Human immunodeficiency virus type 1-specific [2',5'-bis-O-(tert- butyldimethylsilyl)-β-D-ribofuranosyl]-3'-spiro-5''-(4''-amino-1'',2''- oxathiole-2'',2''-dioxide)-purine analogues show a resistance spectrum that is different from that of the human immunodeficiency virus type 1-specific non-nucleoside analogues

Molecular Pharmacology

Volumn 43, Issue 1, 1993, Pages 109-114

  Balzarini, J ^a   Velazquez, S ^a   San Felix, A ^a   Karlsson, A ^a   Perez Perez , M J ^a   Camarasa, M J ^a   De Clercq, E ^a  

^a REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; BENZODIAZEPINE DERIVATIVE; NEVIRAPINE; PURINE NUCLEOSIDE DERIVATIVE; PYRIDONE DERIVATIVE; PYRIMIDINE NUCLEOSIDE DERIVATIVE; RNA DIRECTED DNA POLYMERASE;

ANTIVIRAL ACTIVITY; ARTICLE; DRUG CLASSIFICATION; DRUG MECHANISM; DRUG RESISTANCE; DRUG SELECTIVITY; DRUG STRUCTURE; ENZYME INHIBITION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; PRIORITY JOURNAL; STRAIN DIFFERENCE; VIRUS REPLICATION;

AMINO ACID SEQUENCE; ANTIVIRAL AGENTS; BASE SEQUENCE; DRUG RESISTANCE; HIV-1; HIV-1 REVERSE TRANSCRIPTASE; HUMAN; HYPOXANTHINES; MOLECULAR SEQUENCE DATA; MUTATION; RNA-DIRECTED DNA POLYMERASE; SPIRO COMPOUNDS; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, NON-U.S. GOV'T; THYMIDINE;

EID: 0027524005     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (0)