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Volumn 53, Issue 1, 1993, Pages 89-95

Genetically determined drug-metabolizing activity and desipramine-associated cardiotoxicity: A case report

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; DAPSONE; DEBRISOQUINE; DESIPRAMINE; DRUG METABOLITE; MEPHENYTOIN;

EID: 0027471030     PISSN: 00099236     EISSN: None     Source Type: Journal    
DOI: 10.1038/clpt.1993.13     Document Type: Article
Times cited : (35)

References (11)
  • 1
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    • Role of P450IID6, the target of the sparteine-debrisoquin oxidation polymorphism, in the metabolism of imipramine
    • Brosen K, Zeugin T, Meyer UA. Role of P450IID6, the target of the sparteine-debrisoquin oxidation polymorphism, in the metabolism of imipramine. CLIN PHARMACOL THER 1991;49:609-17.
    • (1991) Clin Pharmacol Ther , vol.49 , pp. 609-617
    • Brosen, K.1    Zeugin, T.2    Meyer, U.A.3
  • 2
    • 0020662811 scopus 로고
    • The debrisoquine hydroxylation test predicts steady-state plasma levels of desipramine
    • Bertilsson L, Aberg-Wistedt A. The debrisoquine hydroxylation test predicts steady-state plasma levels of desipramine. Br J Clin Pharmacol 1983;15:388-90.
    • (1983) Br J Clin Pharmacol , vol.15 , pp. 388-390
    • Bertilsson, L.1    Aberg-Wistedt, A.2
  • 3
    • 0023937894 scopus 로고
    • Cardiovascular effects of the standard tricyclic antidepressants
    • Classman AH, Pardell R, Woodring S. Cardiovascular effects of the standard tricyclic antidepressants. Clin Chem 1988;34:856-8.
    • (1988) Clin Chem , vol.34 , pp. 856-858
    • Classman, A.H.1    Pardell, R.2    Woodring, S.3
  • 4
    • 84944658068 scopus 로고
    • Cardiovascular effects of tricyclic and tetracyclic antidepressants
    • Burckhardt D, Raeder E, Muller V, Imhof P, Neubauer H. Cardiovascular effects of tricyclic and tetracyclic antidepressants. JAMA 1978;239:213-6.
    • (1978) JAMA , vol.239 , pp. 213-216
    • Burckhardt, D.1    Raeder, E.2    Muller, V.3    Imhof, P.4    Neubauer, H.5
  • 5
    • 0026536551 scopus 로고
    • Characterization of human cytochrome P450 enzymes
    • Guengerich FP. Characterization of human cytochrome P450 enzymes. FASEB J 1992;6:745-748.
    • (1992) FASEB J , vol.6 , pp. 745-748
    • Guengerich, F.P.1
  • 6
    • 0027077439 scopus 로고
    • Human liver microsomal W-hydroxylation of dapsone by cytochrome P4503A4
    • Fleming C, Branch RA, Wilkinson GR, Guengenrich P. Human liver microsomal W-hydroxylation of dapsone by cytochrome P4503A4. Mol Pharmacol 1992;41: 975-80.
    • (1992) Mol Pharmacol , vol.41 , pp. 975-980
    • Fleming, C.1    Branch, R.A.2    Wilkinson, G.R.3    Guengenrich, P.4
  • 7
    • 0018086989 scopus 로고
    • Simultaneous analysis of dapsone and monoacetyldapsone employing high performance liquid chromatography: A rapid method for determination of acetylator phenotype
    • Can K, Oates JA, Nies AS, Woosley RL. Simultaneous analysis of dapsone and monoacetyldapsone employing high performance liquid chromatography: a rapid method for determination of acetylator phenotype. Br J Clin Pharmacol 1978;6:421-7.
    • (1978) Br J Clin Pharmacol , vol.6 , pp. 421-427
    • Can, K.1    Oates, J.A.2    Nies, A.S.3    Woosley, R.L.4
  • 8
    • 0021684926 scopus 로고
    • Deficiency of mephenytoin hydroxylation in a Caucasian population: Frequency of a new oxidative drug metabolism polymorphism
    • Wedlund PJ, Aslanian WS, McAllister CB, Wilkinson GR, Branch RA. Deficiency of mephenytoin hydroxylation in a Caucasian population: frequency of a new oxidative drug metabolism polymorphism. CLIN PHARMACOL THER 1984;36:773-80.
    • (1984) Clin Pharmacol Ther , vol.36 , pp. 773-780
    • Wedlund, P.J.1    Aslanian, W.S.2    McAllister, C.B.3    Wilkinson, G.R.4    Branch, R.A.5
  • 11
    • 0025608201 scopus 로고
    • The contribution of W-hydroxylation and acetylation to dapsone pharmacokinetics in normal subjects
    • May DO, Porter JA, Uetrecht JP, Wilkinson GR, Branch RA. The contribution of W-hydroxylation and acetylation to dapsone pharmacokinetics in normal subjects. CLIN PHARMACOL THER 1990;48:619-27.
    • (1990) Clin Pharmacol Ther , vol.48 , pp. 619-627
    • May, D.O.1    Porter, J.A.2    Uetrecht, J.P.3    Wilkinson, G.R.4    Branch, R.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.