Toxicity of oxidised low density lipoprotein towards mouse peritoneal macrophages in vitro

Atherosclerosis

Volumn 98, Issue 1, 1993, Pages 17-24

  Reid, V C ^a   Mitchinson, M J ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

d,l alpha tocopherol; LDL; Macrophages; Oxidation; Toxicity; Vitamin E

Indexed keywords

ALPHA TOCOPHEROL; LOW DENSITY LIPOPROTEIN;

ANIMAL EXPERIMENT; ARTICLE; ATHEROSCLEROSIS; CORONARY ARTERY DISEASE; MACROPHAGE; MALE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL;

ADENINE; ANIMAL; CELLS, CULTURED; LIPID PEROXIDATION; LIPOPROTEINS, LDL; MACROPHAGES; MICE; MICE, INBRED BALB C; OXIDATION-REDUCTION; PERITONEAL CAVITY; SUPPORT, NON-U.S. GOV'T; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

EID: 0027525873     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/0021-9150(93)90219-K     Document Type: Article

References (23)

1. Macrophages and ceroid in atherosclerosis
2. Beyond cholesterol. Modifications of low density lipoprotein that increase its atherogenicity
3. Modifications of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids
4. Oxidatively modified low density lipoproteins. A potential role in recruitment and retention of monocytes/macrophages during atherogenesis
5. Lipoprotein oxidation and lipoprotein-induced cytotoxicity
6. Low density lipoprotein cytotoxicity induced by free radical peroxidation of lipid
7. Monocytes and neutrophils oxidize low density lipoprotein making it cytotoxic
8. Identification of macrophages and smooth muscle cells in human atherosclerosis using monoclonal antibodies
9. Cellular damage in mouse peritoneal macrophages exposed to cholesteryl linoleate
10. Oxidised low density lipoprotein induces ceroid accumulation by murine peritoneal macrophages in vitro
11. The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum
12. Protein measurement with the folin phenol reagent
13. The stimulatory effects of carbon tetrachloride and other halogenoalkanes on peroxidative reactions in rat liver fractions in vitro
14. Oxidation of low density lipoprotein enhances its potential to increase intracellular free calcium concentration in vascular smooth muscle cells
15. LDL-induced cytotoxicity and its inhibition by anti-oxidant treatment in cultured human endothelial cells and fibroblasts
16. Oxygen radicals and human disease
17. Modulation of ceroid accumulation in macrophages in vitro
18. Spontaneously occurring angiotoxic derivatives of cholesterol
19. Connective tissue responses to oxysterols
20. Oxidation of cholesteryl linoleate by monocyte-macrophages in vitro
21. Lipid peroxide and transition metals are required for the toxicity of oxidised low density lipopro tein to cultured endothelial cells
22. Stimulation of lipid peroxidation and hydroxyl radical generation by the contents of human atherosclerotic lesions
23. The oxidative modification of low density lipoproteins by macrophages