Structure-function analysis of human IL-6 receptor: Dissociation of amino acid residues required for IL-6-binding and for IL-6 signal transduction through gp130

EMBO Journal

Volumn 12, Issue 4, 1993, Pages 1705-1712

  Yawata, H ^a   Yasukawa, K ^a   Natsuka, S ^a   Murakami, M ^a   Yamasaki, K ^a   Hibi, M ^a   Taga, T ^a   Kishimoto, T ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

Cytokine receptor family; IL 6 receptor; Ligand binding; Signal transduction; Structure function analysis

Indexed keywords

INTERLEUKIN 6; INTERLEUKIN RECEPTOR;

AMINO ACID SUBSTITUTION; ARTICLE; HUMAN; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

EID: 0027467218     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1993.tb05815.x     Document Type: Article

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