Affinity panning of a library of peptides displayed on bacteriophages reveals the binding specificity of BiP

Cell

Volumn 75, Issue 4, 1993, Pages 717-728

  Blond Elguindi, Sylvie ^a,c   Cwirla, Steven E ^b   Dower, William J ^b   Lipshutz, Robert J ^d   Sprang, Stephen R ^a,c   Sambrook, Joseph F ^a   Gething, Mary Jane H ^a,c  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c AFFYMAX RESEARCH INSTITUTE   (United States)

^d Daniel H Wagner Associates   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

UNIDENTIFIED BACTERIOPHAGE;

ADENOSINE TRIPHOSPHATASE;

AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIOPHAGE; BINDING AFFINITY; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; MEMBRANE TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN TRANSPORT;

ADENOSINETRIPHOSPHATASE; AMINO ACID SEQUENCE; BASE SEQUENCE; CHAPERONINS; CONSENSUS SEQUENCE; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; FUNGAL PROTEINS; GENE LIBRARY; HEAT-SHOCK PROTEINS; IN VITRO; INOVIRUS; MOLECULAR SEQUENCE DATA; OLIGODEOXYRIBONUCLEOTIDES; OLIGOPEPTIDES; PROTEIN BINDING; PROTEINS; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0027484417     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0092-8674(93)90492-9     Document Type: Article

References (34)

1. Peptide-dependent stimulation of the ATPase activity of the molecular chaperone BiP is the result of conversion of oligomers to active monomers
2. Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1
3. Peptides on phage: a vast library of peptides for identifying ligands
4. Random peptide libraries: a source of specific protein binding molecules
5. Phage power
6. Which came first, MHC class I or class II?
7. Peptide binding and release by proteins implicated as catalysts of protein assembly
8. Peptide-binding specificity of the molecular chaperone BiP
9. Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb
10. Protein folding in the cell
11. Promiscuous and allele-specific anchors in HLA-DR-binding peptides
12. Identification of immunoglobulin heavy chain binding protein as glucose regulated protein 78 on the basis of amino acid sequence immunological crossreactivity and functional activity
13. A simple method for displaying the hydropathic character of a protein
14. Different conformations for the same polypeptide bound to chaperones DnaK and GroEL
15. Successive action of DnaK, DnaJ, and GroEL along the pathway of chaperone-mediated protein folding
16. The three-dimensional structure of HLA-B27 at 2.1 Å resolution suggests a general mechanism for tight peptide binding to MHC
17. Emerging principles for the recognition of peptide antigens by MHC class I molecules
18. An hsp70-like protein in the ER: identity with the 78 kd glucose-regulated protein and immunoglobulin heavy chain binding protein
19. Binding protein BiP is required for translocation of secretory proteins into the endoplasmic reticulum in Saccharomyces cerevisiae
20. Isolation and identification of a polypeptide in the Hsp 70 family that binds substance P
21. Antibody-selectable filamentous fd phage vectors: affinity purification of target genes
22. Peptides naturally presented by MHC class I molecules
23. A hypothetical model for the peptide binding domain of hsp70 based on the peptide binding domain of HLA
24. Sec61p and BiP directly facilitate polypeptide translocation into the ER
25. DNA sequencing with chain-terminating inhibitors
26. Refined structure of the human histocompatibility antigen HLA-A2 at 2.6 Å resolution
27. Targeting and assembly of an oligomeric bacterial enterotoxoid in the endoplasmic reticulum of Saccharomyces cerevisiae
28. Discovering peptide ligands using epitope libraries
29. Searching for peptide ligands with an epitope library
30. Surface presentation of protein epitopes using bacteriophage expression systems
31. The classification of amino acid conservation
32. Loss of BiP/GRP78 function blocks translocation of secretory proteins in yeast
33. Patterns of amino acids near signal-sequence cleavage sites