Direct gene transfer with DNA-liposome complexes in melanoma: Expression, biologic activity, and lack of toxicity in humans

Proceedings of the National Academy of Sciences of the United States of America

Volumn 90, Issue 23, 1993, Pages 11307-11311

  Nabel, G J ^a   Nabel, E G ^a   Yang, Z Y ^a   Fox, B A ^a   Plautz, G E ^a   Gao, X ^a   Huang, L ^a   Shu, S ^a   Gordon, D ^a   Chang, A E ^a  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

gene therapy; human clinical trials; immunotherapy; major histocompatibility complex

Indexed keywords

DNA; DNA ANTIBODY; HLA B7 ANTIGEN; LIPOSOME; PLASMID DNA; RECOMBINANT PROTEIN;

ADULT; AGED; ARTICLE; CANCER IMMUNOTHERAPY; CANCER REGRESSION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; FEMALE; GENE EXPRESSION; GENE TARGETING; GENE TRANSFER; HUMAN; HUMAN CELL; INTRATUMORAL DRUG ADMINISTRATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MELANOMA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

AGED; BASE SEQUENCE; CYTOTOXICITY, IMMUNOLOGIC; DNA; DNA PRIMERS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENES, MHC CLASS I; HLA-B7 ANTIGEN; HUMAN; LIPOSOMES; MALE; MELANOMA; MIDDLE AGE; RNA, MESSENGER; SKIN NEOPLASMS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0027517321     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.90.23.11307     Document Type: Article

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