Chemical and biological evidence links microcystins to salmon 'netpen liver disease'

Toxicon

Volumn 31, Issue 10, 1993, Pages 1315-1323

  Andersen, Raymond J ^a   Luu, Hue A ^b   Chen, Dawn Z X ^b   Holmes, Charles F B ^b   Kent, Michael L ^c   Le Blanc, Mike ^a   Taylor, F J R 'Max' ^a   Williams, David E ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

^c PACIFIC BIOLOGICAL STATION   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CYANOGINOSIN LR; ENZYME INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; LIVER DISEASE; LIVER NECROSIS; NONHUMAN; SALMON;

ANIMAL; AQUACULTURE; CHROMATOGRAPHY, LIQUID; FISH DISEASES; LIVER DISEASES; MARINE TOXINS; PEPTIDES, CYCLIC; PHOSPHOPROTEIN PHOSPHATASE; SALMON; SUPPORT, NON-U.S. GOV'T;

ANIMALIA; SALMO SALAR;

EID: 0027491267     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/0041-0101(93)90404-7     Document Type: Article

References (16)

1. Toxins of freshwater algae
2. Identification of protein phosphatase inhibitors of the microcystin class in the marine environment
3. Motuporin, a potent protein phosphatase inhibitor isolated from the Papua New Guinea sponge Theonella swinhoei gray
4. Liver and kidney pathology in rainbow trout (Salmo gairdneri) exposed to dietary pyrrolizidine (Senecio) alkaloids
5. Liver structural alterations accompanying chronic toxicity in fishes: Potential biomarkers of exposure
6. Histopathological biomarkers
7. Liquid chromatography-linked protein phosphatase bioassay; a highly sensitive marine bioscreen for okadaic acid and related diarrhetic shellfish toxins
8. Netpen liver disease (NLD) of salmonid fishes reared in sea water; species susceptibility recovery and probable cause
9. Suspected toxicopathic hepatic necrosis and megalocytosis in pen-reared Atlantic salmon Salmo salar in Puget Sound Washington USA
10. Quantification of diarrhetic shellfish toxins and identification of novel protein phosphatase inhibitors in marine phytoplankton and mussels
11. Pathologic anatomy and patterns of occurrence of hepatic neoplasms, putative preneoplastic lesions, and other idiopathic hepatic conditions in English sole (Parophrys vetulus) from Puget Sound, Washington
12. The toxicity of the cyanobacterium Microcystis aeruginosa to rainbow trout, Salmo gairdneri Richardson
13. Histopathological effects of microcystin-LR a cyclic peptide toxin from the cyanobacterium (blue-green alga) microcystis aeruginosa on common carp (Cyprinus carpio L)
14. Degeneration and regeneration of liver parenchyma accompanying hepatogenesis