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Volumn 12, Issue 13, 1993, Pages 5057-5064
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Conformational shifts propagate from the oligomerization domain of p53 to its tetrameric DNA binding domain and restore DNA binding to select p53 mutants
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Author keywords
Conformational shift; DNA binding; Oligomerization; p53; Tumor suppressor
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Indexed keywords
DNA BINDING PROTEIN;
MUTANT PROTEIN;
PROTEIN P53;
ARTICLE;
CONTROLLED STUDY;
DNA BINDING;
HUMAN;
PRIORITY JOURNAL;
PROTEIN CONFORMATION;
PROTEIN DNA BINDING;
PROTEIN DOMAIN;
SITE DIRECTED MUTAGENESIS;
AMINO ACID SEQUENCE;
BINDING SITES;
DNA-BINDING PROTEINS;
GENES, P53;
HUMAN;
IN VITRO;
MACROMOLECULAR SYSTEMS;
MOLECULAR SEQUENCE DATA;
MUTATION;
OLIGODEOXYRIBONUCLEOTIDES;
PROTEIN BINDING;
PROTEIN CONFORMATION;
PROTEIN P53;
STRUCTURE-ACTIVITY RELATIONSHIP;
SUPPORT, NON-U.S. GOV'T;
SUPPORT, U.S. GOV'T, P.H.S.;
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EID: 0027521114
PISSN: 02614189
EISSN: None
Source Type: Journal
DOI: None Document Type: Article |
Times cited : (193)
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References (0)
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