-
2
-
-
0025835310
-
Making antibody fragments using phage display libraries
-
CLACKSON, T., HOOGENBOOM, H R., GRIFFITHS, A.D. & WINTER, G. (1991). Making antibody fragments using phage display libraries. Nature, 352, 624-628.
-
(1991)
Nature
, vol.352
, pp. 624-628
-
-
Clackson, T.1
Hoogenboom, H.R.2
Griffiths, A.D.3
Winter, G.4
-
3
-
-
0025362523
-
In vivo tumour targeting of a recombinant single-chain antigen-binding protein
-
COLCHER, D., BIRD, R., ROSELLI, M., HARDMAN, K.D., JOHNSON, S., POPE, S., DODD, S., PANTOLIANO, M.W., MILENIC, D.E. & SCHLOM, J. (1990). In vivo tumour targeting of a recombinant single-chain antigen-binding protein. JNCI, 82, 1191-1197.
-
(1990)
JNCI
, vol.82
, pp. 1191-1197
-
-
Colcher, D.1
Bird, R.2
Roselli, M.3
Hardman, K.D.4
Johnson, S.5
Pope, S.6
Dodd, S.7
Pantoliano, M.W.8
Milenic, D.E.9
Schlom, J.10
-
4
-
-
0025095664
-
Interleukin-2 production by tumour cells bypasses t helper function in the generation of an antitumour response
-
FEARON, E.R., PARDOLL, D.M., ITAYA, T., GOLUMBEK, P., LEVITSKY, H I., SIMONS, J.W., KARASUYAMA, H., VOGELSTEIN, B. & FROST, P. (1990). Interleukin-2 production by tumour cells bypasses T helper function in the generation of an antitumour response. Cell, 60, 397-403.
-
(1990)
Cell
, vol.60
, pp. 397-403
-
-
Fearon, E.R.1
Pardoll, D.M.2
Itaya, T.3
Golumbek, P.4
Levitsky, H.I.5
Simons, J.W.6
Karasuyama, H.7
Vogelstein, B.8
Frost, P.9
-
5
-
-
0025877853
-
Genetic construction and characterization of a fusion protein consisting of a chimeric f(Ab’) with specificity for carcinomas and human il-2
-
FELL, HP., GAYLE, M.A., GROSMAIRE, L. & LEDBETTER, J.A. (1991). Genetic construction and characterization of a fusion protein consisting of a chimeric F(ab’) with specificity for carcinomas and human IL-2. J. Immunol., 146, 2446-2452.
-
(1991)
J. Immunol
, vol.146
, pp. 2446-2452
-
-
Fell, H.P.1
Gayle, M.A.2
Grosmaire, L.3
Ledbetter, J.A.4
-
6
-
-
0026572996
-
Antibody-targeted interleukin 2 stimulates t-cell killing of autologous tumor cells
-
GILLIES, S.D., REILLY, E.D., LO, K.M. & REISFEL, R.A. (1992). Antibody-targeted interleukin 2 stimulates T-cell killing of autologous tumor cells. Proc. Natl Acad. Sci. USA, 89, 1428-1432.
-
(1992)
Proc. Natl Acad. Sci. USA
, vol.89
, pp. 1428-1432
-
-
Gillies, S.D.1
Reilly, E.D.2
Lo, K.M.3
Reisfel, R.A.4
-
7
-
-
0018174365
-
T cell growth factor: Parameters of production and a quantative microassay for activity
-
GILLIS, S., FERM, M.M., OU, W. & SMITH, K.A. (1978). T cell growth factor: parameters of production and a quantative microassay for activity. J. Immunol., 120, 2027-2032.
-
(1978)
J. Immunol
, vol.120
, pp. 2027-2032
-
-
Gillis, S.1
Ferm, M.M.2
Ou, W.3
Smith, K.A.4
-
8
-
-
0017402665
-
Long term culture of tumour-specific cytotoxic t cells
-
GILLIS, S. & SMITH, K.A. (1977). Long term culture of tumour-specific cytotoxic T cells. Nature, 268, 154-156.
-
(1977)
Nature
, vol.268
, pp. 154-156
-
-
Gillis, S.1
Smith, K.A.2
-
9
-
-
0026050688
-
Histamine, leukotriene c4 and interleukin-2 increase antibody uptake into a human carcinoma xenograft model
-
HENNIGAN, T.W., BEGENT, R.H.J. & ALLEN-MERSH, T.G. (1991). Histamine, leukotriene C4 and interleukin-2 increase antibody uptake into a human carcinoma xenograft model. Br. J. Cancer., 64, 872-874.
-
(1991)
Br. J. Cancer
, vol.64
, pp. 872-874
-
-
Hennigan, T.W.1
Begent, R.H.J.2
Allen-Mersh, T.G.3
-
10
-
-
0004198722
-
Protein engineering of antibody binding sites: Recovery of specific activity in an anti-digoxin single-chain fv analogue produced in escherichia coli
-
HUSTON, J.S., LEVINSON, D., MUDGETT-HUNTER, M., TAI, M.-S., NOVOTNY, J., MARGOLIES, M.N., RIDGE, R.J., BRUCCOLERI, R E., HABER, E., CREA, R. & OPPERMAN, H. (1988). Protein engineering of antibody binding sites: recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli. Proc. Natl. Acad. Sci. USA, 85, 5879-5883.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 5879-5883
-
-
Huston, J.S.1
Levinson, D.2
Mudgett-Hunter, M.3
Tai, M.-S.4
Novotny, J.5
Margolies, M.N.6
Ridge, R.J.7
Bruccoleri, R.E.8
Haber, E.9
Crea, R.10
Opperman, H.11
-
11
-
-
0025906530
-
Protein engineering of diptheria-toxin-related interleukin-2 fusion toxins to increase cytotoxic potency for high affinity il-2-receptor bearing target cells. Prot
-
KIYOKAWA, T., WILLIAMS, D.P., SNIDER, C.E., STROM, T.B. & MURPHYS, J.R. (1991). Protein engineering of diptheria-toxin-related interleukin-2 fusion toxins to increase cytotoxic potency for high affinity IL-2-receptor bearing target cells. Prot. Eng in., 4, 463-468.
-
(1991)
Eng In
, vol.4
, pp. 463-468
-
-
Kiyokawa, T.1
Williams, D.P.2
Snider, C.E.3
Strom, T.B.4
Murphys, J.R.5
-
12
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage t4
-
LAEMMLI, U.K. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature, 227, 680-685.
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
13
-
-
0025979475
-
A chimeric il-2/ig molecule possesses the functional activity of both proteins
-
LANDOLF, N.F. (1991). A chimeric IL-2/Ig molecule possesses the functional activity of both proteins. J. Immunol., 146, 915-919.
-
(1991)
J. Immunol
, vol.146
, pp. 915-919
-
-
Landolf, N.F.1
-
14
-
-
0025733498
-
Enhanced tumour uptake of macromolecules induced by a novel vasoactive interleukin-2 immunoconjugate
-
LEBERTHON, B., KHAWLI, L.A., ALAUDDIN, M., MILLER, G.K., CHARAK, B.S., MASUMDER, A. & EPSTEIN, A.L. (1991). Enhanced tumour uptake of macromolecules induced by a novel vasoactive interleukin-2 immunoconjugate. Cancer Res., 51, 2694-2698.
-
(1991)
Cancer Res
, vol.51
, pp. 2694-2698
-
-
Leberthon, B.1
Khawli, L.A.2
Alauddin, M.3
Miller, G.K.4
Charak, B.S.5
Masumder, A.6
Epstein, A.L.7
-
15
-
-
0023410604
-
Characterization of the erwinia carotovora pelb gene and its product pectate lyase
-
LEI, S P., LIN, H.C., WANG, S.S., CALLAWAY, J. & WILCOX, G. (1987). Characterization of the Erwinia carotovora pelB gene and its product pectate lyase. J. Bact., 169, 4379-4383.
-
(1987)
J. Bact
, vol.169
, pp. 4379-4383
-
-
Lei, S.P.1
Lin, H.C.2
Wang, S.S.3
Callaway, J.4
Wilcox, G.5
-
16
-
-
0024121599
-
Cytotoxic activity of an interleukin-2-pseudomonas exotoxin chimeric protein produced in escherichia coli
-
LORDERBOUM-GALSKI, H., FITZGERALD, D., CHAUDARY, V., ALDHAYA, S. & PASTAN, I. (1988). Cytotoxic activity of an interleukin-2-Pseudomonas exotoxin chimeric protein produced in Escherichia coli. Proc. Natl Acad. Sci. USA, 85, 1922-1926.
-
(1988)
Proc. Natl Acad. Sci. USA
, vol.85
, pp. 1922-1926
-
-
Lorderboum-Galski, H.1
Fitzgerald, D.2
Chaudary, V.3
Aldhaya, S.4
Pastan, I.5
-
17
-
-
84944285022
-
High dose recombinant interleukin 2 in the treatment of patients with disseminated cancer
-
LOTZE, M.T., CHANG, A.G., SEIPP, C.A., SIMPSON, C., VETTO, J.T. & ROSENBERG, S.A. (1986). High dose recombinant interleukin 2 in the treatment of patients with disseminated cancer. J. Am. Assoc., 256, 3117-3124.
-
(1986)
J. Am. Assoc
, vol.256
, pp. 3117-3124
-
-
Lotze, M.T.1
Chang, A.G.2
Seipp, C.A.3
Simpson, C.4
Vetto, J.T.5
Rosenberg, S.A.6
-
18
-
-
0026317443
-
By-passing immunization. Human antibodies from v-gene libraries displayed on phage
-
MARKS, J.D., HOOGENBOOM, H.R., BONNERT, T.P., MCCAFFERTY, J., GRIFFITH, D. & WINTER, G. (1991). By-passing immunization. Human antibodies from V-gene libraries displayed on phage. J. Mol. Biol., 222, 581-597.
-
(1991)
J. Mol. Biol
, vol.222
, pp. 581-597
-
-
Marks, J.D.1
Hoogenboom, H.R.2
Bonnert, T.P.3
McCafferty, J.4
Griffith, D.5
Winter, G.6
-
19
-
-
0025226085
-
Phage antibodies: Filamentous phage displaying antibody variable domains
-
MCCAFFERTY, J., GRIFFITHS, A.D., WINTER, G. & CHISWELL, D.J. (1990). Phage antibodies: filamentous phage displaying antibody variable domains. Nature, 348, 552-554.
-
(1990)
Nature
, vol.348
, pp. 552-554
-
-
McCafferty, J.1
Griffiths, A.D.2
Winter, G.3
Chiswell, D.J.4
-
20
-
-
0024426529
-
Experience with the use of high dose interleukin-2 in the treatment of 652 cancer patients
-
ROSENBERG, S.A., LOTZE, M.T., YANG, J A., AEBERSOLD, P.M., LINEHAN, W.M., SEIPP, C.A. & WHITE, D.E. (1989). Experience with the use of high dose interleukin-2 in the treatment of 652 cancer patients. Ann. Surg., 210, 474-485.
-
(1989)
Ann. Surg
, vol.210
, pp. 474-485
-
-
Rosenberg, S.A.1
Lotze, M.T.2
Yang, J.A.3
Aebersold, P.M.4
Linehan, W.M.5
Seipp, C.A.6
White, D.E.7
-
21
-
-
84966155416
-
-
SAVAGE, P.M., BEYNON, H.C., SO, A., WALPORT, M.J. & EPENETOS, A.A. (1993). The single chain antibody interleukin-2 fusion protein mimics the effects of rIL-2 on endothelial cell permeability (submitted).
-
(1993)
The Single Chain Antibody Interleukin-2 Fusion Protein Mimics the Effects of Ril-2 on Endothelial Cell Permeability (Submitted)
-
-
Savage, P.M.1
Beynon, H.C.2
So, A.3
Walport, M.J.4
Epenetos, A.A.5
-
22
-
-
0020594115
-
Production and characterization of monoclonal antibodies to human interleukin-2: Strategy and tactics
-
SMITH, K.A., FAVATA, M.F. & OROSZLAN, S. (1983). Production and characterization of monoclonal antibodies to human interleukin-2: strategy and tactics. J. Immunol., 131, 1808-1815.
-
(1983)
J. Immunol
, vol.131
, pp. 1808-1815
-
-
Smith, K.A.1
Favata, M.F.2
Oroszlan, S.3
-
23
-
-
0024673026
-
Characterization of degp: A gene required for proteolysis in the cell envelope and essential for growth of escherichia coli at high temperature
-
STAUCH, K.L., JOHNSON, K. & BECKWITH, J. (1989). Characterization of degP: a gene required for proteolysis in the cell envelope and essential for growth of Escherichia coli at high temperature. J. Bact., 171, 2689-2696.
-
(1989)
J. Bact
, vol.171
, pp. 2689-2696
-
-
Stauch, K.L.1
Johnson, K.2
Beckwith, J.3
-
24
-
-
0009482260
-
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
-
TOWBIN, H., STAEHELIN, T. & GORDON, J. (1979). Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl Acad. Sci. USA, 76, 4350-4354.
-
(1979)
Proc. Natl Acad. Sci. USA
, vol.76
, pp. 4350-4354
-
-
Towbin, H.1
Staehelin, T.2
Gordon, J.3
-
25
-
-
0024461313
-
Binding activities of a repertoire of single immunoglobulin variable domains secreted from escherichia coli
-
WARD, E.S., GUSSOW, D., GRIFFITHS, A.D., JONES, P.T. & WINTER, G. (1989). Binding activities of a repertoire of single immunoglobulin variable domains secreted from Escherichia coli. Nature, 341, 544-546.
-
(1989)
Nature
, vol.341
, pp. 544-546
-
-
Ward, E.S.1
Gussow, D.2
Griffiths, A.D.3
Jones, P.T.4
Winter, G.5
-
26
-
-
0023529699
-
Diptheria toxin receptor binding domain substitution with interleukin-2: Genetic construction and properties of a diptheria toxin-related interleukin-2 fusion protein
-
WILLIAMS, D.P., PARKER, K., BACHA, P., BISHAI, W., BOROWSKI, M., GENBAUFFE, F., STROM, T.B. & MURPHY, J.R. (1987). Diptheria toxin receptor binding domain substitution with interleukin-2: genetic construction and properties of a diptheria toxin-related interleukin-2 fusion protein. Prot. Engin., 1, 493-498.
-
(1987)
Prot. Engin
, vol.1
, pp. 493-498
-
-
Williams, D.P.1
Parker, K.2
Bacha, P.3
Bishai, W.4
Borowski, M.5
Genbauffe, F.6
Strom, T.B.7
Murphy, J.R.8
-
27
-
-
0026684815
-
Rapid tumour penetration of a single-chain fv and comparison with other immunoglobulin forms
-
YOKOTA, T., MILENIC, D.E., WHITLOW, M. & SCHLOM, J. (1992). Rapid tumour penetration of a single-chain Fv and comparison with other immunoglobulin forms. Cancer Res., 52, 3402-3408.
-
(1992)
Cancer Res
, vol.52
, pp. 3402-3408
-
-
Yokota, T.1
Milenic, D.E.2
Whitlow, M.3
Schlom, J.4
|