A review of oxycodone's clinical pharmacokinetics and pharmacodynamics

Journal of Pain and Symptom Management

Volumn 8, Issue 2, 1993, Pages 63-67

  Pöyhiä, Reino ^a,b   Vainio, Anneli ^a,b   Kalso, Eija ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b Department of Anesthesia Terhokoti Hospice ^*  (Finland)

Author keywords

acute postoperative pain; cancer pain; morphine; Oxycodone; pharmacology; posttraumatic pain

Indexed keywords

MORPHINE; OXYCODONE;

ANALGESIC ACTIVITY; ANTINOCICEPTION; CANCER PAIN; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG EFFICACY; DRUG ELIMINATION; DRUG HALF LIFE; DRUG INDICATION; DRUG POTENCY; DRUG STRUCTURE; DRUG USE; GASTROINTESTINAL SYMPTOM; HALLUCINATION; HUMAN; INTRAMUSCULAR DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; ORAL DRUG ADMINISTRATION; POSTOPERATIVE PAIN; RECEPTOR AFFINITY; RECTAL DRUG ADMINISTRATION; REVIEW; SUBCUTANEOUS DRUG ADMINISTRATION;

BIOLOGICAL AVAILABILITY; HUMAN; OXYCODONE; THERAPEUTIC EQUIVALENCY;

EID: 0027450550     PISSN: 08853924     EISSN: None     Source Type: Journal    
DOI: 10.1016/0885-3924(93)90101-Z     Document Type: Review

References (31)

1. Problems with the use of oxycodone compound in patients with chronic pain
2. Transdermal-controlled administration of oxycodone
3. Pharmacologic approaches to cancer pain
4. Opioid therapy in malignant disease
5. Analgesic drugs
6. Opioid analgesics in cancer pain: current practice and controversies
7. Analgesic studies of codeine and oxycodone in patients with cancer. I. Comparisons of oral with intramuscular codeine and of oral with intramuscular oxycodone
8. Analgesic studies of codeine and oxycodone in patients with cancer II. Comparisons of intramuscular oxycodone with intramuscular morphine and codeine
9. Morphine and oxycodone hydrochloride in the management of cancer pain
10. Intravenous morphine and oxycodone for pain after abdominal surgery
11. Synthetic substances with morphine-like effect relationship between analgesic action and addiction liability with a discussion of the chemical structure of addictionproducing substances
12. Influence of polarity on dose-response relationships of intrathecal opioids in rats
13. The pharmacokinetics of oxycodone after intravenous injection in adults
14. The pharmacokinetics and metabolism of oxycodone after intramuscular and oral administration to healthy subjects
15. Effects of other drugs and pathologic states on opioid disposition and response
16. Morphine and oxycodone in the management of cancer pain plasma levels determined by chemical and radioreceptor assays
17. Determination of oxycodone and a major metabolite
18. Mu receptor binding of some commonly used opioids and their metabolites
19. Psychomotor, respiratory and neuroendocrinological effects of a μ-opioid receptor agonist (oxycodone) in healthy volunteers
20. Pharmacodynamic interactions of oxycodone and amitriptyline in healthy volunteers
21. Antinociceptive effects and central nervous system depression caused by oxycodone and morphine in rats
22. Comparison of IM lysine acetylsalicylate and oxycodone in the treatment of pain after operation
23. Diclofenac and oxycodone in treatment of postoperative pain: a double-blind trial
24. A comparison of pethidine, pritiramide and oxycodone in patients with pain following cholecystectomy
25. Pharmacological management of cancer pain
26. Dose-ranging study of oxycodone for advanced cancer pain [abst]
27. Opioid analgesics in the management of pain in patients with cancer a review
28. Continuous subcutaneous infusion of opioids in terminal cancer pain [abst]
29. Sublingual absorption of selected opioid analgesics