Fas transduces activation signals in normal human t lymphocytes

Journal of Experimental Medicine

Volumn 178, Issue 6, 1993, Pages 2231-2235

  Alderson, Mark R ^a   Armitage, Richard J ^a   Maraskovsky, Eugene ^a   Tough, Teresa W ^a   Roux, Eileen ^c   Schooley, Ken ^c   Ramsdell, Fred ^b   Lynch, David H ^c  

^a Departments of Cellular Immunology ^*  (United States)

^b Departments of Immunology ^*  (United States)

^c AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE PROTEIN; MONOCLONAL ANTIBODY; NERVE GROWTH FACTOR; NERVE GROWTH FACTOR RECEPTOR; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL DEATH; CELL TRANSFORMATION; CONTROLLED STUDY; ETIOLOGY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

ANTIBODIES, MONOCLONAL; ANTIGENS, CD95; ANTIGENS, SURFACE; HUMAN; LYMPHOCYTE ACTIVATION; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 0027484072     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.178.6.2231     Document Type: Article

References (25)

1. Yonehara, S., A. Ishii, and M. Yonehara. 1989. A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor. J. Exp Med. 169:1747.
2. Trauth, B.C., C. Klas, A.M.J. Peters, S. Matzku, P. Moller, W. Falk, K.-M. Debatin, and P.H. Krammer. 1989. Monoclonal antibody-mediated regression by induction of apoptosis. Science (Wash. DC). 245:301.
3. Itoh, N., S. Yonehara, A. Ishii, M. Yonehara, S.-I. Mizushima, M. Sameshima, A. Hase, Y. Seto, and S. Nagata. 1991. The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis. Cell. 66:233.
4. Johnson, D., A. Lanahan, C.R. Buck, A. Sehgal, C. Morgan, E. Mercer, M. Bothwell, and M. Chao. 1986. Expression and structure of the human NGF receptor. Cell. 47:545.
5. Loetscher, H., Y.-C. Pan, H.-W. Lahm, R. Gentz, M. Brock-haus, H. Tabuchi, and W. Lesslauer. 1990. Molecular cloning and expression of the human 55 kD tumor necrosis factor receptor. Cell. 61:351.
6. Schall, T.J., M. Lewis, K.J. Holler, A. Lee, G.C. Rice, G.H.W. Wong, T. Gatanaga, G.A. Granger, R. Lentz, H. Raab, et al. 1990. Molecular cloning and expression of a receptor for human tumor necrosis factor. Cell. 61:361.
7. Smith, C.A., T. Davis, D. Anderson, L. Slolam, M.P. Beckmann, R. Jerzy, S.K. Dower, D. Cosman, and R.G. Goodwin. 1990. A receptor for tumor necrosis factor defines an unusual family of cellular and viral proteins. Science (Wash. DC). 248: 1019.
8. Camerini, D., G. Walz, W.A.M. Loenen, J. Borst, and B. Seed. 1991. The T cell activation antigen CD27 is a member of the NGF/TNF receptor gene family. J. Immunol. 147:3165.
9. Durkop, H., U. Latza, M. Hummel, F. Eitelbach, B. Seed, and H. Stein. 1992. Molecular cloning and expression of a new member of the nerve growth factor receptor family that is characteristic for Hodgkin’s disease. Cell. 68:421.
10. Stamenkovic, I., E.A. Clark, and B. Seed. 1989. A B-lympho-cyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas. EMBO (Eur. Mol. Biol. Organ.) J. 8:1403.
11. Kwon, B.S., and S.M. Weissman. 1989. cDNA sequences of two inducible T-cell genes. Proc Natl. Acad. Sci. USA. 86:1963.
12. Mallet, S., S. Fossum, and A.N. Barclay. 1990. Characterization of the MRC 0X40 antigen of activated CD4 positive T lymphocytes: a molecule related to nerve growth factor receptor. EMBO (Eur. Mol. Biol. Organ.) J. 9:1063.
13. Smith, C.A., T. Davis, J.M. Wignall, W.S. Din, T. Farrah, C. Upton, G. McFadden, and R.G. Goodwin. 1991. T2 open reading frame from the shope fibroma virus encodes a soluble form of the TNF receptor. Biochem. Biophys. Res. Commun. 176:335.
14. Watanabe-Fukunaga, R., C.I. Brannan, N.G. Copeland, N.A. Jenkins, and S. Nagata. 1992. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature (Land.). 356:314.
15. Gillis, S., M.M. Ferm, W. Ou, and K.A. Smith. 1978. T cell growth factor: parameters of production and a quantitative microassay for activity. J. Immunol 120:2027.
16. Alderson, M.R., T.W. Tough, S.F. Ziegler, and K.H. Grabstein. 1991. Interleukin 7 induces cytokine secretion and tumori-cidal activity by human peripheral blood monocytes. J. Exp Med. 173:923.
17. Maraskovsky, E., M.H. Pech, and A. Kelso. 1991. High-frequency activation of single CD4+ and CD8+ T cells to proliferate and secrete cytokines using anti-receptor antibodies and IL-2. Int. Immunol. 3:255.
18. Maraskovsky, E., A.B. Troutt, and A. Kelso. 1992. Coengagement of CD3 with LFA-1 or ICAM-1 adhesion molecules enhances the frequency of activation of single murine CD4+ and CD8+ T cells and induces synthesis of IL-3 and IFN-7 but not IL-4 or IL-6. Int. Immunol. 4:475.
19. Taswell, C. 1981. Limiting dilution assays for the determination of immunocompetent cell frequencies. J. Immunol. 126: 1614.
20. Miyawaki, T., T. Uehara, R. Nibu, T. Tsuji, A. Yachie, S. Yonehara, and N. Taniguchi. 1992. Differential expression of apoptosis-related Fas antigen on lymphocyte subpopulations in human peripheral blood. J. Immunol. 149:3753.
21. Van Lier, R.A.W., J. Borst, T.M. Vroom, H. Klein, P. Van Mourik, W.P. Zeijlemaker, and C.J.M. Melief. 1987. Tissue distribution and biochemical and functional properties of Tp55 (CD27), a novel T cell differentiation antigen. J. Immunol. 139:1589.
22. 2+-independent T cell-mediated cytotoxicity. J. Exp Med. 177:195.
23. Yokota, S., T.D. Geppert, and P.E. Lipsky. 1988. Enhancement of antigen- and mitogen-induced human T lymphocyte proliferation by tumor necrosis factor-c*. J. Immunol. 140:531.
24. Jelinek, D.F., and P.E. Lipsky. 1987. Enhancement of human B cell proliferation and differentiation by tumor necrosis factor-a and interleukin-1. J. Immunol. 139:2970.
25. Mangan, D.F., G.R. Welch, and S.M. Wahl. 1991. Lipopoly-saccharide, tumor necrosis factor-a, and IL-1/3 prevent programmed cell death (apoptosis) in human peripheral blood monocytes. J. Immunol. 146:1541.