Reactivity of orthoquinones involved in tyrosinase-dependent cytotoxicity: Differences between alkylthio-and alkoxy-substituents

Melanoma Research

Volumn 2, Issue 5, 1992, Pages 283-294

  Cooksey, C J ^a   Jimbow, K ^b   Land, E J ^c   Riley, P A ^d  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF ALBERTA   (Canada)

^c CHRISTIE HOSPITAL   (United Kingdom)

^d ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

Cytotoxicity; Orthoquinones; Quinone thiol adducts; Thiols; Tyrosinase

Indexed keywords

CATECHOL; CYSTEINE; GLUTATHIONE; MONOPHENOL MONOOXYGENASE; PHENOL DERIVATIVE; QUINONE DERIVATIVE;

ARTICLE; CHEMICAL REACTION KINETICS; CHEMICAL STRUCTURE; DRUG CYTOTOXICITY; ENZYME SUBSTRATE; MELANOGENESIS; MELANOMA; NUCLEAR MAGNETIC RESONANCE; OXIDATION; PULSE RADIOLYSIS; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION;

CELL SURVIVAL; COMPARATIVE STUDY; DRUG DESIGN; HUMAN; INDICATORS AND REAGENTS; MAGNETIC RESONANCE SPECTROSCOPY; MELANOMA; MONOPHENOL MONOOXYGENASE; QUINONES; SPECTROPHOTOMETRY; STRUCTURE-ACTIVITY RELATIONSHIP; SULFHYDRYL COMPOUNDS; SUPEROXIDES; SUPPORT, NON-U.S. GOV'T;

EID: 0027476649     PISSN: 09608931     EISSN: 14735636     Source Type: Journal    
DOI: 10.1097/00008390-199212000-00001     Document Type: Article

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