Angiogenesis Inhibitor TNP-470 (AGM-1470) Potently Inhibits the Tumor Growth of Hormone-independent Human Breast and Prostate Carcinoma Cell Lines

Cancer Research

Volumn 53, Issue 21, 1993, Pages 5233-5236

  Yamaoka, Masuo ^a   Yamamoto, Toshihiro ^a   Ikeyama, Shuichi ^a   Sudo, Katsuichi ^a   Fujita, Takeshi ^a  

^a TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; DOXORUBICIN; FLUOROURACIL; FUMAGILLOL CHLOROACETYLCARBAMATE;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; COLON CANCER; CONTROLLED STUDY; FEMALE; HORMONAL REGULATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE CARCINOMA; TUMOR GROWTH; TUMOR VOLUME; XENOGRAFT;

ANIMAL; ANTIBIOTICS, ANTINEOPLASTIC; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BREAST NEOPLASMS; CELL DIVISION; CELL LINE; CELL SURVIVAL; CISPLATIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; DRUG SYNERGISM; FLUOROURACIL; HUMAN; MALE; MICE; NEOVASCULARIZATION, PATHOLOGIC; PROSTATIC NEOPLASMS; SESQUITERPENES; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED;

EID: 0027487871     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Stearns, M. E. and McGarvey, T. Biology of disease prostate cancer: therapeutic, diagnostic, and basic studies. Lab. Invest., 67: 540-552, 1992.
2. Tannock, I. F. Is there evidence that chemotherapy is of benefit to patients with carcinoma of the prostate? J. Clin. Oncol., 3: 1013-1021, 1985.
3. Nakamoto, T., Chang, C., Li, A. and Chodak, G. W. Basic fibroblast growth factor in human prostate cancer cells. Cancer Res., 52: 571-577, 1992.
4. Crabb, J. W., Armes, L. G., Johnson, C. M. and McKeehan, W. L. Characterization of multiple forms of prostatropin (prostate epithelial cell growth factor) from bovine brain. Biochem. Biophys. Res. Commun., 136: 1155-1161, 1986.
5. Esch, F., Baird, A., Ling, N., Ueno, N., Hill, F., Denoroy, L., Klepper, R., Gospodarowicz, D., Böhlen, P. and Guillemin, R. Primary structure of bovine pituitary basic fibroblast growth factor (FGF) and comparison with the amino-terminal sequence of bovine brain acidic FGF. Proc. Natl. Acad. Sci. USA, 82: 6507-6511, 1985.
6. Shing, Y., Folkman, J., Sullivan, R., Butterfield, C., Murray, J. and Klagsbrun, M. Heparin affinity: purification of a tumor-derived capillary endothelial cell growth factor. Science (Washington DC), 223: 1296-1299, 1984.
7. Shing, Y., Folkman, J., Haudenschild, C., Lund, D., Crum, R. and Klagsbrun, M. Angiogenesis is stimulated by a tumor-derived endothelial cell growth factor. J. Cell. Biochem., 29: 275-287, 1985.
8. Wellstein, A., Fang, W., Khatri, A., Lu, Y., Swain, S. S., Dickson, R. B., Sasse, J., Riegel, A. T. and Lippman, M. E. A heparin-binding growth factor secreted from breast cancer cells homologous to a developmentally regulated cytokine. J. Biol. Chem., 267: 2582-2587, 1992
9. Ingber, D., Fujita, T., Kishimoto, S., Sudo, K., Kanamaru, T., Brem, H. and Folkman, J. Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth. Nature (Lond.) 348: 555-557, 1990.
10. Kusaka, M., Sudo, K., Fujita, T., Marui, S., Itoh, F., Ingber, D. and Folkman, J. Potent anti-angiogenic action of AGM-1470: comparison to the fumagillin parent. Biochem. Biophys. Res. Commun., 174: 1070-1076, 1991.
11. Geran, R. I., Greenberg, N. H., MacDonald, M. M., Schumacher, A. M. and Abbott, B. J. Protocols for screening chemical agents and natural products against animal tumors and other biological systems. Cancer Chemother. Rep., 3: 1-103, 1972.
12. Kaighn, M. E., Lechner, J. F., Narayan, K. S. and Jones, L. W. Prostate carcinoma: tissue culture cell lines. Natl. Cancer Inst. Monogr., 49: 17-21, 1978.
13. Cailleau, R., Young, R., Olivé, M. and Reeves, W. J. Jr. Breast tumor cell lines from pleural effusions. J. Natl. Cancer Inst., 53: 661-674, 1974.
14. Noguchi, P., Wallace, R., Johnson, J., Earley, E. M. O'Brien, S., Ferrone, S. Pelle-grino, M. A., Milstien, J., Needy, C., Browne, W. and Petricciani, J. Characterization of WiDr: a human colon carcinoma cell line. In Vitro, 15: 401-408, 1979.
15. Yamaoka, M., Yamamoto, T., Masaki, T., Ikeyama, S., Sudo, K. and Fujita, T. Inhibition of tumor growth and metastasis of rodent tumors by the angiogenesis inhibitor O-(chloroacetyl-carbamoyl)fumagillol (TNP-470; AGM-1470). Cancer Res., 53: 4262-4267, 1993.
16. Sugita, A., Gottardis, M., Lippman, M., Itoh, C., Ueda, N. and Fukunishi, R. Anti-angiogenic factor in breast cancer. Proc. Jpn. Cancer Assoc. 51st Annual Meeting, p. 306, 1992.
17. Teicher, B. A., Sotomayor, E. A. and Huang, Z. D. Antiangiogenic agents potentiate cytotoxic cancer therapies against primary and metastatic disease. Cancer Res., 52: 6702-6704, 1992.
18. Folkman, J. Anti-angiogenesis: new concept for therapy of solid tumors. Ann. Surg., 175: 409-416, 1972.