Reversal of Rigidity and Improvement in Motor Performance by Subthalamic High‐frequency Stimulation in MPTP‐treated Monkeys

European Journal of Neuroscience

Volumn 5, Issue 4, 1993, Pages 382-389

  Benazzouz, Abdelhamid ^b   Gross, Christian ^b   Féger, Jean ^a   Boraud, Thomas ^b   Bioulac, Bernard ^b  

^a FACULTÉ DES SCIENCES PHARMACEUTIQUES ET BIOLOGIQUES   (France)

^b UNIVERSITÉ DE BORDEAUX   (France)

Author keywords

conditioned movement; high frequency stimulation; MPTP; Parkinson's disease; subthalamic nucleus

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; NEUROTOXIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BASAL GANGLION; BRADYKINESIA; BRAIN DEPTH STIMULATION; DOPAMINERGIC NERVE CELL; ELECTROMYOGRAPHY; INTRAARTERIAL DRUG ADMINISTRATION; MOTOR PERFORMANCE; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; RIGIDITY; SUBSTANTIA NIGRA; SUBTHALAMIC NUCLEUS;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; ANIMAL; BEHAVIOR, ANIMAL; ELECTRIC STIMULATION THERAPY; ELECTROMYOGRAPHY; KINETICS; MACACA MULATTA; MOTOR ACTIVITY; MUSCLE RIGIDITY; MUSCLE TONUS; PARKINSON DISEASE, SECONDARY; SUPPORT, NON-U.S. GOV'T; THALAMUS;

EID: 0027479766     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.1993.tb00505.x     Document Type: Article

References (36)

1. Treating Parkinson's disease with lesion of the subthalamic nucleus
2. The functional anatomy of basal ganglia disorders
3. Functional architecture of basal ganglia circuits: neural substrates of parallel processing
4. Lesion of the subthalamic nucleus for the alleviation of 1‐methyl‐4‐phenyl‐1,2,3,6‐tetra‐hydro‐pyridine (MPTP)‐induced parkinsonism in the primate
5. Chronic Vim‐thalamic stimulation in movement disorders
6. MPTP‐induced hemiparkinsonism in monkeys: behavioral, mechanographic, electromyographic and immunohistochemical studies
7. Reversal of experimental parkinsonism by lesions of the subthalamic nucleus
8. Alleviation of parkinsonism by antagonism of excitatory amino acid transmission in the medial segment of the globus pallidus in rat and primate
9. A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine
10. Experimental hemiballismus in the baboon produced by injection of gamma‐amino‐butyric acid antagonist into the basal ganglia
11. Symptoms and behavioral features induced by 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP) in an old Java monkey [Macaca cynomolgus fascicularis (Raffles)]
12. Primate models of movement disorders of basal ganglia origin
13. Modification of precentral cortex discharge and EMG activity in monkeys with MPTP‐induced lesions of DA nigral neurons
14. Pyramidal tract activity associated with a conditioned hand movement in the monkey
15. Stereotaxic technique for stimulation and recording in nonanesthetized monkeys: application to the determination of connections between caudate nucleus and substantia nigra
16. The subthalamic nucleus: new data and new questions
17. Injection of excitatory amino acid antagonists into the pallidal segment of the MPTP‐treated primate reverses motor symptoms of parkinsonism
18. Electrophysiological demonstration of an excitatory subthalamo‐nigral pathway in the rat
19. Experimental hemiballism in the monkey produced by unilateral kainic acid lesion in corpus Luysii
20. Brain neurotransmitter changes in Parkinson's disease
21. Anatomy and physiology of the subthalamic nucleus: a driving force of the basal ganglia
22. Treatment and prognosis of hemiballismus
23. Selective nigral toxicity after systemic administration of 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP) in the squirrel monkey
24. Altered tonic activity of neurons in the globus pallidus and subthalamic nucleus in the primate MPTP model of Parkinsonism
25. Neural mechanisms underlying parkinsonian symptoms based upon regional uptake of 2‐deoxyglucose in monkeys exposed to 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP)
26. Intracellular study of rat entopeduncular nucleus neurons in an in vitro slice preparation: response to subthalamic stimulation
27. Stereotaxic VIM thalamotomy for treatment of tremor
28. Physiological study of the presumed ventralis intermedius neurons in the human thalamus
29. Organisation of efferent projections of the subthalamic nucleus in the squirrel monkey as revealed by retrograde labelling methods
30. Excitatory influence of rat subthalamic nucleus to substantia nigra pars reticulata and the pallidal complex: electrophysiological data
31. Mise en évidence d'un effet excitateur des efférences subthalamo‐nigrales et subthalamo‐pallidales chez le rat
32. Deficits in behavioral initiation and execution processes in monkeys with 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine‐induced parkinsonism
33. Parkinson's disease
34. Contralateral disappearance of parkinsonian signs after subthalamic hematoma
35. What happened to Vim thalamotomy for Parkinson's disease
36. Treatment of parkinsonism with levodopa