevated Levels of the α5β1 Fibronectin Receptor Deficient Chinese Hamster Ovary Cells
-
(1990)
Cell
, vol.60
, pp. 849-859
-
-
Giancotti1
Ruoslahti2
-
25
-
-
1542454824
-
Ectopic Expression of Integrin α5β1 Suppresses In Vitro Growth and Tumorigenicity of Human Colon Carcinoma Cells
-
of special interest, This report uses ectopic expression of the α5 subunit in colonic carcinoma cells and demonstrates effects on in vitro growth control, tumorigenesis in nude mice, and the expression of immediate-early genes involved in transcriptional control and cell proliferation.
-
(1992)
Mol Biol Cell
, vol.3
, pp. 232a
-
-
Varner1
Fisher2
Juliano3
-
26
-
-
0024534377
-
Changes in Integrin Receptors on Oncogenically Transformed Cells
-
(1989)
Cell
, vol.56
, pp. 281-290
-
-
Plantefaber1
Hynes2
-
29
-
-
0026786678
-
The Role of α5β1 Integrin Receptor in the Proliferative Response of Quiescent Human Melanoma Cells to Fibronectin
-
of special interest, The authors use melanoma cell lines with different levels of α5β1 expression to demonstrate that fibronectin or fibronectin fragments can have a positive growth regulatory effect on melanoma cells by acting through α5β1 integrin.
-
(1992)
Cancer Res
, vol.52
, pp. 4499-4506
-
-
Mortarini1
Gismondi2
Santoni3
Parmiani4
Anchini5
-
30
-
-
0027079933
-
Fibronectin Receptor Modulates Cyclin Dependent Kinase Activity
-
cdc2.
-
(1992)
J Biol Chem
, vol.267
, pp. 25744-25747
-
-
Symington1
-
33
-
-
0026631151
-
Involvement of Integrin αv Gene Expression in Human Melanoma Tumorigenicity
-
of special interest, This report uses an αv deficient cell line coupled with transfection with αv to demonstrate that this integrin subunit can increase the tumorigencity of melanoma cells in nude mice.
-
(1992)
J Clin Invest
, vol.89
, pp. 2018-2022
-
-
Felding-Habermann1
Mueller2
Romerdahl3
Cheresh4
-
34
-
-
0026542056
-
Integrin Expression in Human Melanoma Cells with Differing Invasive and Metastatic Properties
-
of special interest, The authors show that there are major differences in the expression of the αvβ3 integrin that correlate with the metastatic ability of melanoma cell lines.
-
(1992)
Clin Exp Metastasis
, vol.10
, pp. 111-120
-
-
Gehlsen1
Davis2
Sriramarao3
-
40
-
-
0025269239
-
Differences in the Biosynthesis and Localization of the Fibronectin Receptor in Normal and Transformed Cultured Human Cells
-
(1990)
Cancer Res
, vol.50
, pp. 1601-1607
-
-
Akiyama1
Larjava2
Yamada3
-
41
-
-
0025138216
-
Alterations in Integrin Receptor Expression on Chemically Transformed Human Cells: Specific Enhancement of Laminin and Collagen Receptor Complexes
-
(1990)
J Cell Biol
, vol.110
, pp. 481-489
-
-
Dedhar1
Saulnier2
-
48
-
-
0026730017
-
Alteration of stromal Protein and Integrin Expression in Breast — A Marker of Pre-Malignant Change
-
(1992)
J Pathol
, vol.167
, pp. 399-406
-
-
Jones1
Critchley2
Walker3
-
51
-
-
0025979573
-
Expression of α2, α6, and β1 Chains in Normal Mucosa and in Adenomas of the Colon, Colon Carcinomas and Their Liver Metastases
-
(1991)
Am J Pathol
, vol.139
, pp. 741-750
-
-
Koretz1
Schlag2
Boumsell3
Moller4
-
52
-
-
0025213155
-
Low Expression of Collagen Receptors in Moderate and Poorly Differentiated Colorectal Adenocarcinomas
-
(1990)
Br J Cancer
, vol.61
, pp. 636-638
-
-
Pignatelli1
Smith2
Bodmer3
-
57
-
-
0026441040
-
Mechanisms Underlying Abnormal Trafficking of Malignant Progenitors in Chronic Myelogenous Leukemia
-
of special interest, Provides interesting data supporting a role for integrins in the abnormal releases from bone marrow of chronic myelogenous leukemia cells.
-
(1992)
J Clin Invest
, vol.90
, pp. 1232-1241
-
-
Verfaillie1
McCarthy2
McGlave3
-
61
-
-
0026629402
-
Extracellular Matrix Receptors and Mouse Skin Carcinogenesis: Altered Expression Linked to Appearance of Early Markers of Tumor Progression
-
of special interest, References [27,28,35,45–56,57of special interest,58–60,61of special interest] describe patterns of integrin expression in tumors in man and in animals. These reports have the usual limitations of studies with clinical material in that they are rather descriptive and are often based on modest sample sizes. However, they are important in that they provide a picture of the actual situation in real tumors rather than in tumor cell lines. Of particular interest are [35,57of special interest,61of special interest]. This paper [61of special interest] is a study in murine skin tumors and provides an usuaualy detailed and comprehensive analysis of integrin expression in tumorigenesis.
-
(1992)
Cancer Res
, vol.52
, pp. 2966-2976
-
-
Tennenbaum1
Yuspa2
Grover3
Castronovo4
Sobel5
Yamada6
DeLuca7
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