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Volumn 34, Issue 10, 1993, Pages 1643-1646

Palladium-catalyzed coupling of organic halides and tertiary allylic amines

Author keywords

Heck reaction; palladium catalysis; perfluoroalkyl iodide; phenyl iodide; radical addition.

Indexed keywords

AMINE;

EID: 0027473993     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(93)85030-Z     Document Type: Article
Times cited : (15)

References (11)
  • 6
    • 84914361053 scopus 로고    scopus 로고
    • After the work up, only the aldehyde was recovered.
  • 8
    • 84914361042 scopus 로고    scopus 로고
    • To a smaller extent, solvents can also affect selectivity of the palladium-catalyzed arylation of allylic alcohols. When the coupling of phenyl iodide and 2-methylprop-2-enol was carried out in toluene, we obtained a mixture of aldehyde and isomeric allylic alcohols or bis-arylated compounds arising from further arylation of allylic alcohols.
  • 9
    • 84914361041 scopus 로고    scopus 로고
    • According to rif.9, the reaction was completely inhibited by nitrotoluene.
  • 11
    • 84914361040 scopus 로고    scopus 로고
    • We have never detected the 2-iodo-2-methyl-3-perfluoro-alkylpropyl tertiary amine, but, in our opinion, the 2-hydroxy-2-methyl-3-perfluoroalkylpropyl tertiary amine that we found when the reaction was performed in toluene provides circumstantial evidence that this easily-hydrolysable iododerivative is indeed formed.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.