Potency mismatch for behavioral and biochemical effects by dopamine receptor antagonists: implications for the mechanism of action of clozapine

Psychopharmacology

Volumn 110, Issue 3, 1993, Pages 273-279

  Wadenberg, Marie Louise ^a   Ahlenius, Sven ^a,b   Svensson, Torgny H ^b  

^a Astra Arcus AB ^*  (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Behavior; Clozapine; Conditioned avoidance response; Dopamine receptor subtypes; Dopamine synthesis; Monoamines; Raclopride; SCH 23390

Indexed keywords

3 HYDROXYBENZYLHYDRAZINE; 5 HYDROXYTRYPTOPHAN; 8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; CLOZAPINE; DOPA; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; DOPAMINE RECEPTOR; DOPAMINE RECEPTOR BLOCKING AGENT; RACLOPRIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AVOIDANCE BEHAVIOR; BEHAVIOR; BIOSYNTHESIS; BRAIN REGION; CATALEPSY; CONTROLLED STUDY; DOPAMINE METABOLISM; DRUG MECHANISM; MALE; NEOSTRIATUM; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; RAT; SUBCUTANEOUS DRUG ADMINISTRATION;

ANIMAL; AVOIDANCE LEARNING; BEHAVIOR, ANIMAL; BIOGENIC MONOAMINES; BRAIN CHEMISTRY; CATALEPSY; CLOZAPINE; DOPAMINE ANTAGONISTS; MALE; RACLOPRIDE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D2; SALICYLAMIDES; SCH-23390; SUPPORT, NON-U.S. GOV'T;

EID: 0027466856     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/BF02251281     Document Type: Article

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