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Volumn 269, Issue 14, 1993, Pages 1829-1835

Anticytokine Strategies in the Treatment of the Systemic Inflammatory Response Syndrome

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 8; MONOCLONAL ANTIBODY; RECEPTOR ANTIBODY; RECEPTOR BLOCKING AGENT; TUMOR NECROSIS FACTOR;

EID: 0027528798     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.1993.03500140081040     Document Type: Article
Times cited : (384)

References (84)
  • 1
    • 0027077753 scopus 로고
    • Toward an epidemiology and natural history of SIRS (systemic inflammatory response syndrome)
    • Bone RC. Toward an epidemiology and natural history of SIRS (systemic inflammatory response syndrome). JAMA. 1992;268:3452-3455.
    • (1992) JAMA , vol.268 , pp. 3452-3455
    • Bone, R.C.1
  • 2
    • 0025933270 scopus 로고
    • Cytokines and their interactions with other inflammatory mediators in the pathogenesis of sepsis and septic shock
    • Billiau A, Vandekerckhove F. Cytokines and their interactions with other inflammatory mediators in the pathogenesis of sepsis and septic shock. Eur J Clin Invest. 1991;21:559-573.
    • (1991) Eur J Clin Invest , vol.21 , pp. 559-573
    • Billiau, A.1    Vandekerckhove, F.2
  • 3
    • 0026444426 scopus 로고
    • Platelet-activating factor biosynthesis by cultured mesangial cells is modulated by proteinase inhibitors
    • Biancone L, Tetta C, Turello E, et al. Platelet-activating factor biosynthesis by cultured mesangial cells is modulated by proteinase inhibitors. J Am Soc Nephrol. 1992;2:1251-1261.
    • (1992) J Am Soc Nephrol , vol.2 , pp. 1251-1261
    • Biancone, L.1    Tetta, C.2    Turello, E.3
  • 4
    • 0001862846 scopus 로고
    • Interleukin-8 and related cytokines
    • In: Gallin JI, Goldstein IM, Synderman R, eds. New York, NY: Raven Press;
    • Baggiolini M, Dewald B, Waltz A. Interleukin-8 and related cytokines. In: Gallin JI, Goldstein IM, Synderman R, eds. Inflammation: Basic Principles and Clinical Correlates. New York, NY: Raven Press; 1992:247-263.
    • (1992) Inflammation: Basic Principles and Clinical Correlates , pp. 247-263
    • Baggiolini, M.1    Dewald, B.2    Waltz, A.3
  • 5
    • 0022472749 scopus 로고
    • Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1
    • Dinarello CA, Cannon JG, Wolff SM, et al. Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1. J Exp Med. 1986;163:1433-1450.
    • (1986) J Exp Med , vol.163 , pp. 1433-1450
    • Dinarello, C.A.1    Cannon, J.G.2    Wolff, S.M.3
  • 6
    • 0344140225 scopus 로고
    • Interleukin 1 induces a shock-like state in rabbits: synergism with tumor necrosis factor and the effect of cyclooxygenase inhibition
    • Okusawa S, Gelfand JA, Ikejima T, Connolly RJ, Dinarello CA. Interleukin 1 induces a shock-like state in rabbits: synergism with tumor necrosis factor and the effect of cyclooxygenase inhibition. J Clin Invest. 1988;81:1162-1172.
    • (1988) J Clin Invest , vol.81 , pp. 1162-1172
    • Okusawa, S.1    Gelfand, J.A.2    Ikejima, T.3    Connolly, R.J.4    Dinarello, C.A.5
  • 7
    • 0022296893 scopus 로고
    • Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts
    • Dayer JM, Beutler B, Cerami A. Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts. J Exp Med. 1985;162:2163-2168.
    • (1985) J Exp Med , vol.162 , pp. 2163-2168
    • Dayer, J.M.1    Beutler, B.2    Cerami, A.3
  • 8
    • 0023118407 scopus 로고
    • Cachectin: more than a tumor necrosis factor
    • Beutler B, Cerami A. Cachectin: more than a tumor necrosis factor. N Engl J Med. 1987;316:379-385.
    • (1987) N Engl J Med , vol.316 , pp. 379-385
    • Beutler, B.1    Cerami, A.2
  • 9
    • 0023017916 scopus 로고
    • Cachectin/tumor necrosis factor regulates hepatic acute-phase gene expression
    • Perlmutter DH, Dinarello CA, Punsal PI, Colten HR. Cachectin/tumor necrosis factor regulates hepatic acute-phase gene expression. J Clin Invest. 1986;78:1349-1354.
    • (1986) J Clin Invest , vol.78 , pp. 1349-1354
    • Perlmutter, D.H.1    Dinarello, C.A.2    Punsal, P.I.3    Colten, H.R.4
  • 10
    • 0023472191 scopus 로고
    • Clinical pharmacology of recombinant human tumor necrosis factor in patients with advanced cancer
    • Chapman PB, Lester TJ, Casper ES, et al. Clinical pharmacology of recombinant human tumor necrosis factor in patients with advanced cancer. J Clin Oncol. 1987;5:1942-1951.
    • (1987) J Clin Oncol , vol.5 , pp. 1942-1951
    • Chapman, P.B.1    Lester, T.J.2    Casper, E.S.3
  • 11
    • 0024603761 scopus 로고
    • Interleukin-1 and its biologically related cytokines
    • Dinarello CA. Interleukin-1 and its biologically related cytokines. Adv Immunol. 1989;44:153-205.
    • (1989) Adv Immunol , vol.44 , pp. 153-205
    • Dinarello, C.A.1
  • 12
    • 0026633556 scopus 로고
    • Interleukin-1 alpha administered in a phase I trial to patients with advanced malignancies
    • Smith JW II, Urba W, Steis R, et al. Interleukin-1 alpha administered in a phase I trial to patients with advanced malignancies. J Clin Oncol. 1992;10:1141-1152.
    • (1992) J Clin Oncol , vol.10 , pp. 1141-1152
    • Smith, J.W.1    Urba, W.2    Steis, R.3
  • 13
    • 0025303041 scopus 로고
    • Activation of coagulation after administration of tumor necrosis factor to normal subjects
    • van der Poll T, Bueller HR, ten Cate H, et al. Activation of coagulation after administration of tumor necrosis factor to normal subjects. N Engl J Med. 1990;322:1622-1627.
    • (1990) N Engl J Med , vol.322 , pp. 1622-1627
    • van der Poll, T.1    Bueller, H.R.2    ten Cate, H.3
  • 14
    • 0025947758 scopus 로고
    • A comparison between the effects of interleukin-1α administration and sublethal endotoxemia in primates
    • Fischer E, Marano MA, Barber AE, et al. A comparison between the effects of interleukin-1α administration and sublethal endotoxemia in primates. Am J Physiol. 1991;261:R442-R449.
    • (1991) Am J Physiol , vol.261 , pp. R442-R449
    • Fischer, E.1    Marano, M.A.2    Barber, A.E.3
  • 15
    • 0025787689 scopus 로고
    • Interleukin 1 receptor antagonist: a new member of the interleukin family
    • Arend WP. Interleukin 1 receptor antagonist: a new member of the interleukin family. J Clin Invest. 1991;88:1445-1451.
    • (1991) J Clin Invest , vol.88 , pp. 1445-1451
    • Arend, W.P.1
  • 16
    • 0026702006 scopus 로고
    • Potential treatment of sepsis syndrome with cytokine-specific agents
    • Christman JW. Potential treatment of sepsis syndrome with cytokine-specific agents. Chest. 1992; 102:613-617.
    • (1992) Chest , vol.102 , pp. 613-617
    • Christman, J.W.1
  • 17
    • 0027916179 scopus 로고
    • The role of interleukin-1 in disease
    • Dinarello CA, Wolff SM. The role of interleukin-1 in disease. N Engl J Med. 1993;328:106-113.
    • (1993) N Engl J Med , vol.328 , pp. 106-113
    • Dinarello, C.A.1    Wolff, S.M.2
  • 18
    • 0025777448 scopus 로고
    • Interleukin-1 and interleukin-1 antagonism
    • Dinarello CA. Interleukin-1 and interleukin-1 antagonism. Blood. 1991;77:1627-1652.
    • (1991) Blood , vol.77 , pp. 1627-1652
    • Dinarello, C.A.1
  • 19
    • 0023601773 scopus 로고
    • Potentiation of IL-1 mediated B-cell killing by TNF: human tumor necrosis factor potentiates human interleukin 1-mediated rat pancreatic beta-cell cytotoxicity
    • Mandrup-Poulsen T, Bendtzen K, Dinarello CA, Nerup J. Potentiation of IL-1 mediated B-cell killing by TNF: human tumor necrosis factor potentiates human interleukin 1-mediated rat pancreatic beta-cell cytotoxicity. J Immunol. 1987;139:4077-4082.
    • (1987) J Immunol , vol.139 , pp. 4077-4082
    • Mandrup-Poulsen, T.1    Bendtzen, K.2    Dinarello, C.A.3    Nerup, J.4
  • 21
    • 0026530738 scopus 로고
    • Effects on leukocytes after injection of tumor necrosis factor into healthy humans
    • van der Poll T, van Deventer S, Hack CE, et al. Effects on leukocytes after injection of tumor necrosis factor into healthy humans. Blood. 1992;79: 693-698.
    • (1992) Blood , vol.79 , pp. 693-698
    • van der Poll, T.1    van Deventer, S.2    Hack, C.E.3
  • 22
    • 0025266645 scopus 로고
    • Prognostic values of tumor necrosis factor/cachectin, interleukin-1, interferon-alpha, and interferon-gamma in the serum of patients with septic shock: Swiss-Dutch J5 Immunoglobulin Study Group
    • Calandra T, Baumgartner JD, Grau GE, et al. Prognostic values of tumor necrosis factor/cachectin, interleukin-1, interferon-alpha, and interferon-gamma in the serum of patients with septic shock: Swiss-Dutch J5 Immunoglobulin Study Group. J Infect Dis. 1990;161:982-987.
    • (1990) J Infect Dis , vol.161 , pp. 982-987
    • Calandra, T.1    Baumgartner, J.D.2    Grau, G.E.3
  • 23
    • 0024451525 scopus 로고
    • Increased plasma levels of interleukin-6 in sepsis
    • Hack CE, DeGroot ER, Felt-Bersma RJF, et al. Increased plasma levels of interleukin-6 in sepsis. Blood. 1989;74:1704-1710.
    • (1989) Blood , vol.74 , pp. 1704-1710
    • Hack, C.E.1    DeGroot, E.R.2    Felt-Bersma, R.J.F.3
  • 24
    • 0026611677 scopus 로고
    • Role of interleukin-1 in infectious diseases
    • Dinarello CA. Role of interleukin-1 in infectious diseases. Immunol Rev. 1992;127:119-146.
    • (1992) Immunol Rev , vol.127 , pp. 119-146
    • Dinarello, C.A.1
  • 25
    • 0023893831 scopus 로고
    • Detection of circulating tumor necrosis factor after endotoxin administration
    • Michie HR, Manogue KR, Spriggs DR, et al. Detection of circulating tumor necrosis factor after endotoxin administration. N Engl J Med. 1988;318: 1481-1486.
    • (1988) N Engl J Med , vol.318 , pp. 1481-1486
    • Michie, H.R.1    Manogue, K.R.2    Spriggs, D.R.3
  • 26
    • 0025017232 scopus 로고
    • Circulating interleukin-1 and tumor necrosis factor in septic shock and experimental endotoxin fever
    • Cannon JG, Tompkins RG, Gelfand JA, et al. Circulating interleukin-1 and tumor necrosis factor in septic shock and experimental endotoxin fever. J Infect Dis. 1990;161:79-84.
    • (1990) J Infect Dis , vol.161 , pp. 79-84
    • Cannon, J.G.1    Tompkins, R.G.2    Gelfand, J.A.3
  • 28
    • 0025165135 scopus 로고
    • Two tumor necrosis factor-binding proteins purified from human urine: evidence for immunological cross-reactivity with cell surface tumor necrosis factor receptors
    • Engelmann H, Novick D, Wallach D. Two tumor necrosis factor-binding proteins purified from human urine: evidence for immunological cross-reactivity with cell surface tumor necrosis factor receptors. J Biol Chem. 1990;265:1531-1536.
    • (1990) J Biol Chem , vol.265 , pp. 1531-1536
    • Engelmann, H.1    Novick, D.2    Wallach, D.3
  • 29
    • 0026341998 scopus 로고
    • The IL-1 specific inhibitor from the M20 cell line is distinct from the IL-1 receptor antagonist
    • Barak V, Peritt D, Flechner I, et al. The IL-1 specific inhibitor from the M20 cell line is distinct from the IL-1 receptor antagonist. Lymphokine Cytokine Res. 1991;10:437-442.
    • (1991) Lymphokine Cytokine Res , vol.10 , pp. 437-442
    • Barak, V.1    Peritt, D.2    Flechner, I.3
  • 31
    • 0025954301 scopus 로고
    • Purification and characterization of a novel soluble receptor for interleukin-1
    • Symons JA, Eastgate JA, Duff GW. Purification and characterization of a novel soluble receptor for interleukin-1. J Exp Med. 1991;174:1251-1254.
    • (1991) J Exp Med , vol.174 , pp. 1251-1254
    • Symons, J.A.1    Eastgate, J.A.2    Duff, G.W.3
  • 32
    • 0026741275 scopus 로고
    • Tumor necrosis factor soluble receptors circulate during experimental and clinical inflammation and can protect against excessive tumor necrosis factor-α in vitro and in vivo
    • van Zee KJ, Kohno T, Fischer E, Rock CS, Moldawer LL, Lowry SF. Tumor necrosis factor soluble receptors circulate during experimental and clinical inflammation and can protect against excessive tumor necrosis factor-α in vitro and in vivo. Proc Natl Acad Sci U S A. 1992;89:4845-4849.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 4845-4849
    • van Zee, K.J.1    Kohno, T.2    Fischer, E.3    Rock, C.S.4    Moldawer, L.L.5    Lowry, S.F.6
  • 33
    • 0026762766 scopus 로고
    • Interleukin-1 (IL-1) receptor blockade reduces endotoxin and Borrelia burgdorferi-stimulated IL-8 synthesis in human mononuclear cells
    • Porat R, Poutsiaka DD, Miller LC, Granowitz EV, Dinarello CA. Interleukin-1 (IL-1) receptor blockade reduces endotoxin and Borrelia burgdorferi-stimulated IL-8 synthesis in human mononuclear cells. FASEB J. 1992;6:2482-2486.
    • (1992) FASEB J , vol.6 , pp. 2482-2486
    • Porat, R.1    Poutsiaka, D.D.2    Miller, L.C.3    Granowitz, E.V.4    Dinarello, C.A.5
  • 34
    • 0023138520 scopus 로고
    • Modulation of endothelial cell functions by different molecular species of interleukin 1
    • Dejana E, Breviario F, Erroi A, et al. Modulation of endothelial cell functions by different molecular species of interleukin 1. Blood. 1987;69:695-969.
    • (1987) Blood , vol.69 , pp. 695-969
    • Dejana, E.1    Breviario, F.2    Erroi, A.3
  • 35
    • 0025845144 scopus 로고
    • Effects of arachidonic acid metabolites and interleukin-1 on platelet activating factor production by hepatic sinusoidal endothelial cells from mice
    • Mizoguchi Y, Ichikawa Y, Kioka K, Kawada N, Kobayashi K, Yamamoto S. Effects of arachidonic acid metabolites and interleukin-1 on platelet activating factor production by hepatic sinusoidal endothelial cells from mice. J Gastroenterol Hepatol. 1991;6:283-288.
    • (1991) J Gastroenterol Hepatol , vol.6 , pp. 283-288
    • Mizoguchi, Y.1    Ichikawa, Y.2    Kioka, K.3    Kawada, N.4    Kobayashi, K.5    Yamamoto, S.6
  • 36
    • 0023854087 scopus 로고
    • Regulation of fibroblast cyclooxygenase synthesis by interleukin-1
    • Raz A, Wyche A, Siegel N, Needleman P. Regulation of fibroblast cyclooxygenase synthesis by interleukin-1. J Biol Chem. 1988;263:3022-3028.
    • (1988) J Biol Chem , vol.263 , pp. 3022-3028
    • Raz, A.1    Wyche, A.2    Siegel, N.3    Needleman, P.4
  • 37
    • 0025973551 scopus 로고
    • Interleukin 1 induces prolonged L-arginine-dependent cyclic guanosine monophosphate and nitrite production in rat vascular smooth muscle cells
    • Beasley D, Schwartz JH, Brenner BM. Interleukin 1 induces prolonged L-arginine-dependent cyclic guanosine monophosphate and nitrite production in rat vascular smooth muscle cells. J Clin Invest. 1991;87:602-608.
    • (1991) J Clin Invest , vol.87 , pp. 602-608
    • Beasley, D.1    Schwartz, J.H.2    Brenner, B.M.3
  • 38
    • 0023763110 scopus 로고
    • Induction by toxic-shock-syndrome toxin-1 of a circulating tumor necrosis factor-like substance in rabbits and of immunoreactive tumor necrosis factor and interleukin-1 from human mononuclear cells
    • Ikejima T, Okusawa S, van der Meer JW, Dinarello CA. Induction by toxic-shock-syndrome toxin-1 of a circulating tumor necrosis factor-like substance in rabbits and of immunoreactive tumor necrosis factor and interleukin-1 from human mononuclear cells. J Infect Dis. 1988;158:1017-1025.
    • (1988) J Infect Dis , vol.158 , pp. 1017-1025
    • Ikejima, T.1    Okusawa, S.2    van der Meer, J.W.3    Dinarello, C.A.4
  • 39
    • 0026596550 scopus 로고
    • Streptococcal toxic shock syndrome: synthesis of tumor necrosis factor and interleukin-1 by monocytes stimulated with pyrogenic exotoxin A and streptolysin O
    • Hackett SP, Stevens DL. Streptococcal toxic shock syndrome: synthesis of tumor necrosis factor and interleukin-1 by monocytes stimulated with pyrogenic exotoxin A and streptolysin O. J Infect Dis. 1992;165:879-885.
    • (1992) J Infect Dis , vol.165 , pp. 879-885
    • Hackett, S.P.1    Stevens, D.L.2
  • 40
    • 0022411888 scopus 로고
    • Passive immunization against cachetin/tumor necrosis factor protects mice from lethal effect of endotoxin
    • Beutler B, Milsark IW, Cerami A. Passive immunization against cachetin/tumor necrosis factor protects mice from lethal effect of endotoxin. Science. 1985;229:869-871.
    • (1985) Science , vol.229 , pp. 869-871
    • Beutler, B.1    Milsark, I.W.2    Cerami, A.3
  • 41
    • 0023491364 scopus 로고
    • Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteremia
    • Tracey K, Fong Y, Hesse DG, et al. Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteremia. Nature. 1987;330:662-664.
    • (1987) Nature , vol.330 , pp. 662-664
    • Tracey, K.1    Fong, Y.2    Hesse, D.G.3
  • 42
    • 0023884204 scopus 로고
    • Participation of tumor necrosis factor in the mediation of gram negative bacterial lipopolysaccharide-induced injury in rabbits
    • Mathison JC, Wolfson E, Ulevitch RJ. Participation of tumor necrosis factor in the mediation of gram negative bacterial lipopolysaccharide-induced injury in rabbits. J Clin Invest. 1988;81:1925-1937.
    • (1988) J Clin Invest , vol.81 , pp. 1925-1937
    • Mathison, J.C.1    Wolfson, E.2    Ulevitch, R.J.3
  • 43
    • 0025225333 scopus 로고
    • Interleukin-1 receptor antagonist reduces mortality from endotoxin shock
    • Ohlsson K, Bjork P, Bergenfeldt M, Hageman R, Thompson RC. Interleukin-1 receptor antagonist reduces mortality from endotoxin shock. Nature. 1990;348:550-552.
    • (1990) Nature , vol.348 , pp. 550-552
    • Ohlsson, K.1    Bjork, P.2    Bergenfeldt, M.3    Hageman, R.4    Thompson, R.C.5
  • 44
    • 0025904893 scopus 로고
    • A recombinant human receptor antagonist to interleukin-1 improves survival after lethal endotoxemia in mice
    • Alexander HR, Doherty GM, Buresh CM, Venzon DJ, Norton JA. A recombinant human receptor antagonist to interleukin-1 improves survival after lethal endotoxemia in mice. J Exp Med. 1991;173: 1029-1032.
    • (1991) J Exp Med , vol.173 , pp. 1029-1032
    • Alexander, H.R.1    Doherty, G.M.2    Buresh, C.M.3    Venzon, D.J.4    Norton, J.A.5
  • 45
    • 0025852720 scopus 로고
    • A specific receptor antagonist for interleukin-1 prevents Escherichia coli-induced shock
    • Wakabayashi G, Gelfand JA, Burke JF, Thompson RC, Dinarello CA. A specific receptor antagonist for interleukin-1 prevents Escherichia coli-induced shock. FASEB J. 1991;5:338-343.
    • (1991) FASEB J , vol.5 , pp. 338-343
    • Wakabayashi, G.1    Gelfand, J.A.2    Burke, J.F.3    Thompson, R.C.4    Dinarello, C.A.5
  • 46
    • 0026772736 scopus 로고
    • IL-1 receptor blockade improves survival and hemodynamic performance in E coli septic shock, but fails to alter host responses to sublethal endotoxemia
    • Fischer E, Marano MA, van Zee KJ, et al. IL-1 receptor blockade improves survival and hemodynamic performance in E coli septic shock, but fails to alter host responses to sublethal endotoxemia. J Clin Invest. 1992;89:1551-1557.
    • (1992) J Clin Invest , vol.89 , pp. 1551-1557
    • Fischer, E.1    Marano, M.A.2    van Zee, K.J.3
  • 47
    • 0021837926 scopus 로고
    • Homogeneous interferon-inducing 22K factor is related to endogenous pyrogen and interleukin-1
    • Van Damme J, De Ley M, Opdenakker G, Billiau A, De Somer P. Homogeneous interferon-inducing 22K factor is related to endogenous pyrogen and interleukin-1. Nature. 1985;314:266-268.
    • (1985) Nature , vol.314 , pp. 266-268
    • Van Damme, J.1    De Ley, M.2    Opdenakker, G.3    Billiau, A.4    De Somer, P.5
  • 49
    • 0025108171 scopus 로고
    • Preliminary report: effects of interleukin-1 on platelet counts
    • Tewari A, Buhles WC Jr, Starnes HF Jr. Preliminary report: effects of interleukin-1 on platelet counts. Lancet. 1990;336:712-714.
    • (1990) Lancet , vol.336 , pp. 712-714
    • Tewari, A.1    Buhles, W.C.2    Starnes, H.F.3
  • 50
    • 0023574619 scopus 로고
    • Gluco-corticoids inhibit transcriptional and post-transcriptional expression of interleukin 1 in U937 cells
    • Knudsen PJ, Dinarello CA, Strom TB. Gluco-corticoids inhibit transcriptional and post-transcriptional expression of interleukin 1 in U937 cells. J Immunol. 1987;139:4129-4134.
    • (1987) J Immunol , vol.139 , pp. 4129-4134
    • Knudsen, P.J.1    Dinarello, C.A.2    Strom, T.B.3
  • 51
    • 0025651251 scopus 로고
    • TGF-beta regulates production of growth factors and TGF-beta by human peripheral blood monocytes
    • McCartney FN, Mizel D, Wong H, Wahl L, Wahl S. TGF-beta regulates production of growth factors and TGF-beta by human peripheral blood monocytes. Growth Factors. 1990;4:27-35.
    • (1990) Growth Factors , vol.4 , pp. 27-35
    • McCartney, F.N.1    Mizel, D.2    Wong, H.3    Wahl, L.4    Wahl, S.5
  • 53
    • 0026503448 scopus 로고
    • Coordinated anti-inflammatory effects of interleukin 4: interleukin 4 suppresses interleukin 1 production but up-regulates gene expression and synthesis of interleukin 1 receptor antagonist
    • Vannier E, Miller LC, Dinarello CA. Coordinated anti-inflammatory effects of interleukin 4: interleukin 4 suppresses interleukin 1 production but up-regulates gene expression and synthesis of interleukin 1 receptor antagonist. Proc Nati Acad Sci U S A. 1992;89:4076-4080.
    • (1992) Proc Nati Acad Sci U S A , vol.89 , pp. 4076-4080
    • Vannier, E.1    Miller, L.C.2    Dinarello, C.A.3
  • 54
    • 0023688206 scopus 로고
    • Cellular and molecular regulation of tumor necrosis factor alpha production by pentoxifylline
    • Streiter RM, Remick PA, Ward PA, et al. Cellular and molecular regulation of tumor necrosis factor alpha production by pentoxifylline. Biochem Biophys Res Commun. 1988;155:1230-1236.
    • (1988) Biochem Biophys Res Commun , vol.155 , pp. 1230-1236
    • Streiter, R.M.1    Remick, P.A.2    Ward, P.A.3
  • 55
    • 0025302466 scopus 로고
    • Regulation of alloreactivity in vivo by a soluble form of the interleukin-1 receptor
    • Fanslow WC, Sims JE, Sassenfeld H, et al. Regulation of alloreactivity in vivo by a soluble form of the interleukin-1 receptor. Science. 1990;248:739-742.
    • (1990) Science , vol.248 , pp. 739-742
    • Fanslow, W.C.1    Sims, J.E.2    Sassenfeld, H.3
  • 56
    • 0024307648 scopus 로고
    • A tumor necrosis factor-binding protein purified to homogeneity from human urine protects cells from tumor necrosis factor toxicity
    • Engelmann H, Aderka D, Rubinstein M, Rotman D, Wallach D. A tumor necrosis factor-binding protein purified to homogeneity from human urine protects cells from tumor necrosis factor toxicity. J Biol Chem. 1989;264:11974-11980.
    • (1989) J Biol Chem , vol.264 , pp. 11974-11980
    • Engelmann, H.1    Aderka, D.2    Rubinstein, M.3    Rotman, D.4    Wallach, D.5
  • 57
    • 0025290397 scopus 로고
    • Interleukin 1 receptor blockade attenuates the host inflammatory response
    • Gershenwald JE, Fong YM, Fahey TJ III, et al. Interleukin 1 receptor blockade attenuates the host inflammatory response. Proc Natl Acad Sci USA. 1990;87:4966-4970.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 4966-4970
    • Gershenwald, J.E.1    Fong, Y.M.2    Fahey, T.J.3
  • 58
    • 0026517239 scopus 로고
    • Molecular cloning of the interleukin-1 beta converting enzyme
    • Cerretti DP, Kozlosky C, Mosley B, et al. Molecular cloning of the interleukin-1 beta converting enzyme. Science. 1992;256:97-100.
    • (1992) Science , vol.256 , pp. 97-100
    • Cerretti, D.P.1    Kozlosky, C.2    Mosley, B.3
  • 59
    • 0026507126 scopus 로고
    • A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes
    • Thornberry NA, Bull HG, Calaycay JR, et al. A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes. Nature. 1992;356:768-774.
    • (1992) Nature , vol.356 , pp. 768-774
    • Thornberry, N.A.1    Bull, H.G.2    Calaycay, J.R.3
  • 60
    • 0026056197 scopus 로고
    • Blocking IL-1: effects of IL-1 receptor antagonist in vitro and in vivo
    • Dinarello CA, Thompson RC. Blocking IL-1: effects of IL-1 receptor antagonist in vitro and in vivo. Immunol Today. 1991;12:404-410.
    • (1991) Immunol Today , vol.12 , pp. 404-410
    • Dinarello, C.A.1    Thompson, R.C.2
  • 61
    • 0342639834 scopus 로고
    • Interleukin-1 receptor antagonist blocks staphylococcal induced shock in rabbits
    • Aiura K, Gelfand JA, Wakabayashi G, et al. Interleukin-1 receptor antagonist blocks staphylococcal induced shock in rabbits. Cytokine. 1991;3: 498.
    • (1991) Cytokine , vol.3 , pp. 498
    • Aiura, K.1    Gelfand, J.A.2    Wakabayashi, G.3
  • 63
    • 0026928357 scopus 로고
    • Pharmacokinetics, safety, and immunomodulatory effects of human recombinant interleukin-1 receptor antagonist in healthy humans
    • Granowitz EV, Porat R, Mier JW, et al. Pharmacokinetics, safety, and immunomodulatory effects of human recombinant interleukin-1 receptor antagonist in healthy humans. Cytokine. 1992;4: 353-360.
    • (1992) Cytokine , vol.4 , pp. 353-360
    • Granowitz, E.V.1    Porat, R.2    Mier, J.W.3
  • 64
    • 0025786074 scopus 로고
    • Circulating interleukin-1 receptor antagonist levels during experimental endotoxemia in humans
    • Granowitz EV, Santos A, Poutsiaka DD, et al. Circulating interleukin-1 receptor antagonist levels during experimental endotoxemia in humans. Lancet. 1991;338:1423-1424.
    • (1991) Lancet , vol.338 , pp. 1423-1424
    • Granowitz, E.V.1    Santos, A.2    Poutsiaka, D.D.3
  • 65
    • 0026753370 scopus 로고
    • Interleukin-1 receptor antagonist circulates in experimental inflammation and in human disease
    • Fischer E, Van Zee KJ, Marano MA, et al. Interleukin-1 receptor antagonist circulates in experimental inflammation and in human disease. Blood. 1992;79:2196-2200.
    • (1992) Blood , vol.79 , pp. 2196-2200
    • Fischer, E.1    Van Zee, K.J.2    Marano, M.A.3
  • 66
    • 0026330925 scopus 로고
    • Modulation of cell proliferation and cytokine production in acute myeloblastic leukemia by interleukin-1 receptor antagonist and lack of its expression by leukemic cells
    • Rambaldi A, Torcia M, Bettoni S, et al. Modulation of cell proliferation and cytokine production in acute myeloblastic leukemia by interleukin-1 receptor antagonist and lack of its expression by leukemic cells. Blood. 1991;78:3248-3253.
    • (1991) Blood , vol.78 , pp. 3248-3253
    • Rambaldi, A.1    Torcia, M.2    Bettoni, S.3
  • 67
    • 0027397839 scopus 로고
    • Balance of synovial fluid IL-1β and IL-1 receptor antagonist and recovery from Lyme arthritis
    • Miller LC, Lynch EA, Isa S, Logan JW Dinarello CA, Steere AC. Balance of synovial fluid IL-1β and IL-1 receptor antagonist and recovery from Lyme arthritis. Lancet. 1993;341:146-148.
    • (1993) Lancet , vol.341 , pp. 146-148
    • Miller, L.C.1    Lynch, E.A.2    Isa, S.3    Logan, J.W.4    Dinarello, C.A.5    Steere, A.C.6
  • 68
    • 84945706768 scopus 로고    scopus 로고
    • IL-1 receptor antagonist can either protect or enhance the lethality of Klebsiella pneumoniae sepsis in newborn rats
    • In press
    • Mancilla J, Garcia P, Dinarello CA. IL-1 receptor antagonist can either protect or enhance the lethality of Klebsiella pneumoniae sepsis in newborn rats. Infect Immun. In press.
    • Infect Immun
    • Mancilla, J.1    Garcia, P.2    Dinarello, C.A.3
  • 69
    • 4243149446 scopus 로고
    • Recombinant soluble TNF receptor proteins inhibit LPS-induced lethality in mice
    • Lesslauer W, Tabuchi H, Gentz M, et al. Recombinant soluble TNF receptor proteins inhibit LPS-induced lethality in mice. Cytokine. 1991;3: 497.
    • (1991) Cytokine , vol.3 , pp. 497
    • Lesslauer, W.1    Tabuchi, H.2    Gentz, M.3
  • 70
    • 0025963717 scopus 로고
    • The intratracheal administration of endotoxin and cytokines, III: the interleukin-1 (IL-1) receptor antagonist inhibits endotoxin- and IL-1-induced acute inflammation
    • Ulich TR, Yin SM, Guo KZ, del Castillo J, Eisenberg SP, Thompson RC. The intratracheal administration of endotoxin and cytokines, III: the interleukin-1 (IL-1) receptor antagonist inhibits endotoxin- and IL-1-induced acute inflammation. Am J Pathol. 1991;138:521-524.
    • (1991) Am J Pathol , vol.138 , pp. 521-524
    • Ulich, T.R.1    Yin, S.M.2    Guo, K.Z.3    del Castillo, J.4    Eisenberg, S.P.5    Thompson, R.C.6
  • 71
    • 0025976452 scopus 로고
    • An interleukin-1 receptor antagonist blocks lipopolysaccharide-induced colony-stimulating factor production and early endotoxin tolerance
    • Henricson BE, Neta R, Vogel SN. An interleukin-1 receptor antagonist blocks lipopolysaccharide-induced colony-stimulating factor production and early endotoxin tolerance. Infect Immun. 1991; 59:1188-1191.
    • (1991) Infect Immun , vol.59 , pp. 1188-1191
    • Henricson, B.E.1    Neta, R.2    Vogel, S.N.3
  • 72
    • 0025986570 scopus 로고
    • Inhibition of interleukin-1 by interleukin-1 receptor antagonist prevents graft versus host disease
    • McCarthy PL, Abhyankar S, Neben S, et al. Inhibition of interleukin-1 by interleukin-1 receptor antagonist prevents graft versus host disease. Blood. 1991;78:1915-1918.
    • (1991) Blood , vol.78 , pp. 1915-1918
    • McCarthy, P.L.1    Abhyankar, S.2    Neben, S.3
  • 73
    • 0025082527 scopus 로고
    • Antibodies to a soluble form of a tumor necrosis factor (TNF) receptor have TNF-like activity
    • Engelmann H, Holtmann H, Brakebusch C, et al. Antibodies to a soluble form of a tumor necrosis factor (TNF) receptor have TNF-like activity. J Biol Chem. 1990;265:14497-14504.
    • (1990) J Biol Chem , vol.265 , pp. 14497-14504
    • Engelmann, H.1    Holtmann, H.2    Brakebusch, C.3
  • 74
    • 0025943512 scopus 로고
    • Recombinant soluble tumor necrosis factor receptor proteins protect mice from lipopolysaccharide-induced lethality
    • Lesslauer W, Tabuchi H, Gentz R, Brockhaus M. Recombinant soluble tumor necrosis factor receptor proteins protect mice from lipopolysaccharide-induced lethality. Eur J Immunol. 1991;21: 2883-2886.
    • (1991) Eur J Immunol , vol.21 , pp. 2883-2886
    • Lesslauer, W.1    Tabuchi, H.2    Gentz, R.3    Brockhaus, M.4
  • 75
    • 0026737258 scopus 로고
    • Release of soluble receptors for tumor necrosis factor (TNF) in relation to circulating TNF during experimental endotoxemia
    • Spinas GA, Keller U, Brockhaus M. Release of soluble receptors for tumor necrosis factor (TNF) in relation to circulating TNF during experimental endotoxemia. J Clin Invest. 1992;90:533-536.
    • (1992) J Clin Invest , vol.90 , pp. 533-536
    • Spinas, G.A.1    Keller, U.2    Brockhaus, M.3
  • 76
  • 77
    • 0026009871 scopus 로고
    • Increased serum levels of soluble receptors for tumor necrosis in cancer patients
    • Aderka D, Engelmann H, Hornik V, et al. Increased serum levels of soluble receptors for tumor necrosis in cancer patients. Cancer Res. 1991;51: 5602-5607.
    • (1991) Cancer Res , vol.51 , pp. 5602-5607
    • Aderka, D.1    Engelmann, H.2    Hornik, V.3
  • 78
    • 0026754027 scopus 로고
    • Phase I-II trial of a monoclonal anti-tumor necrosis factor alpha antibody for the treatment of refractory severe acute graft-versus-host disease
    • Herve P, Flesch M, Tiberghien P, et al. Phase I-II trial of a monoclonal anti-tumor necrosis factor alpha antibody for the treatment of refractory severe acute graft-versus-host disease. Blood. 1992; 79:3362-3368.
    • (1992) Blood , vol.79 , pp. 3362-3368
    • Herve, P.1    Flesch, M.2    Tiberghien, P.3
  • 79
    • 0023878325 scopus 로고
    • A low dose of recombinant interleukin 1 protects granulocytopenic mice from lethal gram-negative infection
    • van der Meer JWM, Barza M, Wolff SM, Dinarello CA. A low dose of recombinant interleukin 1 protects granulocytopenic mice from lethal gram-negative infection. Proc Nati Acad Sci U S A. 1988; 85:1620-1623.
    • (1988) Proc Nati Acad Sci U S A , vol.85 , pp. 1620-1623
    • van der Meer, J.W.M.1    Barza, M.2    Wolff, S.M.3    Dinarello, C.A.4
  • 80
    • 0023926860 scopus 로고
    • Sensitization and desensitization to lethal effects of tumor necrosis factor and IL-1
    • Wallach D, Holtmann H, Engelmann H, Nophar Y. Sensitization and desensitization to lethal effects of tumor necrosis factor and IL-1. J Immunol. 1988;140:2994-2999.
    • (1988) J Immunol , vol.140 , pp. 2994-2999
    • Wallach, D.1    Holtmann, H.2    Engelmann, H.3    Nophar, Y.4
  • 81
    • 0026585007 scopus 로고
    • Anti-tumor necrosis factor antibody therapy fails to prevent lethality after cecal ligation and puncture or endotoxemia
    • Eskandari MK, Bolgos G, Miller C, Nguyen DT, DeForge LE, Remick DG. Anti-tumor necrosis factor antibody therapy fails to prevent lethality after cecal ligation and puncture or endotoxemia. J Immunol. 1992;148:2724-2730.
    • (1992) J Immunol , vol.148 , pp. 2724-2730
    • Eskandari, M.K.1    Bolgos, G.2    Miller, C.3    Nguyen, D.T.4    DeForge, L.E.5    Remick, D.G.6
  • 82
    • 0026589636 scopus 로고
    • Anti-tumor necrosis factor antibodies suppress cell-mediated immunity in vivo
    • Bromberg JS, Chavin KD, Kunkel SL. Anti-tumor necrosis factor antibodies suppress cell-mediated immunity in vivo. J Immunol. 1992;148:3412-3417.
    • (1992) J Immunol , vol.148 , pp. 3412-3417
    • Bromberg, J.S.1    Chavin, K.D.2    Kunkel, S.L.3
  • 84
    • 9044245047 scopus 로고
    • A study evaluating the safety and efficacy of human recombinant interleukin-1 receptor antagonist in the treatment of patients with sepsis syndrome
    • March 23 Brussels, Belgium
    • Fisher CJ Jr, Dhalnaut J-F, Pribble JP, Knaus WA, and the IL-1 Receptor Antagonist Study Group. A study evaluating the safety and efficacy of human recombinant interleukin-1 receptor antagonist in the treatment of patients with sepsis syndrome. Presented at the 13th International Symposium on Intensive Care and Emergency Medicine; March 23, 1993; Brussels, Belgium.
    • (1993) Presented at the 13th International Symposium on Intensive Care and Emergency Medicine
    • Fisher, C.J.1    Dhalnaut, J.-F.2    Pribble, J.P.3    Knaus, W.A.4


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