Structural abnormalities in deficit and nondeficit schizophrenia

American Journal of Psychiatry

Volumn 150, Issue 1, 1993, Pages 59-65

  Buchanan, Robert W ^a,b   Breier, Alan ^a   Kirkpatrick, Brian ^a   Elkashef, Ahmed ^a   Munson, Robert C ^a   Gellad, Fouad ^a   Carpenter Jr , William T ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b MARYLAND PSYCHIATRIC RESEARCH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CLINICAL ARTICLE; COMPARATIVE STUDY; COMPUTER ASSISTED TOMOGRAPHY; DISEASE ASSOCIATION; FEMALE; FUNCTIONAL ANATOMY; HUMAN; HYPOTHESIS; IMAGE ANALYSIS; MALE; MORPHOMETRICS; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; SCHIZOPHRENIA;

FRONTAL LOBE; HUMAN; MAGNETIC RESONANCE IMAGING; MODELS, NEUROLOGICAL; PARIETAL LOBE; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY; SUPPORT, U.S. GOV'T, P.H.S.; THALAMUS;

EID: 0027509880     PISSN: 0002953X     EISSN: None     Source Type: Journal    
DOI: 10.1176/ajp.150.1.59     Document Type: Article

References (49)

1. Marks RC, Luchins DJ: Relationship between brain imaging findings in schizophrenia and psychopathology, in Schizophrenia: Positive and Negative Symptoms and Syndromes: Modern Problems in Pharmacopsychiatry, vol 24. Edited by Andreasen NC. Basel, Karger, 1990
2. Andreasen NC, Olsen SA, Dennert JW, Smith MR: Ventricular enlargement in schizophrenia: relationship to positive and negative symptoms. Am J Psychiatry 1982; 139:297-302
3. Pearlson GD, Garbacz DJ, Breakey WR, Ahn HS, DePaulo JR: Lateral ventricular enlargement associated with persistent unemployment and negative symptoms in both schizophrenia and bipolar disorder. Psychiatry Res 1984; 12:1-9
4. Kolakowska T, Williams AO, Ardern M, Reveley MA, Jambor K, Gelder MG, Mandelbrote BM: Schizophrenia with good and poor outcome, I: early clinical features, response to neuroleptics and signs of organic dysfunction. Br J Psychiatry 1985; 146:229-239
5. Kemali D, Maj M, Galderisi S: Clinical, biological, and neuropsychological features associated with lateral ventricular enlargement in DSM-III schizophrenic disorder. Psychiatry Res 1987; 21:137-149
6. van Kammen DP, van Kammen WB, Peters J, Goetz K, Neylan T: Decreased slow-wave sleep and enlarged ventricles in schizophrenia. Neuropsychopharmacology 1988; 1:265-271
7. Andreasen NC, Ehrhardt JC, Swayze VW II, Alliger RJ, Yuh WT, Cohen G, Ziebell S: Magnetic resonance imaging of the brain in schizophrenia: the pathophysiologic significance of structural abnormalities. Arch Gen Psychiatry 1990; 47:35-44
8. Luchins D, Lewine R, Meltzer H: Lateral ventricular size, psychopathology and medication response in the psychoses. Biol Psychiatry 1984; 19:29-44
9. Owens DG, Johnstone EC, Crow TJ, Frith CD, Jagoe JR, Kreel L: Lateral ventricular size in schizophrenia: relationship to the disease process and its clinical manifestations. Psychol Med 1985; 15:27-41
10. Losonczy MF, Song IS, Mohs RC, Small NA, Davidson M, Johns CA, Davis KL: Correlates of lateral ventricular size in chronic schizophrenia, I: behavioral and treatment response measures. Am J Psychiatry 1986; 143:976-981
11. Pandurangi AK, Dewan MJ, Boucher M, Levy B, Ramachandran T, Bartell K, Bick PA, Phelps BH, Major L: A comprehensive study of chronic schizophrenic patients, II: biological, neuropsychological, and clinical correlates of CT abnormality. Acta Psychiatr Scand 1986; 73:161-171
12. Ota T, Maeshiro H, Ishido H, Shimizu Y, Uchida R, Toyoshima R, Ohshima H, Takazawa A, Motomura H, Noguchi T: Treatment-resistant chronic psychopathology and CT scans in schizophrenia. Acta Psychiatr Scand 1987; 75:415-427
13. Keilp JG, Sweeney JA, Jacobsen P, Solomon C, St Louis L, Deck M, Frances A, Mann JJ: Cognitive impairment in schizophrenia: specific relations to ventricular size and negative symptomatology. Biol Psychiatry 1988; 24:47-55
14. Pfefferbaum A, Zipursky RB, Lim KO, Zatz LM, Stahl SM, Jernigan TL: Computed tomographic evidence for generalized sulcal and ventricular enlargement in schizophrenia. Arch Gen Psychiatry 1988; 45:633-640
15. Andreasen NC, Swayze VW II, Flaum M, Yates WR, Arndt S, McChesney C: Ventricular enlargement in schizophrenia evalu ated with computed tomographic scanning: effects of gender, age, and stage of illness. Arch Gen Psychiatry 1990; 47:1008-1015
16. Bishop RJ, Golden CJ, MacInnes WD, Chu CC, Ruedrich SL, Wilson J: The BPRS in assessing symptom correlates of cerebral ventricular enlargement in acute and chronic schizophrenia. Psychiatry Res 1983; 9:225-231
17. Levin S: Frontal lobe dysfunctions in schizophrenia, II: impairments of psychological and brain functions. J Psychiatr Res 1984; 18:57-72
18. Weinberger DR: Implications of normal brain development for the pathogenesis of schizophrenia. Arch Gen Psychiatry 1987; 44:660-669
19. Kirkpatrick B, Buchanan RW: The neural basis of the deficit syndrome of schizophrenia. J Nerv Ment Dis 1990; 178:545-555
20. Andreasen N, Nasrallah HA, Dunn V, Olson SC, Grove WM, Ehrhardt JC, Coffman JA, Crossett JH: Structural abnormalities in the frontal system in schizophrenia: a magnetic resonance imaging study. Arch Gen Psychiatry 1986; 43:136-144
21. Besson JA, Corrigan FM, Cherryman GR, Smith FW: Nuclear magnetic resonance brain imaging in chronic schizophrenia. Br J Psychiatry 1987; 150:161-163
22. Andreasen NC: Positive and negative symptoms: historical and conceptual aspects, in Schizophrenia: Positive and Negative Symptoms and Syndromes: Modern Problems in Pharmacopsychiatry, vol 24. Edited by Andreasen NC. Basel, Karger, 1990
23. McGlashan TH, Fenton WS: The positive-negative distinction in schizophrenia: review of natural history validators. Arch Gen Psychiatry 1992; 49:63-72
24. Carpenter WT Jr, Heinrichs DW, Wagman AMI: Deficit and nondeficit forms of schizophrenia: the concept. Am J Psychiatry 1988; 145:578-583
25. Carpenter WT, Buchanan RW: Domains of psychoparhology relevant to the study of etiology and treatment in schizophrenia, in Schizophrenia: Scientific Progress. Edited by Schulz SC, Tamminga CA. New York, Oxford University Press, 1989
26. Kirkpatrick B, Buchanan RW: Anhedonia and the deficit syndrome of schizophrenia. Psychiatry Res 1989; 31:25-30
27. Thaker G, Kirkpatrick B, Buchanan RW, Ellsberry R, Lahti A, Tamminga C: Oculomotor abnormalities and their clinical correlates in schizophrenia. Psychopharmacol Bull 1989; 25:491-497
28. Buchanan RW, Kirkpatrick B, Tamminga CA: Differential patterns of glucose metabolism in deficit and nondeficit schizophrenia (abstract). Biol Psychiatry 1989; 25(7A):99A-100A
29. Buchanan RW, Kirkpatrick B, Heinrichs DW, Carpenter WT Jr: Clinical correlates of the deficit syndrome of schizophrenia. Am J Psychiatry 1990; 147:290-294
30. Pierrot-Deseilligny C, Rivaud S, Gaymard B, Agid Y: Cortical control of reflexive visually-guided saccades. Brain 1991; 114: 1473-1485
31. Alexander GE, DeLong MR, Strick PL: Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Ann Rev Neurosci 1986; 9:357-381
32. Alexander GE, Crutcher MD: Functional architecture of basal ganglia circuits: neural substrates of parallel processing. Trends Neurosci 1990; 13:266-270
33. Breier A, Buchanan RW, Elkashef A, Munson RC, Kirkpatrick B, Gellad F: Brain morphology and schizophrenia: an MRI study of limbic, prefrontal cortex, and caudate structures. Arch Gen Psychiatry (in press)
34. Kirkpatrick B, Buchanan RW, McKenney PD, Alphs LD, Carpenter WT Jr: The Schedule for the Deficit Syndrome: an instrument for research in schizophrenia. Psychiatry Res 1989; 30: 119-123
35. Spitzer RL, Williams JBW, Gibbon M, First MD: Structured Clinical Interview for DSM-III-R - Patient Version (SCID-P). New York, New York State Psychiatric Institute, Biometrics Research, 1989
36. Loats HL, Holcomb HH: Image analysis, in Medical Radiology Innovations in Diagnostic Radiology. Edited by Anderson JH. Berlin, Springer-Verlag, 1989
37. Jernigan TL, Press GA, Hesselink JR: Methods for measuring brain morphologic features on magnetic resonance images: validation and normal aging. Arch Neurol 1990; 47:27-32
38. Jernigan TL, Archibald SL, Berhow MT, Sowell ER, Foster DS, Hesselink JR: Cerebral structure on MRI, part I: localization of age-related changes. Biol Psychiatry 1991; 29:55-67
39. Matsui T, Hirano A: An Atlas of the Human Brain for Computerized Tomography. New York, Igaku-Shoin Medical Publishers, 1978
40. Schnitzlein HN, Murtagh FR: An Atlas of the Human Brain for Computerized Tomography. Baltimore, Urban & Schwarzenberg, 1985
41. Kelsoe JR Jr, Cadet JL, Pickar D, Weinberger DR: Quantitative neuroanatomy in schizophrenia. Arch Gen Psychiatry 1988; 45: 533-541
42. Suddath RL, Casanova MF, Goldberg TE, Daniel DG, Kelsoe JR Jr, Weinberger DR: Temporal lobe pathology in schizophrenia: a quantitative magnetic resonance imaging study. Am J Psychiatry 1989; 146:464-472
43. Suddath RL, Christison GW, Torrey EF, Casanova MF, Weinberger DR: Anatomical abnormalities in the brains of monozygotic twins discordant for schizophrenia. N Engl J Med 1990; 322:789-794
44. Bogerts B, Ashtari M, Degreef G, Alvir JM, Bilder RM, Lieberman JA: Reduced temporal limbic structure volumes on magnetic resonance images in first episode schizophrenia. Psychiatry Res 1990; 35:1-13
45. DeLisi LE, Hoff AL, Schwartz JE, Shields GW, Halthore SN, Gupta SM, Henn FA, Anand AK: Brain morphology in first-episode schizophrenic-like psychotic patients: a quantitative magnetic resonance imaging study. Biol Psychiatry 1991; 29:159-175; correction, 29:519
46. Jernigan TL, Zisook S, Heaton RK, Moranville JT, Hesselink JR, Braff DL: Magnetic resonance imaging abnormalities in lenticular nuclei and cerebral cortex in schizophrenia. Arch Gen Psychiatry 1991; 48:881-890
47. Ziputsky RB, Lim KO, Sullivan EV, Brown BW, Pfefferbaum A: Widespread cerebral gray matter volume deficits in schizophrenia. Arch Gen Psychiatry 1992; 49:195-205
48. Fuster JM: The Prefrontal Cortex, 2nd ed. New York, Raven Press, 1989
49. Stevens JR: Abnormal reinnervation as a basis for schizophrenia: a hypothesis. Arch Gen Psychiatry 1992; 49:238-243