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Volumn 34, Issue 10, 1993, Pages 1639-1642

1,1′-(azodicarbonyl)dipiperidine-tributylphosphine, a new reagent system for mitsunobu reaction

Author keywords

[No Author keywords available]

Indexed keywords

AMINE; DIAMIDE;

EID: 0027536014     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(93)85029-V     Document Type: Article
Times cited : (256)

References (16)
  • 1
    • 85077634689 scopus 로고
    • The Use of Diethyl Azodicarboxylate and Triphenylphosphine in Synthesis and Transformation of Natural Products
    • For a review
    • (1981) Synthesis , pp. 1-28
    • Mitsunobu1
  • 8
    • 84914360469 scopus 로고    scopus 로고
    • Commercially available ADDP (Aldrich, Inc. or Tokyo Chemical Industry Co., Ltd.) was recrystailized from benzene-hexane.
  • 9
    • 84914360468 scopus 로고    scopus 로고
    • 2 column chromatography.
  • 10
    • 84914360467 scopus 로고    scopus 로고
    • 7a)
  • 13
    • 84914360466 scopus 로고    scopus 로고
    • Under the standard Mitsunobu conditions (ROH: HA: azo compd: phosphine= 1:1:1:1), 6 and benzyl alcohol afforded N-benzyl-N-methyltosylamide in 45∼49% with ADDP-TPP in THF or benzene, and in 60% with ADDP-TBP in THF.
  • 16
    • 84914360465 scopus 로고    scopus 로고
    • Search for more versatile reagents is in progress in our laboratory as well as the practical synthesis of sec-amines.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.