Pharmacokinetics of extracellular-superoxide dismutase in the vascular system

Free Radical Biology and Medicine

Volumn 14, Issue 2, 1993, Pages 185-190

  Karlsson, Kurt ^a   Sandström, Jan ^b   Edlund, Anders ^c   Edlund, Thomas ^b   Marklund, Stefan L ^a  

^a UMEÅ UNIVERSITY HOSPITAL   (Sweden)

^b Symbicom AB   (Sweden)

^c UMEÅ UNIVERSITY   (Sweden)

Author keywords

Free radicals; Oxygen radicals; Pharmacokinetics; Superoxide dismutase; Vascular wall

Indexed keywords

FREE RADICAL; OXYGEN RADICAL; PROTEOGLYCAN; RECOMBINANT PROTEIN; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL WALL; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; PRIORITY JOURNAL; RABBIT;

ANIMAL; BLOOD VESSELS; FEMALE; FREE RADICALS; HEPARIN; ISCHEMIA; KIDNEY; KINETICS; MALE; RABBITS; RECOMBINANT PROTEINS; REPERFUSION; SUPEROXIDE DISMUTASE; SUPEROXIDES; SUPPORT, NON-U.S. GOV'T; VARIATION (GENETICS);

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0027534262     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/0891-5849(93)90009-J     Document Type: Article

References (31)

1. Human copper-containing superoxide dismutase of high molecular weight
2. Expression of human extracellular-superoxide dismutase in chinese hamster ovary cells and characterization of the product
3. Superoxide dismutase in extracellular fluids
4. Heparin-induced release of extracellular-superoxide dismutase to human blood plasma
5. Extracellular-superoxide dismutase in the vascular system of mammals
6. Superoxide dismutase isoenzymes of the synovial fluid in rheumatoid arthritis and in reactive arthritides
7. Extracellular-superoxide dismutase in human tissues and human cell lines
8. Extracellular-superoxide dismutase and other superoxide dismutase isoenzymes in tissues from nine mammalian species
9. Binding of human extracellular-superoxide dismutase C to cultured cell lines and to blood cells
10. Plasma clearance of human extracellular-superoxide dismutase C in rabbits
11. Superoxide dismutase: Possible use in cardiovascular disease
12. Oxygen radicals in intestinal ischemia and reperfusion
13. The role of oxygen-derived free radicals in the pathogenesis of acute pancreatitis
14. Aspects of the structure, function and applications of superoxide dismutase
15. Superoxide dismutase: Pharmacological developments and applications
16. Recombinant human extracellular-superoxide dismutase reducs concentration of oxygen free radicals in the reperfused rat heart
17. Superoxide dismutase as an inhibitor of postischemic microvascular permeability increase in the hamster
18. Cardioprotective effects of recombinant human extracellular-superoxide dismutase type C in rat isolated heart subjected to ischemia and reperfusion
19. Endothelium-bound extracellular-superoxide dismutase type C reduces damage in reperfused ischemic rat hearts
20. Vascular bound recombinant extracellular-superoxide dismutase type C protects against the detrimental effects of superoxide radicals on endothelium-dependent arterial relaxation
21. Effects of recombinant human extracellular-superoxide dismutase type C on myocardial reperfusion injury in isolated cold-arrested rat hearts
22. Effects of recombinant human extracellular-superoxide dismutase type C on myocardial infarct size in pigs
23. The heparin-binding domain of extracellular-superoxide dismutase C, and formation of variants with reduced heparin-affinity
24. A simple method for the determination of the hemoglobin content of tissue homogenates
25. Solvent content of protein chrystals
26. The functional ultrastructure of the blood-lymph experiments using theoretical models
27. Orgotein
28. Interstitial equilibrations of superoxide dismutase correlates with its protective effect in the isolated rabbit heart