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Tetrahedron Letters
Volumn 34, Issue 16, 1993, Pages 2593-2596
Towards the synthesis of HIV-protease inhibitors. Synthesis optically pure 3-carboxyl-decahydroisoquinolines.
Author keywords

[No Author keywords available]
Indexed keywords

ANTIVIRUS AGENT; ISOQUINOLINE DERIVATIVE; PROTEINASE INHIBITOR;
EID: 0027474335     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(00)77633-7     Document Type: Article
Times cited : (36)
References (14)
  • 1
    • 84918743059 scopus 로고    scopus 로고
    • A C.A.S. on-line search produced 74 references on decahydroisoquinoline-3-carboxylate derivatives, the majority of which were patents.
  • 5
    • 84918762172 scopus 로고    scopus 로고
    • F. Hoffmann- LaRoche AG, European Patent Application 90123697.6, 1990.
  • 6
    • 0012980002 scopus 로고
    • Enzym-katalysierte asymmetrische Synthese, IV. Synthese homochiraler Bausteine für die enantioselektive Totalsynthese von Cyclopentanoiden mit Esterase-katalysierter asymmetrischer Schlüsselreaktion
    • 1H NMR analysis of the ephedrine salt and comparison to the literature data:
    • (1986) Liebigs Annalen der Chemie , pp. 687
    • Gais1    Lukas2    Bull3    Braun4    Lindner5
  • 11
    • 84918753231 scopus 로고    scopus 로고
    • spB-H = 90 Hz) as the only detectable borane species.
  • 14
    • 84918749919 scopus 로고    scopus 로고
    • 13C NMR and Mass spectra. The structure and absolute stereochemistry of the final product (1) was established by comparison with an authentic sample provided by Dr. Wayne Thompson whom we gratefully acknowledge.

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