Insulin prophylaxis in individuals at high risk of type 1 diabetes

The Lancet

Volumn 341, Issue 8850, 1993, Pages 927-928

  Keller, R J ^a,b,c,d   Jackson, R A ^a,b,c,d   Eisenbarth, G S ^a,b,c,d   Eisenbarth, G ^a,b,c,d,e  

^a Children's Hospital   (United Kingdom)

^b Joslin Diabetes Center   (United Kingdom)

^c Brigham and Women's Hospital   (United Kingdom)

^d HARVARD MEDICAL SCHOOL   (United States)

^e UNIVERSITY OF COLORADO DENVER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN;

ARTICLE; CHILD; CONTROLLED STUDY; HIGH RISK POPULATION; HUMAN; HUMAN EXPERIMENT; INSULIN DEPENDENT DIABETES MELLITUS; INTRAVENOUS DRUG ADMINISTRATION; PRIORITY JOURNAL; PROPHYLAXIS; RELATIVE; SUBCUTANEOUS DRUG ADMINISTRATION; UNITED STATES;

ADOLESCENT; ADULT; AUTOANTIBODIES; BLOOD GLUCOSE; CHILD; DIABETES MELLITUS, INSULIN-DEPENDENT; FEMALE; FOLLOW-UP STUDIES; GLUCOSE TOLERANCE TEST; HUMAN; INFUSIONS, INTRAVENOUS; INJECTIONS, SUBCUTANEOUS; INSULIN; INSULIN ANTIBODIES; ISLETS OF LANGERHANS; LIFE STYLE; LIFE TABLES; MALE; MASS SCREENING; PEDIGREE; PILOT PROJECTS; PRIMARY PREVENTION; RISK FACTORS; TREATMENT OUTCOME;

EID: 0027480065     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/0140-6736(93)91215-8     Document Type: Article

References (9)

1. Competitive insulin autoantibody assay pospective evaulation of subjects at high risk for development of type I diabetes mellitus
2. Predicting Type I diabetes
3. Dual parameter linear model for prediction of onset of type I diabetes in ICA positive relatives
4. Reduction of diabetes incidence of BB Wister rats by early prophylactic insulin treatment of diabetes-prone animals
5. Insulitis and diabetes in NOD mice reduced by prophylactic insulin therapy
6. A randomized trial of intensive insulin therapy in newly diagnosed insulin-dependent diabetes mellitus
7. Beta cell activity regulates the expression of islet antigenic determinants
8. Interaction of beta-cell activity and IL-1 concentration and exposure time in isolated rat islets of Langerhans
9. Insulin for prophylaxis of insulin-dependent diabetes