Acute liver rejection: Evaluation with cell-directed MR contrast agents in a rat transplantation model

Radiology

Volumn 186, Issue 1, 1993, Pages 139-146

  Mühler, Andreas ^a   Freise, Chris E ^a   Kuwatsuru, Ryohei ^a   Rosenau, Werner ^a   Liu, Tao ^a   Mintorovitch, Jan ^a   Clement, Olivier ^a   Vexier, Vladimir ^a   Mahboubi, Soroosh ^a   Lang, Philipp ^a   Roberts, John P ^a   Brasch, Robert C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Contrast media, experimental studies; Gadolinium; Iron; Liver, transplantation, 761.459; Magnetic resonance (MR), contrast enhancement

Indexed keywords

NUCLEAR MAGNETIC RESONANCE IMAGING AGENT; PENTETIC ACID;

ALLOGRAFT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; DRUG UPTAKE; ELECTRON MICROSCOPY; GRAFT REJECTION; HUMAN; ISOGRAFT; LIVER INJURY; MALE; MODEL; NUCLEAR MAGNETIC RESONANCE IMAGING; PHAGOCYTOSIS; PRIORITY JOURNAL; RAT;

ACUTE DISEASE; ANIMAL; CONTRAST MEDIA; GRAFT REJECTION; LIVER; LIVER TRANSPLANTATION; MAGNETIC RESONANCE IMAGING; MALE; ORGANOMETALLIC COMPOUNDS; PENTETIC ACID; RATS; RATS, INBRED LEW; RATS, INBRED STRAINS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TRANSPLANTATION, ISOGENEIC;

EID: 0027492211     PISSN: 00338419     EISSN: None     Source Type: Journal    
DOI: 10.1148/radiology.186.1.8416555     Document Type: Review

References (43)

1. Sibley R, Snover D. The use and interpretation of biopsies in the management of the post transplant patient. In: Cerilli G, ed. Organ transplantation and replacement. Philadelphia: Lippincott, 1988; 406-410.
2. Ascher N, Stock P, Baumgardner G, et al. Infection and rejection of primary hepatic transplant in 93 consecutive patients treated with triple immuno-suppressive therapy. Surg Gynecol Obstet 1988; 167: 474-484.
3. Demetris JD. The pathology of liver transplantation. Prog Liver Dis 1990; 9:687-709.
4. Snover D, Sibley R, Freese D, et al. Orthotopic liver transplantation: a pathological study of 63 serial liver biopsies from 17 patients with special reference to the diagnostic features and natural history of rejection. Hepatology 1984; 4:1212-1222.
5. Und G, Letourneau J, Day D, et al. MRI in organ transplantation. Radiol Clin North Am 1987; 25:281-288.
6. Gassel HJ, Engemann R, Thiede A, Hamelmann H. Replacement of donor Kupffer cells by recipient cells after orthotopic liver transplantation. Transplant Proc 1987; 19: 351-353.
7. Icard P, Sawyer G, Houssin D, Fabre J. Marked differences between orthotopic and heterotopic auxiliary liver allografts in the induction of class IIMHC antigens on hepatocytes (abstr). Transplant Proc 1990; 22:1935.
8. Steinhoff G, Wonigkeit K, Sorg C, Behrend M, Mues B, Pichlmayr R. Patterns of macrophage immigration and differentiation in human liver grafts. Transplant Proc 1989; 21:398-400.
9. Inagaki M, Sakagami K, Orita K. Immunological role of hepatic sinusoidal lining cells in swine liver transplantation. Transplant Proc 1990; 22:1936-1940.
10. Hawkins R, Hall T, Gambhir S, et al. Radionuclide evaluation of liver transplants. Semin Nucl Med 1988; 18:199-212.
11. Weinmann HJ, Schuhmann-Giampieri G, Schmitt-Willich H, Vogler H, Frenzel T, Gries H. A new lipophilic gadolinium chelate as a tissue-specific contrast medium for MRI. Magn Reson Med 1991; 22:233-237.
12. Schuhmann-Giampieri G, Schmitt-Willich H, Press WR, Negishi C, Weinmann HJ, Speck U. Preclinical evaluation of Gd-EOB-DTPA as a contrast agent in MR imaging of the hepatobiliary system. Radiology 1992; 183:59-64.
13. Weissleder R, Stark DD, Engelstad BL, et al. Superparamagnetic iron oxide: pharmacokinetics and toxicity. AJR 1989; 152:167-173.
14. Kamada N, Calne R. Orthotopic liver transplantation in the rat. Transplantation 1979; 28:47-50.
15. Kamada N, Calne R. A surgical experience with five hundred thirty liver transplants in the rat. Surgery 1983; 93:64-69.
16. Kamada N, Davies HS, Wight D, Culank L, Roser B. Liver transplantation in the rat: biochemical and histological evidence of complete tolerance induction in non-rejector strains. Transplantation 1983; 35:304-311.
17. Clement O, Mühler A, Vexler VS, et al. Evaluation of radiation-induced liver injury with MR imaging: comparison of hepatocellular and reticuloendothelial contrast agents. Radiology 1992; 185:163-168.
18. Moseley RH. Mechanism of bile formation and cholestasis: clinical significance of recent experimental work. Am J Gastroenterol 1986; 81:731-735.
19. Fritzberg AR. Animal models in the study of hepatobiliary radiotracers. In: Lambrecht RM, Eckelman WC, eds. Animal models in radiotracer design. New York: Springer-Verlag, 1983; 179-209.
20. Mühler A, Clement O, Vexler V, Berthezène Y, Rosenau W, Brasch RC. Hepatobiliary enhancement with Gd-EOB-DTPA: comparison of spin-echo and STIR imaging for detection of experimental liver metastases. Radiology 1992; 184:207-213.
21. Liu T, Friese C, Ascher N, Roberts JP. A modified vascular "sleeve" anastomosis for rearterialization in orthotopic liver transplantation in rats. Transplantation 1992; 54:179-180.
22. Loken M, Ascher N, Boudrea R, Najarian J. Scintigraphic evaluation of liver transplant function. J Nucl Med 1986; 27:451-459.
23. Letourneau J. Radiology of hepatic transplantation. Crit Rev Diagn Imaging 1990; 30:281-315.
24. Lang P, Mauz M, Steffen R, et al. MR imaging in liver transplantation: focal abnormalities of the liver allograft (abstr). In: Book of abstracts: Society of Magnetic Resonance in Medicine 1990. Berkeley, Calif: Society of Magnetic Resonance in Medicine, 1990; 788.
25. Engemann R, Ulrichs K, Thiede A, Müller-Ruchholtz W, Hamelman H. Induction of liver graft tolerance in a primarily nontolerant rat strain combination with temporary treatment of cyclosporine. Transplant Proc 1983; 15:2986-2991.
26. Howden B, Jablonski P, Grossman H, Marshall V. The importance of the hepatic artery in rat liver transplantation. Transplantation 1989; 47:428-431.
27. Pirsch J, Kalayoglu M, Hafez G, D'Alessandro A, Sollinger H, Belzer F. Evidence that the vanishing bile duct syndrome is vanishing. Transplantation 1990; 49:1015-1017.
28. Steinhoff G, Wenigkeit K, Pichlmayr R. Analysis of sequential changes in major histocompatibility complex expression in human liver grafts after transplantation. Transplantation 1988; 45:394-401.
29. Steinhoff G, Wenigkeit K, Pichlmayr R. Modified donor MHC-expression and replacement of Kupffer cells in human liver grafts (abstr). J Hepatol 1987; 5(suppl):65.
30. Caldwell-Kenkel J, Currin R, Tanaka Y, Thurman R, Lemasters J. Reperfusion injury to endothelial cells following cold ischemic storage of rat livers. Hepatology 1989; 10:292-299.
31. Groth C, Porter K, Otte J, et al. Studies of blood flow and ultrasrrucrural changes in rejecting and nonrejecting canine orthotopic liver homografts. Surgery 1968; 63: 658-668.
32. White R, Zajko A, Demetris A, Bron K, Dekker A, Starzl T. Liver transplant rejection: angiographic findings in 35 patients. AJR 1987; 148:1095-1098.
33. Marder D, DeMarino G, Sumkin J, Sheahan D. Liver transplant rejection: value of the resistive index in Doppler US of hepatic arteries. Radiology 1989; 173:127-129.
34. Bauman J, Campbell W, Demetris A, Zajko A. Intrahepatic cholangiographic abnormalities in liver transplants: correlation with biopsy evidence of rejection and other disorders. AJR 1989; 152:275-279.
35. Woodle E, Vera D, Stadalnik RC, Ward R. Tc-NGA imaging in liver transplantation: preclinical studies. Surgery 1987; 102:55-62.
36. Callery M, Kamei T, Flye M. Kupffer cell blockade inhibits induction of tolerance by the portal venous route. Transplantation 1989; 47:1092-1094.
37. Rossleigh M, McCaughan G, Gallagher N, et al. The role of nuclear medicine in liver transplantation. Med J Aust 1988; 148:561-563.
38. Woodle E, Ward R, Stadalnik R, Vera D. Tc-NGA imaging in liver transplantation: preliminary clinical experience. Surgery 1989; 105:401-407.
39. Kuni C, Engeler C, Nakleh R, duCret R, Boudreau R. Correlation of technetium-99m-DISIDA hepatobiliary studies in liver transplant patients. J Nucl Med 1991; 32: 1545-1547.
40. Letourneau J, Castaneda-Zuniga W. The role of radiology in the diagnosis and treatment of biliary complications after liver transplantation. Cardiovasc Intervent Radiol 1990; 13:278-282.
41. Evans R, Raby N, O'Grady J, et al. Biliary complications following orthotopic liver transplantation. Clin Radiol 1990; 41:190-194.
42. Scott-Smith W, Raftery A, Wraight W, Caline R. Tc-99m labeled HIDA imaging in suspected biliary leaks after liver transplantation. Clin Nucl Med 1982; 10:478-479.
43. Brown R, Memsic L, Busuttil R, et al. Accurate demonstration of hepatic infarction in liver transplant recipients. J Nucl Med 1986; 27:1428-1431.