Enhanced reaction rate and enantioselectivity in lipase-catalyzed hydrolysis by addition of a crown ether

Tetrahedron Letters

Volumn 34, Issue 16, 1993, Pages 2617-2620

  Itoh, Toshiyuki ^a   Hiyama, Yuji ^a   Betchaku, Akio ^a   Tsukube, Hiroshi ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ACETOXYBUTYRONITRILE; CROWN ETHER DERIVATIVE; NITRILE; NITRITE; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

ARTICLE; ENANTIOMER; ENZYME ACTIVITY; HYDROLYSIS; PRIORITY JOURNAL; PSEUDOMONAS; REACTION ANALYSIS;

EID: 0027478958     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(00)77639-8     Document Type: Article

References (17)

1. Enzymes as Catalysts in Synthetic Organic Chemistry [New Synthetic Methods (53)]
2. Enhanced reactivity and enantioselectivity in lipase-catalysed hydrolysis of 12-crown-4 ester via crown ether?metal complexation
3. Enhanced enantioselectivity of the lipase-catalyzed hydrolysis by the addition of a catalytic amount of an amino alcohol.
4. Dissolution of proteins in organic solvents using macrocyclic polyethers: association constants of a cytochrome c?[1,2-14C2]-18-crown-6 complex in methanol
5. The effect of crown ethers on enzyme-catalysed reactions in organic solvents
6. Nuclear magnetic resonance enantiomer regents. Configurational correlations via nuclear magnetic resonance chemical shifts of diastereomeric mandelate, O-methylmandelate, and .alpha.-methoxy-.alpha.-trifluoromethylphenylacetate (MTPA) esters
7. Quantitative analyses of biochemical kinetic resolutions of enantiomers
8. Synthesis and alkali-cation complexing properties of 12-crown-4 derivatives.