Inhibitory effect of grapefruit juice and its bitter principal, naringenin, on CYP1A2 dependent metabolism of caffeine in man.

British Journal of Clinical Pharmacology

Volumn 35, Issue 4, 1993, Pages 431-436

  Fuhr, U ^a   Klittich, K ^a   Staib, AH ^a  

^a UNIVERSITY HOSPITAL FRANKFURT   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CAFFEINE; CYTOCHROME P450; NARINGENIN;

ARTICLE; DRUG CLEARANCE; DRUG HALF LIFE; DRUG METABOLISM; ENZYME ACTIVITY; FOOD DRUG INTERACTION; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL;

ADULT; BEVERAGES; CAFFEINE; CITRUS; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 ENZYME SYSTEM; DRUG INTERACTIONS; FEMALE; FLAVONES; HUMAN; MALE; MIDDLE AGE; MOUTH MUCOSA; OXIDOREDUCTASES; SALIVA; SMOKING; SUBSTRATE SPECIFICITY;

EID: 0027510377     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/j.1365-2125.1993.tb04162.x     Document Type: Article

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