Maturation‐dependent regulation of protein kinase C activity by vitamin D3 metabolites in chondrocyte cultures

Journal of Cellular Physiology

Volumn 157, Issue 2, 1993, Pages 271-278

  Sylvia, V L ^a   Schwartz, Z ^a,b   Schuman, L ^a   Morgan, R T ^a   Mackey, S ^a,c   Gomez, R ^a   Boyan, B D ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^c WILFORD HALL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

24,25 DIHYDROXYCOLECALCIFEROL; CALCITRIOL; COLECALCIFEROL; CYCLOHEXIMIDE; DACTINOMYCIN; ENZYME INHIBITOR; GENISTEIN; PROTEIN KINASE C; PROTEIN TYROSINE KINASE;

ANIMAL CELL; ARTICLE; CARTILAGE CELL; CELL DIFFERENTIATION; CHONDROGENESIS; CONTROLLED STUDY; ENZYME REGULATION; MATURATION; NONHUMAN; PRIORITY JOURNAL; RAT;

24,25-DIHYDROXYVITAMIN D 3; ANIMAL; BLOTTING, WESTERN; CALCITRIOL; CELL DIFFERENTIATION; CELLS, CULTURED; CHOLECALCIFEROL; CYCLOHEXIMIDE; DACTINOMYCIN; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTRENES; GENISTEIN; GROWTH PLATE; ISOFLAVONES; PHOSPHOLIPASE C; PROTEIN KINASE C; PROTEIN-TYROSINE KINASE; PYRROLIDINONES; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; TIME FACTORS;

ANIMALIA;

EID: 0027452531     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.1041570209     Document Type: Article

References (35)

1. Parathyroid hormone causes translocation of protein kinase C from cytosol to membranes in rat osteosarcoma cells
2. Genistein, a specific inhibitor of tyrosine‐specific protein kinases
3. Vesicles associated with calcification in the matrix of epiphyseal cartilage
4. Mixed micelle assay of protein kinase C
5. 3 and human bone‐derived cells in vitro and effects on alkaline phosphatase, type I collagen and proliferation
6. Inositol lipids and cell proliferation
7. Inhibition of phospholipase C—depndent processes by U‐73,122
8. Current concepts of the physiology and biochemistry of calcification
9. −2 on phospholipid metabolism in dispersed porcine parathyroid cells
10. Differential expression of phenotype by resting zone and growth region costochondral chondrocytes in vitro
11. In vitro studies on the regulation of endochondral ossification by vitamin D
12. 3 effects on collagen and DNA synthesis in periosteum and periosteum‐free calvaria
13. Nongenomic activation of the calcium message system by vitamin D metabolites in osteoblast‐like cells
14. Rapid actions of vitamin D compounds
15. 3‐mediated rapid stimulation of intestinal calcium transport, (transcaltachia)
16. Hormoneinduced redistribution of calcium‐activated phospholipid‐dependent protein kinase in pituitary gonadotrophs
17. Studies on a cyclic nucleotide‐independent protein kinase and its proenzymes in mammalian tissues
18. 3 on calcium ion fluxes in costochondral chondrocyte cultures
19. 3 on the phosphoinositide metabolism in rat enterocytes
20. 3 on alkaline phosphatase in osteoblastic osteosarcoma cells
21. 3 increases intracellular calcium in human keratinocytes by stimulating phosphatidylinositol turnover
22. Structural and functional diversities of a family of signal transducing protein kinases, protein kinase C family; two distinct classes of PKC, conventional cPKC and Novel nPKC
23. +2 concentration of osteoblastic cells, clone MC3T3‐E1
24. 2 activity on growth zone and resting zone cartilage cells in vitro
25. 2 specific activities
26. Effects of vitamin D metabolites on collagen production and cell proliferation of growth zone and resting zone cartilage cells in vitro
27. 3 in growth zone and resting zone chondrocytes
28. 3 by growth zone and resting zone chondrocytes is dependent on cell maturation and is regulated by hormones and growth factors
29. 2 synthesis by vitamin D metabolites in growth zone and resting zone chondrocyte cultures is dependent on cell maturation
30. Measurement of protein using bicinchoninic acid
31. 2
32. 3 is dependent on cell maturation
33. 3 on the metabolism of polyphosphoinositides in murine epidermal keratinocytes
34. 3 in bone
35. 3 stimulates membrane phosphoinositide turnover, activates protein kinase C, and increases cytosolic calcium in rat colonic epithelium