Growth-regulatory effects of sensory neuropeptides, epidermal growth factor, insulin, and somatostatin on the non-transformed intestinal epithelial cell line IEC-6 and the colon cancer cell line HT 29

Scandinavian Journal of Gastroenterology

Volumn 28, Issue 10, 1993, Pages 879-884

  Bjork J ^a   Nilsson, J ^a   Hultcrantz, R ^a   Johansson, C ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Growth factors; Growth regulation; HT29 cells; IEC 6 cells; Neuropeptides

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; EPIDERMAL GROWTH FACTOR; GROWTH FACTOR; INSULIN; NEUROKININ A; NEUROPEPTIDE; PEPTIDE YY; SOMATOSTATIN 14; SUBSTANCE P; VASOACTIVE INTESTINAL POLYPEPTIDE;

ANIMAL CELL; ARTICLE; CELL LINE; COLON CANCER; DOSE RESPONSE; GROWTH REGULATION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMAL; CALCITONIN GENE-RELATED PEPTIDE; CELL DIVISION; CELL LINE, TRANSFORMED; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; COLONIC NEOPLASMS; DNA, NEOPLASM; DOSE-RESPONSE RELATIONSHIP, DRUG; EPIDERMAL GROWTH FACTOR; EPITHELIUM; GASTROINTESTINAL HORMONES; HUMAN; INSULIN; INTESTINES; NEUROKININ A; NEURONS, AFFERENT; NEUROPEPTIDES; PEPTIDE YY; PEPTIDES; RATS; SOMATOSTATIN; SUBSTANCE P; SUPPORT, NON-U.S. GOV'T; TRANSFORMING GROWTH FACTOR BETA; VASOACTIVE INTESTINAL PEPTIDE;

EID: 0027517455     PISSN: 00365521     EISSN: None     Source Type: Journal    
DOI: 10.3109/00365529309103129     Document Type: Article

References (30)

1. Cell population kinetics in the intestinal epithelium of the mouse
2. The role of cell renewal in ontogeny of the intestine. II. Regulation of cell proliferation in adult, fetal and neonatal intestine
3. Establishment and characterization of intestinal epithelial cell cultures
4. Regulation of intestinal epithelial cell growth by transforming growth factor type β
5. Effects of growth factors on an intestinal epithelial cell line: transforming growth factor β inhibits proliferation and stimulates differentiation
6. The effects of gastrin, epidermal growth factor, and somatostatin on DNA synthesis in a small intestinal crypt cell line (IEC-6)
7. Modulation of epidermal growth factor induced cell proliferation and receptor binding by insulin in cultured intestinal epithelial cells
8. Somatostatin immunoreactive nerve fibers in close association with capillaries in the small intestine
9. Effects of gastrin, proglumide, and somatostatin on growth of human colon cancer
10. Is polyamine synthesis involved in the proliferative response of the intestinal epithelium to urogastrone-epidermal growth factor?
11. Effect of somatostatin on normal and gastric-stimulated cell proliferation in the gastric and intestinal mucosae of the rat
12. Negative control by Sandostatin on pancreatic and duodenal growth: a possible implication of insulin-like growth factor-1
13. Contradistinctive growth responses of cultured rat intestinal epithelial cells to epidermal growth factor depending on cell population density
14. Somatostatin inhibits deoxyribonucleic acid synthesis induced by both thyrotropin and insulin-like growth factor-1 in FRTL5 cells
15. Synthesis of somatostatin by breast cancer cells and their inhibition by exogenous somatostatin and Sandostatin
16. Somatostatin inhibits vasoactive intestinal peptide stimulated cyclic adenosine monophosphate accumulation in GH pituitary cells
17. Somatostatin analogues inhibit growth of pancreatic cancer by stimulating tyrosine phosphatase
18. Characterization of somatostatin binding sites in cytosolic fraction of rat intestinal mucosa
19. Stimulation of connective tissue cell growth by substance P and substance K
20. Effects of substance P and substance K on the growth of cultured keratinoevtes
21. Substance P stimulates neovascularization in vivo and proliferation of cultured endothelial cells
22. Epidermal growth factor: effect on growth of a colon adenocarcinoma cell line
23. Growth-promoting effect, biological activity, and binding of insulin in human intestinal cancer cells in culture
24. Growth factor production bv human colon carcinoma cell lines
25. Proliferation of the human colon carcinoma cell line HT 29: autocrine growth and deregulated expression of c-myc oncogene
26. Substance P analogues function as bombesin receptor antagonists and inhibit small cell lung cancer clonal growth
27. Enhancement by vasoactive intestinal peptide of experimental carcinogenesis induced by azoxymethane in rat colon
28. Promotion of differentiation in human colon carcinoma cells by vasoactive intestinal polypeptide
29. Involvement of ornithine decarboxylase in the control of proliferation of the HT29 human colon cancer cell line. Effect of vasoactive intestinal peptide on enzyme activity
30. VIP receptor activity during HT 29–18 cell differentiation and rat intestinal development