Stimulation of insulin secretion by imidazoline compounds is not due to interaction with non‐adrenoceptor idazoxan binding sites

British Journal of Pharmacology

Volumn 108, Issue 2, 1993, Pages 312-317

  Brown, Colin A ^a   Loweth, Anne C ^a   Smith, Stephen A ^b   Morgan, Noel G ^a  

^a KEELE UNIVERSITY   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

efaroxan; idazoxan; insulin secretion; Islets of Langerhans; RX821001; 2 adrenoceptors

Indexed keywords

2 (2 METHOXY 1,4 BENZODIOXAN 2 YL) 2 IMIDAZOLINE; ALPHA 2 ADRENERGIC RECEPTOR; BRIMONIDINE; DIAZOXIDE; EFAROXAN; IDAZOXAN;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; INSULIN RELEASE; LIVER; MALE; NONHUMAN; PANCREAS; PRIORITY JOURNAL; RAT;

ADRENERGIC ALPHA-AGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANIMAL; BINDING SITES; COMPARATIVE STUDY; IMIDAZOLES; IN VITRO; INSULIN; ISLETS OF LANGERHANS; LIVER; MALE; MEMBRANES; RADIOLIGAND ASSAY; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, ALPHA; RECEPTORS, DRUG; SUPPORT, NON-U.S. GOV'T;

EID: 0027535908     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1993.tb12801.x     Document Type: Article

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